Dylan Rausch
@dylanrauschCPH Bioscience PhD student with @tunepers. Studying CNS regulation of metabolism with single-cell 🧠 Crossfit 🏋️♀️ fantasy nerd 📚 Red Sox ⚾️
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I'm very excited to share my first postdoc preprint with @BoyiGuo and @stephaniehicks! Here we preset SpotSweeper - the first spatially-aware quality control methods developed for spatial transcriptomics. 🧵 biorxiv.org/content/10.110…
Fantastic new article from the @ClemmensenC lab! Here, the authors show that the compensatory response that counteracts weight gain and overfeeding is preserved in #obesity. @Metabolcenter nature.com/articles/s4146…
The time of day that we eat has significant impact on body weight and metabolic health but what determines those mealtimes? In a new study @NatureNeuro, we monitored daily oscillations in the activity of key hypothalamic hunger neurons expressing AgRP. ++ nature.com/articles/s4159…
Conserved GABAergic LepRbGlp1r neuron population plays crucial roles in the suppression of food intake by leptin and GLP1R agonists @UMich #weightloss @seeleyrj @lotte_bjerre #obesity jci.org/articles/view/…
We’re thrilled to share our preprint (collab with @marionilab) in which we use human POMC neurons to identify potential anti-obesity drugs, one of which seems to increase the efficacy of Semaglutide (Ozempic). Details on BioRxiv: bit.ly/3q44rjn. Thread below 🧵(1/16)
Great to have you in Copenhagen @Metabolcenter @SethBlackshaw and @ThomasDWKim 🙌 Inspiring talks from you and @Kirkeby_Lab on constructing and deconstructing the hypothalamus👌
Super excited to finally share this preprint from a collaboration with Marta Soden here at UW! We combined optogenetics with snRNAseq to reveal input- and cell-type-specific activation patterns in the VTA 👇 biorxiv.org/cgi/content/sh…
A Secret Sibling of Fat Cells Revealed! It's a great pleasure to finally be able to reveal the results of our single-cell transcriptomics study of adipogenesis: nature.com/articles/s4225… @NatMetabolism This work took 6+ years. Here's a 6 tweet summary 🧵 (1/6)
Mission-driven research generously funded by wealthy foundations is en vogue and offers many opportunities, but also challenges and risks: doi.org/10.15252/embr.… A critique by its former SAB of the surprise decision to close the Center for Protein Research in Denmark by NNF.
Finally its out!! Our little story about how the epigenome exerts transgenerational control over nervous system development. life-science-alliance.org/content/6/8/e2…
Super fun experience getting to share a bit on leptin and the neurobiology of obesity!
We kick off the first #pint23 in Copenhagen 🇩🇰 at Dispensary! First up, @dylanrausch is enlightening us on the #HungerNeurons and how we interact with food 🍪 @pintofscienceDK
We kick off the first #pint23 in Copenhagen 🇩🇰 at Dispensary! First up, @dylanrausch is enlightening us on the #HungerNeurons and how we interact with food 🍪 @pintofscienceDK
What triggers anorexia nervosa? We find that chronic stress can trigger willful seeking of a starvation-like state in mice. As in humans, this was enriched in female mice, particularly those predisposed to stress. biorxiv.org/content/10.110… 1/7
We are currently seeking a postdoctoral researcher to join our team. The position is fully funded, providing an excellent opportunity for individuals interested in the fields of neurodegeneration or neurodevelopment. If you have any questions, please contact tkim@dandrite.au.dk
JOIN OUR NEW GL @ThomasDWKim as #postdoc! You will work with molecular mechanisms and functions of diverse cell states and generate hypotheses utilizing data science Start October, DL 15 August, 3-Year pos. #postdocjobs au.dk/om/stillinger/… @NordicEMBL @AarhusUni_int @embl
Perfect place for a beer, maybe a snack 🍟and some science
📣 #pint23 in #Copenhagen #beautifulmind 🧠 Come to a great #science evening with @dylanrausch from @Metabolcenter and learn all about "hunger neurons" and what they are good for 🍽😋 🗓Monday, May 22th, 19.30 📍Dispensary (Nørrebrogade 184) ➡️More info bit.ly/3MwKEle
We talk about “good/bad quality” of single cell data, but people *define* quality much less often. Small 🧵 of thoughts on QC in single cell...
Working with scverse files natively in R @_lazappi_, @rcannood, @LouiseDck, and Martin Morgan prototyped an intermediate representation — an R object to interface between .h5ad files and R objects like SingleCellExperiment. github.com/scverse/anndat…
The end! As you may have already heard, @UCPH_CPR (where I work) will be shutting down over the coming years. This video covers what I know and think about this decision by the @novonordiskfond youtube.com/shorts/su-mgQM…
Looking much forward to the Danish Single-cell Symposium next week 🌿 So many great speakers from the US, Europe and Denmark 👇🙌 Focusing on spatial transcriptomics, cell-cell interactions, neuroscience applications and much more! @KhodosevichLab @Metabolcenter @UCPH_BRIC
Very excited to share our new paper in Cell metabolism on plasticity of a hunger synapse. Congrats to Kasia, Hannah, Stephan, and Marie-Luise! And, thanks to our collaborators at BIDMC: The Lowell lab
New! Online now: A synaptic amplifier of hunger for regaining body weight in the hypothalamus dlvr.it/SlQZlm
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Who to follow
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Tune H. Pers
@tunepers -
NNF Center for Basic Metabolic Research (CBMR)
@Metabolcenter -
Thue W Schwartz
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Jens Lund
@jens_lund -
Petar (he/him)
@pvtodorov -
Zach Gerhart-Hines
@Z_GerhartHines -
Sara Stinson
@stinson_SE -
Camilla Lund
@CamillaLund92 -
Fabian Finger
@FFinger_ -
Frederike Sass
@SassFrederike -
Matthew Gillum
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Elahu Sustarsic
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Ali Altıntaş
@_AliAltintas_
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