Kouki Kawakami
@kk_kawakamiHEKato Lab (JSPS-PD, UTokyo) ← Asuka Inoue Lab (Tohoku Univ.) / GPCR
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I’m delighted to share my PhD work just published in @NatureComms! We uncovered a previously unanticipated hierarchical mechanism where specific G–protein subtype (Gq) governs GRK-subtype selectivity and its following β-arrestin functionality. nature.com/articles/s4146…
Delighted to share our paper out today as part of our BBSRC-funded collaboration with @warwickuni Here we describe how location of PGE2-driven cAMP signaling is critical for the human uterine endometrium to decode signals for decidualization. cell.com/iscience/fullt…
Structural insight into GPR55 ligand recognition and G-protein coupling | Cell Res doi.org/10.1038/s41422…
Structure basis of ligand recognition and activation of GPR55 | Cell Res doi.org/10.1038/s41422…
Wow!! Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch: Cell cell.com/cell/fulltext/…
👏 RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation: Cell cell.com/cell/fulltext/…
Now online! PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes dlvr.it/TFSQJT
BREAKING NEWS The Norwegian Nobel Committee has decided to award the 2024 #NobelPeacePrize to the Japanese organisation Nihon Hidankyo. This grassroots movement of atomic bomb survivors from Hiroshima and Nagasaki, also known as Hibakusha, is receiving the peace prize for its…
Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice insight.jci.org/articles/view/… おめです！ （学生時代のラボの先輩）
〈プレスリリース〉COX-1とCOX-2が紡ぐ妊娠初期の分子メカニズム～マウスモデルにおける着床過程の解明が示唆する新たな治療戦略の可能性～ jst.go.jp/pr/announce/20… 難治性不妊症である着床不全が起こる仕組みの1つを明らかにしました。 #JST #科学技術振興機構 #創発的研究支援事業
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Delighted to see this published in the BPPB @bpsjp Congratulations, Toshiki! "Four-color single-molecule imaging system for tracking GPCR dynamics with fluorescent HiBiT peptide", Yoda et al. doi.org/10.2142/biophy…
福島駅に警察官やSPっぽい人達がいっぱいいるとおもったらこれ🙄 【ライブ】「復興・創生」へ… 自民総裁選9候補が福島市で所見発表演説会｜FNNプライムオンライン fnn.jp/articles/-/759…
ラボメンバーの結婚式から帰宅。結婚式に参加したことはあれど主賓スピーチは初めてだったので柄にもなく少し緊張しました。しかし新婦側の主賓スピーチは慣れたものだったので、これも場数ということか。。 もちろん式自体は非常に良かったです。Fくん、お幸せに。素敵な家庭を築いてください。
👏 A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors. nature.com/articles/s4146…
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