Rikki Garner
@rikkigarnerHelen Hay Whitney Fellow with @SeanMegason @HMS_SysBio (PhD w/ Julie Theriot). Biophysicist and quantitative cell biologist, integrating theory and experiment.
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Excited to announce our work on cytoplasm heterogeneity with @MolinesArthur @fredchanglab is published @BiophysJ! Check out the brand new analysis on ergodicity, where we estimate that spatial variation in cytoplasm viscosity has a domain size of ~200 nm. rb.gy/f76giz
Think the cytoplasm is well-mixed? Think again. In my latest work with @MolinesArthur and @fredchanglab we found the apparent viscosity of the cytoplasm may vary up to 100-fold (!) within individual cells, and 10-fold (!) between cells. A thread: (1/8) biorxiv.org/cgi/content/sh…
Turns out condensates grow faster when they are on both sides of a membrane! @YohanLee325 shows it beautifully in our new preprint. Transmembrane coupling accelerates the growth of liquid-like protein condensates biorxiv.org/content/10.110…
Thrilled to share our latest work from my postdoc with @MartinLabMIT in @Dev_Cell ! We uncovered a mechanism linking DV axial patterning with AP axis extension through patterned cell-cell adhesion. Intrigued? Dive into the details here!
Online now: Postdoc Nat Clarke's @natclarke8 excellent work on a mechanism that coordinates tissue folding and axis extension. Great job and congratulations Nat!
We're finally out at @NatureComms Congrats to @jzhao111, Nick Lammers, @yangjoonkim, Simon Alamos and @gabrimartini_ny ! nature.com/articles/s4146…
New preprint by @jzhao111, Nick Lammers, @yangjoonkim and Simon Alamos! Combining optogenetics, live imaging and theoretical modeling to biochemically dissect repressor action in living animals. biorxiv.org/content/10.110…
Thrilled to share my postdoctoral work exploring how brain mechanics influences metastasis, now out in @NatureCellBio Check it out! #ChenLab @BUmechanobio @BioDesignCenter @wyssinstitute nature.com/articles/s4155…
APS March meeting abstract deadline is coming up - October 25! Submit to the Morphogenesis category 04.01.11 - Invited talks will be by Emily Gehrels @EmilyGehrels and Anna Erzberger @ErzbergerGroup
Please submit your abstract for “Physics of the Cytoskeleton” at the 2025 APS Global Physics Summit in Anaheim CA by October 25. This is @ApsDbio Focus Session 04.01.03, co-organized with @DrSteffi Join us and invited speakers @SFuerthauer, @makitomiyazaki !
This story started 5y ago with my lab. Spearheaded by fearless 1st authors @theopi and Olivia Leland. Theopi is now a PhD student at @BrownUniversity Olivia is a physics PhD student at @BrandeisU, a self-taught biologist, and made us love soft matter. A (very long) thread (1/24)
Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea biorxiv.org/cgi/content/sh… #biorxiv_cellbio
APS March Meeting abstracts due Oct 25th! @LilianHsiao and I are organizing focus session 02.01.13 hosted by @ApsDsoft "Brittle-to-ductile transitions in soft amorphous networks." We aim to bring together folks from soft matter to polymers to biological systems. RTs appreciated.
So excited to announce that the Kappel Lab will open at @UCLA @uclachem in July 2025! We’ll combine high-throughput experiments and computation to build predictive sequence-structure-function models of RNA, proteins, and their interactions. More here: sites.google.com/view/kappellab/
We’re excited to announce that five talented researchers and educators will be joining our department in the coming months! Learn more: bit.ly/welcomenewfacu… @TomPFay @KalliKappel @LindertLab @petroviclab @uclaphyssci
Excited to share our updated manuscript on FragFold, the massively parallel AlphaFold-based approach we’ve developed to discover protein fragment inhibitors at scale -- w/ @SassSeabass, @keating_lab, and @GeneWeiLiLab biorxiv.org/content/10.110… (1/n)
Want to design genetically encoded inhibitors of your favorite protein? Thrilled to announce our latest work w/ @SassSeabass, @keating_lab, & @GeneWeiLiLab, where we leverage massively parallel AlphaFold predictions to discover peptide inhibitors. biorxiv.org/content/10.110… (1/n)
Really excited to share our preprint on #Galvanotaxis! We identify Galvanin, a membrane protein acting as an electric field sensor that guides cell migration. Check it out: biorxiv.org/content/10.110… #CellBiology #CRISPRi #Migration (Thanks for the support @JCChildsFund and @NIGMS)
We & @PoLDresden are happy to host the "Physical Biology of the Cell" course by Rob Philipps @Caltech once again! This multidisciplinary, 5-day event leverages a use of quantitative thinking to query the nature of the living. Instructors: @AIDuarte10 @jkondev & @kianfaizi
We are excited to have Dr. Fred Chang present in the Physical Properties of the Cytoplasm online seminar series next week. For details see flyer. For more, visit cytophys.org
interesting finding! Galvanin is an electric-field sensor for directed cell migration biorxiv.org/content/10.110…
CTB is opening a faculty search for an Assistant Professor in Cell Biology! Check it out and apply here! aprecruit.ucsf.edu/JPF05256
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