Thanvi Srikant
@ThSrikantPostdoc @KBomblies lab (ETH Zürich), former PhD student @PlantEvolution lab (MPI Tübingen). Epigenomics, natural variation & polyploid evolution in plants 🌱
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What are the immediate consequences of genome doubling on chromatin accessibility & transcription, and how do these change over evolution? Read our latest paper in @MolBioEvol to find out! Big shoutout to co-authors @KBomblies and @AdriGonzalo ✨ [1/6] academic.oup.com/mbe/advance-ar…
It is my absolute pleasure to share my incredible postdoc Dawei's @amaizeingcorn manuscript on epigenetics and aging in Arabidopsis. It is the work I am most proud of thus far in my career, and every figure has a breakthrough that we are excited about biorxiv.org/cgi/content/sh…
Our latest research on position-dependent transcriptional regulatory sequences in plants is now published! 🌿 More details in our preprint tweet and in this thread! 👇 nature.com/articles/s4158… 📄🔍 (1/5)
Transcription regulation in plants vs. animals - same-same or different? We show in a new preprint that in plants, regulatory sequences next to the TSS are position-dependent - as opposed to animal enhancers which are position-independent (1/6) biorxiv.org/content/10.110…
We present a manuscript in which we describe the genetics of natural variation in the ploidy of A. lyrata from the White Sea to the Bering Strait, resequencing whole genomes of > 400 A. lyrata from herbarium and seed collections. biorxiv.org/content/10.110…
Excited to see our peer-reviewed work on recurrent horizontal mini-chromosome transfer in the blast fungus now out! ✨ academic.oup.com/mbe/advance-ar… Thanks team 🌈 @smlatorreo @ThorstenLangner @KamounLab @hernanaburbano @YuSugiharaY @joewinnz @Adeline_Harant @AngusMalmgren
🧬Excited to share our latest pre-print! We've developed a rapid eQTL analysis approach using single-cell/nucleus RNA sequencing of Arabidopsis pollen nuclei. This method uncovers cis- & trans-eQTLs, including a master regulator of sperm cell development! 🌱📊 #PlantScience #eQTL
Expression quantitative trait locus mapping in recombinant gametes using single nucleus RNA sequencing biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
So proud of my lab for our latest work out today in @Naturepub We took advantage of transposable elements and CRISPR to perform targeted insertion of cargo DNA in the Arabidopsis and soy genomes. Led by @mcliupeng nature.com/articles/s4158…. 🧵
My first ETH PhD student, Amrita Möhl-Raj, graduated & did a great job! At the Apero, a reunion of some ex-Weigel folk (@PlantEvolution) - former technician (me), former postdoc Francois Parcy (@Francois_Parcy) and former PhD student, now Postdoc here, Thanvi Srikant (@ThSrikant)
🧬Transposable elements are intriguing auto-replicative genomic units. But how do they encode the factors necessary for mobilization? How are they regulated? how do they evolve?🤔. Excited to share our latest research addressing these questions! doi.org/10.1101/2024.0….🧵
Grateful to @KBomblies and all co-authors for the opportunity to be a part of this cool project! We describe how pollen tube growth is defective in new polyploids & reduces their fertility, and how naturally evolved polyploids find a solution to overcome this challenge
Thrilled to announce - our latest on polyploid arenosa just got published in Science :-) Thanks to the amazing team that made it happen including @Thsrikant and @AdriGonzalo!! And thanks reviewers for enthusiasm, especially reviewer 1, whoever you are! science.org/doi/10.1126/sc…
Excited to share our latest work 'Multiple horizontal mini-chromosome transfers drive genome evolution of clonal blast fungus lineages' biorxiv.org/content/10.110… @smlatorreo @AngusMalmgren @Adeline_Harant @joewinnz @YuSugiharaY @hernanaburbano @KamounLab @ThorstenLangner (1/9)
A perfect snowy morning in Les Diablerets to conclude the SwissPLANT Early Career Meeting and conference. Excellent talks in diverse topics of plant science, and a very welcoming academic community! :)
1/6 Happy to see the final chapter of my PhD thesis now published in @G3 -> "Deleterious Phenotypes in Wild Arabidopsis arenosa Populations Are Common and Linked to Runs of Homozygosity" academic.oup.com/g3journal/adva… [a thread]
1/ Blast season in Europe has started!! twitter.com/TheSainsburyLa… bio.mpg.de/292621/news
6/ We need YOUR help! The blast season is in full swing right now. Tweet your photos #EuroBLAST if you you see any blast symptoms. Contact: @Cristina tsl.ac.uk/about/people/c…
Very excited to have been awarded my first postdoctoral fellowship, to study chromatin architecture dynamics during adaptation to polyploidy :) Thanks to @KBomblies, Bomblies lab members and @PlantEvolution for their support! snf.ch/en/nZYE5j2PuX7…
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