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Moazed Lab

@Moazed_Lab

We're the Moazed lab @ HMS/HHMI. Posts managed by current lab members and Dr. Danesh Moazed.

Joined June 2021
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Moazed Lab Reposted

All 268 AlphaFold predictions associated with our study are publicly available on #ModelArchive: modelarchive.org/doi/10.5452/ma…. These predictions range from unbiased screening (histones or FACT subunits against core replisome subunits) to hypothesis-driven subcomplex predictions.


Moazed Lab Reposted

Check out my piece on the recent papers describing an H3-H4 chaperone role for the Fork Protection Complex component Mrc1. Congrats to @Moazed_Lab, @GrothLab, Thon, and Jia labs! The awesome power of yeast coupled with AlphaFold2-multimer! cell.com/cell/abstract/…


Moazed Lab Reposted

Happy to share with the world that the main body of my PhD thesis (and my rotation project) on the mechanism for replisome-mediated parental histone inheritance is published in @CellCellPress today🥰! cell.com/cell/fulltext/…


Moazed Lab Reposted

TASOR loss not only disrupts H3K9me3 at L1s but increases the half-life of L1 RNA, indicating that increased L1 RNA upon TASOR loss may be partially attributed to decreased degradation, akin to the RITS complex @Moazed_Lab . Complementing findings by @Margottin11 @torbenheick

carlosapinzona's tweet image. TASOR loss not only disrupts H3K9me3 at L1s but increases the half-life of L1 RNA, indicating that increased L1 RNA upon TASOR loss may be partially attributed to decreased degradation, akin to the RITS complex @Moazed_Lab . Complementing findings by @Margottin11 @torbenheick

Congratulations and farewell to @dadmehr_y as he embarks on an exciting journey towards an M.D. at UCLA! We wish you all the success and fulfillment as you pursue your dreams in medicine.

Moazed_Lab's tweet image. Congratulations and farewell to @dadmehr_y as he embarks on an exciting journey towards an M.D. at UCLA! We wish you all the success and fulfillment as you pursue your dreams in medicine.

Congratulations to Dr. Wade Harper, Dr. Spyros Artavanis-Tsakonas and Dr. Danesh Moazed for their election to the National Academy of Sciences. This is a well deserved recognition for their research excellence and contributions to science. @HarvardCellBio


Moazed Lab Reposted

Excited to share our recent work on the establishment and epigenetic inheritance of mammalian heterochromatin and the role of DHX9 R-loop resolvase in safeguarding heterochromatin stability. #EpigeneticInheritance, #Heterochromatin, #Rloops #GeneSilencing. biorxiv.org/content/10.110…


We are very happy to share our recent work on the requirements for establishment and epigenetic stability of mammalian heterochromatin. biorxiv.org/content/10.110… @antatarakis @sainiharleen @DaneshMoazed #epigenetics #H3K9me #heterochromatin


We are very happy to share our pre-print on the Three Rules for Epigenetic Inheritance of Human Polycomb Silencing! What are these three rules? Read more to find out…. biorxiv.org/content/10.110… #epigenetics #polycomb #heterochromatin


Opening for a new lab manager and senior scientist in the Moazed lab! Great opportunity to join our heterochromatin/epigenetics group. Apply here for lab manager: bit.ly/3qnG5OM Apply here for senior scientist: bit.ly/31UNv2S


We are thrilled to see the very talented @dorkarole as one of the @DamonRunyon fellows this year! Congratulations, Karole!! From all of us in the Moazed lab!

Delighted to announce our newest class of Damon Runyon Fellows! We're honored to award seventeen remarkable postdoctoral scientists with independent funding to kickstart their research careers: bit.ly/3yBfHmr



Would you like to maintain your knowledge of what's new in epigenetics? Then check out our most recent paper on 'A Composite DNA Element that Functions as a Maintainer Required for Epigenetic Inheritance of Heterochromatin' cell.com/molecular-cell…


Welcome to the lab @R_SotomayorMena ! We are all super excited to have you on board


Moazed Lab Reposted

Welcome, neighbors! Great to have you on Twitter #HMS


Hey #sciencetwitter ... the Moazed lab is here! Follow us for all things chromatin #AcademicTwitter


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