Similar User
@Schmidt_Lab_USF
@FGH_Lab
@AngeloTagl
@MargaritaSobo20
@antonywoliver
@RosadoLab
@MarekAdamow
@ayoubnlab
@KotaroTsukada
@IKalasova
Our paper 'Molecular basis for the initiation of DNA primer synthesis’ has been published. Congratulations and big thanks for all the hard work to all colleagues form Aidan Doherty's lab and our great collaborators from Texas @CisnerosRes nature.com/articles/s4158…
Two complementary reviews by the Doherty group discuss our current understanding of the structural and mechanistic basis of primer synthesis by Prim-Pols. doi.org/10.1042/BSR202… authors.elsevier.com/sd/article/S09…
Did you know that reverse transcriptases are capable of de novo DNA primer synthesis? It has been an surprising and incredibly exciting journey. Many thanks to all members of the Doherty lab for their fantastic work. academic.oup.com/nar/advance-ar…
Latest publication from the Doherty Lab — showing that Reverse Transcriptases can prime DNA synthesis. doi.org/10.1093/nar/gk…
New DNA replication research from @GDSC_Sussex @KZabrady et al!: Reverse transcriptases prime DNA synthesis academic.oup.com/nar/article/do…
Super collaborative effort involving many labs + teams. Huge thanks to Matt Day and Dominik Boos for leading the way, and to everyone else for having faith and holding on! doi.org/10.1101/2023.0…
Extremely pleased to see that this is now online. Perhaps my most “difficult” child, but absolutely worth the labour pains. Of course, huge kudos must go to everyone involved, as it would not have happened without you! doi.org/10.1093/nar/gk…
Today in partnership with @emblebi, we’re releasing predicted structures for nearly all catalogued proteins known to science, which will expand the #AlphaFold database by over 200x - from nearly 1 million to 200+ million structures: dpmd.ai/AF-22-TW 1/
First C.elegans paper from the lab! Find out why C.elegans needs two proteins to bind the telomeric G-overhang. @SchoolofBiology @StAndrewsBSRC biorxiv.org/content/10.110…
Smc5/6 aids chromosome replication & repair while restraining viral DNA species. Our new work reports the first DNA-bound structure of Smc5/6. Congrats to all authors, particularly @Shibai6 from @ZhaoLab_SKI & You Yu from Patel Lab at @MSKCANCERCENTER 1/5 pnas.org/doi/10.1073/pn…
Happy to report that this study is now published #openaccess nature.com/articles/s4159…
#cryoEM #MicroED with electron counting. Protein structure at 0.8A resolution. Ab initio phasing for two proteins facilitated by electron counting on a falcon 4 direct electron detector. A section of the map is shown below biorxiv.org/content/10.110…
ColabFold makes folding with #AlphaFold & #RoseTTAfold accessible to everyone. Our MSA server processed >1.6 million requests to date. We thank the community for all the help to improve Colabfold. Now published @naturemethods 📄 nature.com/articles/s4159…
Distinct loaders for viral restriction and chromosome maintenance by Smc5/6!? 🤓 Exciting work identifying a paralogue of Nse5 (and SLF1) (Smc5/6 loader) with roles in viral restriction: biorxiv.org/content/10.110…
Happy to share our work reconstituting DNA replication with purified human proteins in @Nature I worked on this in the last year of my postdoc @MRC_LMB - fantastic to see the great work the team has done since then and the finished product! Congrats all! nature.com/articles/s4158…
Postdoc opportunity (closes 24 May): Interested in mechanisms of cyclic nucleotide-based antiviral defence? Come and join us at St Andrews (view from the lab below) tinyurl.com/5yyh8k9a
Ok, in 24 hours, more than 40 défense systems were revealed 🤩🤯🥳. Two different approaches, congratulations to all the authors! Amazing to see the role of mobile elements in these. Maybe as @epcrocha says, cells are just battlefields for MGE! So much cool biology to understand
Mapping the landscape of anti-phage defense mechanisms in the E. coli pangenome biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Primers are essential to #DNA replication, but how are they made? New work reveals the crystal structure of a primer initiation complex and shows that the catalytic domain of Prim-Pol enzymes is sufficient to start primer formation. @KZabrady @CisnerosRes ow.ly/Phqy50J1J1G
Latest research from the group of Aidan Doherty — Li / Zabrady et al. 'Molecular Basis for the initiation of DNA primer synthesis', now available on-line: Full article: nature.com/articles/s4158… Companion summary: nature.com/articles/d4158…
Congratulations to members of the Doherty laboratory @GDSC_Sussex on the publication of their latest study describing the molecular basis for the initiation of #DNA primer synthesis. Read more⬇️ nature.com/articles/s4158…
United States Trends
- 1. Thanksgiving 734 B posts
- 2. Tyrese Martin 1.438 posts
- 3. #AEWDynamite 24,7 B posts
- 4. Friday Night Lights 15,3 B posts
- 5. Druski 20,7 B posts
- 6. Kevin Hart 8.870 posts
- 7. Pat Spencer N/A
- 8. #Survivor47 4.325 posts
- 9. Knicks 13,2 B posts
- 10. Zuck 10,3 B posts
- 11. Vindman 59,2 B posts
- 12. #BillboardIsOverParty 136 B posts
- 13. Cruz Azul 18,6 B posts
- 14. Ace Bailey 1.185 posts
- 15. #ALLCAPS 1.170 posts
- 16. Izzo 1.314 posts
- 17. Trae Young 6.106 posts
- 18. Max Christie 2.144 posts
- 19. Jalen Williams 1.384 posts
- 20. Kuminga 1.910 posts
Who to follow
-
Kristina Schmidt
@Schmidt_Lab_USF -
Fernando Gomez-Herreros Lab
@FGH_Lab -
Angelo Taglialatela
@AngeloTagl -
Margarita Sobol
@MargaritaSobo20 -
Antony W. Oliver
@antonywoliver -
RosadoLab
@RosadoLab -
Marek Adamowicz
@MarekAdamow -
Nabieh Ayoub Lab
@ayoubnlab -
Kotaro Tsukada
@KotaroTsukada -
Ilona Kalasova
@IKalasova
Something went wrong.
Something went wrong.