Harleen Saini
@sainiharleenPostdoctoral fellow in the Moazed lab studying how RNA controls transcription.
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UMass Chan Medical School researcher Victor R. Ambros, PhD, arrives on the @UMassChan campus with his wife, Rosalind "Candy" Lee, after learning he is sharing the 2024 @NobelPrize in Physiology or Medicine. WATCH news conference at 10 a.m. EST: direc.to/mmGC #NobelPrize
Excited that CREME (Cis-Regulatory Element Model Explanations) is published in @NatureGenet! Work led by @ToneyanSh! tl;dr CREME interprets rules of gene regulation learned by genomic deep learning models using carefully designed in silico perturbations. rdcu.be/dT3kq
Check out my piece on the recent papers describing an H3-H4 chaperone role for the Fork Protection Complex component Mrc1. Congrats to @Moazed_Lab, @GrothLab, Thon, and Jia labs! The awesome power of yeast coupled with AlphaFold2-multimer! cell.com/cell/abstract/…
Do you love RNA? Are you interested in learning how to use high-throughput sequencing methods to investigate RNA biology? The Niederer lab is hiring! Please contact me if you have any questions about our work or the position 😃 #TeamTranslation careers.umich.edu/job_detail/231…
Requirements for establishment and epigenetic stability of mammalian heterochromatin biorxiv.org/content/10.110… H3K9me-dependent heterochromatin can be inherited for a limited number of divisions in mESCs but becomes stable upon differentiation @antatarakis @sainiharleen @Moazed_Lab
Excited to share our recent work on the establishment and epigenetic inheritance of mammalian heterochromatin and the role of DHX9 R-loop resolvase in safeguarding heterochromatin stability. #EpigeneticInheritance, #Heterochromatin, #Rloops #GeneSilencing. biorxiv.org/content/10.110…
Excited to see colabfold published! nature.com/articles/s4159… Special thanks to @thesteinegger and @milot_mirdita (for MMseqs2) without whom I would have never considered to preprint let alone attempt to publish our notebook! (1/3)
Our group is looking for a research assistant who seeks to indulge in an independent project of their own. We ask how vision arises from the function of molecules, cells, and circuits--in ways that support distinct needs within and across species. brain.harvard.edu/?people=michae…
Protocol question! For years, we've linked to the Miller Lab Protocol in our Plasmids 101 resources. But the link is now dead 😰Does anyone know of a live link to the Miller Lab Protocol or have suggestions for a replacement?
If you are interested in studying the mechanism of epigenetics and heterochromatin, take a look at our opening positions below and apply! More descriptions of our lab's research can be found here: moazed.hms.harvard.edu/research
Opening for a new lab manager and senior scientist in the Moazed lab! Great opportunity to join our heterochromatin/epigenetics group. Apply here for lab manager: bit.ly/3qnG5OM Apply here for senior scientist: bit.ly/31UNv2S
🧑🔬The @Moazed_Lab is hiring! Join us in studying the molecular/biochemical mechanisms of silencing DNA and keeping it🔇 Learn more about us here: moazed.hms.harvard.edu Please spread the word and apply below👇
Opening for a new lab manager and senior scientist in the Moazed lab! Great opportunity to join our heterochromatin/epigenetics group. Apply here for lab manager: bit.ly/3qnG5OM Apply here for senior scientist: bit.ly/31UNv2S
The great Harvard biologist E.O. Wilson died. My never-before-seen video obituary of him for @nytimes ran today along with an excellent written obit by @carlzimmer Wilson was brilliant, prolific, generous, and kind. Our greatest advocate for biodiversity. nytimes.com/video/obituari…
The Koo lab and the Kinney lab at Cold Spring Harbor Laboratory have an exciting joint postdoc opportunity to research at the intersection of machine learning, biophysics, and genomics. For more info, check out: nature.com/naturecareers/… DM if you have any questions. Please RT!
HHMI News: @shulgina_kate and HHMI Investigator @ribosaur have developed Codetta, a new computational method for predicting genetic codes. In scanning over 250,000 genome sequences, they found five never-before-seen codes. bit.ly/3F2mND5
❗We found FIVE new genetic codes in a screen of >250,000 bacterial and archaeal genomes. All of the reassignments affect arginine codons—the first known sense codon changes in bacteria! (4/6)
Today my paper with @ribosaur on new genetic codes comes out in @eLife! It's been a labor of love over the past five years. Highlights in thread 🧵 (1/6) elifesciences.org/articles/71402
Now that I have 100K followers, I want to talk about #OvarianCancer. Specifically my gritty story. The goal is awareness. I hope you find this narrative informative.
Thanks, @ribosaur for highlighting this blog post. And thank you, @c_outeiral, for an excellent summary of AlphaFold2. Transformers don't scare me no more! 🤠
Opening for a new lab manager and senior scientist in the Moazed lab! Great opportunity to join our heterochromatin/epigenetics group. Apply here for lab manager: bit.ly/3qnG5OM Apply here for senior scientist: bit.ly/31UNv2S
Want to know more about AlphaFold 2? I wrote a commentary explaining how it works, why it performs so well, and what it might do for biology now that it is freely available. blopig.com/blog/2021/07/a…
Our paper for tRNAscan-SE 2.0 is finally out! It covers features and comparison of #tRNA predictions with examples in all domains of life. Thanks everyone for all the feedbacks on this multi-year project! academic.oup.com/nar/advance-ar…
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