@hebach_nr Profile picture

Nils Hebach

@hebach_nr

MD Student at @Winkler_Lab @dkfz interested in brain metastases and #cancerneuroscience

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Direct excitatory synapses between neurons and brain metastases, how cool is that?! #CancerNeuroscience Excited to have contributed to this stellar work led by the amazing @MA_Karreman and @VarunVenkatara2

We are exited to share our discovery of excitatory synapses between neurons and tumor cells in brain metastases of breast cancer & melanoma. The groundbreaking study co-led by @VarunVenkatara2 and me, with Thomas Kuner & @WinklerLab: biorxiv.org/content/10.110… #CancerNeuroscience



Nils Hebach Reposted

Preprint altert beyond brain tumors - Unique Programs of Cytotoxic T cells to amyloid plaques are adapted from microglia in a time dependent fashion with potential implications for therapy! Huge congrats to fantastic @julius_michel97 @KhwabSanghvi researchsquare.com/article/rs-514…


Nils Hebach Reposted

Thought provoking talks on the booming field of #cancerneuroscience & the promising new treatment approaches using existing drugs to modulate neuronal mechanisms #EANO2024 @wick_wolfgang @humsav @Winkler_Lab

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Nils Hebach Reposted

Today, during our labretreat, we can discuss our projects, progress and ideas for the future! Very productive and even more fun 🥳. #cancerneuroscience

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Nils Hebach Reposted

What if you could find out the history of signaling activity in each cell with a single round of imaging? Wouldn't that be incredible? Well, we thought so too. And that's what we set out to achieve with INSCRIBE in our new preprint. Let’s dive in! 🚀🔬 biorxiv.org/content/10.110…


Nils Hebach Reposted

Which route do T cells take to melanoma brain tumors? We uncovered that T cells target melanoma brain tumors through ICAM-1 expressing peritumoral venous vessels. The paper is now online @ImmunityCP sciencedirect.com/science/articl… For a summary 🧵 see 👇

How do T cells reach melanoma brain tumors? Using in vivo microscopy, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels. Our newest paper is now online @ImmunityCP authors.elsevier.com/sd/article/S10… A 🧵👇



Nils Hebach Reposted

How do T cells reach melanoma brain tumors? Using in vivo microscopy, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels. Our newest paper is now online @ImmunityCP authors.elsevier.com/sd/article/S10… A 🧵👇


Nils Hebach Reposted

Congrats to @valientelab !!🧠💥 Happy to be part of this outstanding work on astrocyte role in #brainmetastasis with interesting related translational applications!

1/13 In our new @CD_AACR paper we report an improved strategy to apply immunotherapy to brain metastasis, specially to those that are symptomatic, which has been reported to poorly respond to immune checkpoint blockade antibodies. aacrjournals.org/cancerdiscover…



Nils Hebach Reposted

Big news! The fly connectome is featured on the cover of a special edition of Nature. This is all possible thanks to the collaboration of 292 members of The FlyWire Consortium! nature.com/immersive/d428… Check out the thread for an overview of the 9 #flywire papers published today

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Nils Hebach Reposted

Excited to share some of what we have been up to since the pandemic began! #cancerneuroscience @CSHL @biorxivpreprint The first pre-print for the lab: biorxiv.org/content/10.110… A "tweetorial" will come with the final paper, but I want to...(1/2)


Nils Hebach Reposted

Great collaborative study with @Prevedel_Lab led by @StellaSoyka @MarcCSchubert @AmrTamimi9! This technology platform will help us investigate brain tumors where they intermingle with white matter fibres and are hard to detect. See here how we can fly through the cortex and reach…



Nils Hebach Reposted

🚀 Just attended an insightful talk by @MA_Karreman on "Cancer Networks in Brain Metastases"! 🧠🔬 She explored targeting brain metastases preventatively and how the microenvironment affects tumor growth and immune surveillance @DKFZ #BrainMetastases #NGIFreiburg

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Nils Hebach Reposted

Thrilled our paper on GABAergic neuronal lineage development and targeting in H3G34-mutant glioma is now out in @Cancer_Cell! Check out this 🧵 by @Gavcruzeiro👇

Our recently published manuscript in Cancer Cell – Diffuse hemispheric glioma, H3G34R/V-mutant (H3G34-DHG) - cell.com/cancer-cell/fu…

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Nils Hebach Reposted

🚨❗️🚨 New Paper Alert My postdoctoral work now out in @Nature We find that sensory neurons drive breast cancer metastasis via an activity-dependent paracrine signalling mechanism mediated by substance-P, extracellular ssRNA & TLR7 receptor. (1/11) urldefense.com/v3/__https://w…$ 🧵👇🏾

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Nils Hebach Reposted

🚀 Excited to share our latest research! We’ve observed significant effects of TTFields on tumor microtube formation and tumor cell network integrity in vitro. Stay tuned as we move to verify these effects in vivo... To be continued... pubmed.ncbi.nlm.nih.gov/39088157/


Nils Hebach Reposted

CSF liquid biopsy for glioma classification. bit.ly/3WrFWJ9

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Nils Hebach Reposted

📣You can still register for tomorrow's Cancer Neuroscience Virtual Seminar, from 5-6 PM CEST, by Chong Liu: Decipher the roadmap of gliomagenesis. Don't miss it! us06web.zoom.us/meeting/regist…


Nils Hebach Reposted

The NGI team is excited about the upcoming "Cancer Meets Neuroscience" session and @MA_Karreman's talk on "Cancer Networks in Brain Metastases." Join us for insightful discussions! @Uniklinik_Fr @uniklinik_hd @CancerNeurosci1 @Winkler_Lab

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Nils Hebach Reposted

Paper alert 📚 Neural progenitor–derived Apelin controls tip cell behavior and vascular patterning Excited to share my PhD's work, many thanks to all members of the @HelkerLab Lab and @Kazebrafish and @BenjaminHogan13 for the help! science.org/doi/10.1126/sc…

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Nils Hebach Reposted
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