Alina Vaitsiankova
@vaitsiankovaPostdoc @CicciaAlberto lab @Columbia, PhD @keith_caldecott lab @GDSC_Sussex, @DarwinTrustofEd alumina.
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Very excited to share the results of my PhD at @keith_caldecott lab @GDSC_Sussex published today in @NatureSMB showing that unligated intermediates of Okazaki fragment processing are potent lesions for PARP trapping! 1/2 nature.com/articles/s4159…
Excited to share our recent study in @CellCellPress led by @GiuseppeLeuzzi_ on the dual role of the DNA translocase SMARCAL1 in regulating innate immune signaling and the expression of the PD-L1 immune checkpoint factor! authors.elsevier.com/a/1iWe5L7PXqPXc
Our @CellRepMethods Spotlight written by @vaitsiankova and @TanayThakar on the beautiful work of @bloodgenes, @jmartinrufino and colleagues using base editing screens to map variant effects in human hematopoiesis cell.com/cell-reports-m…
A PhD position is available in our lab img.cas.cz/skupina/hana-h…. I look forward to your applications.
Institute of Molecular Genetics is happy to announce that it has opened new PhD positions! 🎉👩🏼🔬🧑🔬 Are you looking for a place to boost your scientific career?🧬 Then visit our website and find a research group that suits you the most. ▶️ img.cas.cz/career/phd-pro…
Check our latest work on PARP2 and PARP inhibitors. Great collaboration with @zha_lab! Clinical PARP inhibitors allosterically induce PARP2 retention on DNA biorxiv.org/content/10.110…
Successfully passed my viva this Friday! I am Dr Alina now 🥳. Great thanks to my supervisor @keith_caldecott for all his support @GDSC_Sussex, to my examiners @EviSoutoglou and Jo Morris @Morris_Lab_DSBs for a great discussion, and finally to @DarwinTrustOfEd for funding my PhD!
Excited to share our work on global usage of replicative DNA polymerase in human cells out now in @NatureComms! Using profiles of leading & lagging strands, we also performed in-depth analysis on replication fork dynamics (initiation, termination, etc). rdcu.be/c0qc0
POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps dlvr.it/Sd2zhx
POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells dlvr.it/Sd2zlt
Our paper, led by @muratpier1, linking initiation of DNA replication and mutagenesis is out. Congrats to Pierre, @perezconsuelo_, @GuilbaudG & Alastair. Thanks to @MRC_LMB and to Simon Reed & Pat van Eijk at @cardiffuni & @BrokenStringBio! science.org/doi/10.1126/sc…
Never made a tweet about #cshlsymp22 since it was very intense 😂! However, was reminded about it today. Received these amazing DNA gloves 😍 from Lizzy, who I met at the conference. Great science and wonderful new friends @cshlmeetings
The amazing @CarolynBertozzi @NobelPrize @Stanford_ChEMH @Stanford !!!!!!
Happy to share the latest from our lab out today: Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2 cell.com/cell-reports/f…
The Ahel lab is excited to share our latest paper in @ScienceAdvances! We report a surprising new post-translational modification: ubiquitin linked to proteins via ADP-ribose. Congratulations to lead author Kang @Zhu1020277477 and all co-authors 🥳 science.org/doi/10.1126/sc…
Our story on how XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair is now online in @NatureComms Close collaboration with the labs of @LadurnerAndreas, @haicovanattikum, @hanneslans, @sheeradar nature.com/articles/s4146…
Our paper 'Molecular basis for the initiation of DNA primer synthesis’ has been published. Congratulations and big thanks for all the hard work to all colleagues form Aidan Doherty's lab and our great collaborators from Texas @CisnerosRes nature.com/articles/s4158…
Flap endonuclease 1 and DNA-PKcs synergistically participate in stabilizing replication fork to encounter replication stress in glioma cells dlvr.it/SNVT2L
To join the seminar of Petr Cejka, please register at: us06web.zoom.us/webinar/regist…
Come and join us in Birmingham for DNA replication and replication stress meeting!!
We are excited to announce that registration is now open for UK DNA Replication meeting 2022! Register now to join us on 6-8 September at the University of Birmingham. Find out more and register online: ow.ly/J1nC50IjBej
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