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@Xiaojie_Qiu
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7 years ago, I met a junior fellow named @JD_Buenrostro who blew me away with a vision of futuristic genomic technologies Today, we (@ajaylabade31, @carolinecomenho) are excited to share our first steps into that future: Expansion in situ genome sequencing 1/
🎧 New episode! This time on The Climate Biotech Podcast, Homeworld Collective co-founders @D_R_Goodwin and @PaulReginato sit down with the legendary @geochurch A pioneer in genomics and synthetic biology, George is known for his innovative visions for future tech — and for…
We’re excited to share our latest computational method, TissueMosaic, for comparative analysis of spatial transcriptomic datasets across conditions! (1/5) biorxiv.org/content/10.110…
Happy to share our new work describing DESynR genes! The evolution of new human protein-coding genes relies on repurposing protein domains from ancestral genes, rather than de novo sequence creation. New genes evolved from old parts, and while we have methods that enable…
Can we make Acoustic Proteins with different "colors" the way the developers of GFP made BFP, YFP, etc?🌈 Yes, via #directedevolution of #gasvesicles! Congrats to @nivinnystrom et al on the first GVs multiplexed based on nonlinear response to ultrasound. biorxiv.org/content/10.110…
Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!
strongly agree that we have to build better measurement technologies for this whole ~virtual cell~ thing to work
How can we condense 50-100 years of biological progress into 5-10 years? I wrote a response to @DarioAmodei's essay, "Machines of Loving Grace." Most bottlenecks slowing biology today, I argue, are biophysical rather than computational. LEVERS FOR BIOLOGICAL PROGRESS🔻
I have exciting news!🌟 In Jan 2025, I will begin my position as an Assistant Professor at @UTHealthSPH in the Center for Human Genetics & Department of Epidemiology :) I'm hiring at all levels, so please send your trainees my way!! More info at heylab.org 🧬
If you stick with me, we're gonna accomplish great things, Morty! And together we're gonna run around, Morty, we're gonna do all kinds of wonderful things, Morty. Just you and me, Morty. We're the only [blerggghrr] friends we've got, Morty. It's just Rick and Morty. Rrrick and…
The DelRosso Lab is starting @UCSF 1/2025 and is seeking applicants for a research postbac! We will be developing cutting edge high-throughput approaches to study the relationship between disordered protein interactions and transcription in human cells🔎 aprecruit.ucsf.edu/JPF05341
Excited to share this collaborative effort with @dianyang1117 & @MattG_Jones, combining Cas9 evolving lineage tracing and spatial techniques to study lung cancer evolution. Great supports from @insitubiology, @JswLab & @YosefLab biorxiv.org/content/10.110…
sure sequencing and UMAPs reveal heterogeneity, but microscopy lets you actually see it 🤩
1/9 Insanely PROUD to share our new collaborative project with @Dey_Gautam & @CentrioleLab #PlanExM We think (almost certain) #Expansion #Microscopy (#UExM) is a turning point for #Protistology and #Cell Biology. 🔗 [tinyurl.com/PlanExM1]
We have a new preprint (biorxiv.org/content/10.110…)! I’m excited to introduce our latest deep learning model, Decima. More in this thread:🧵 1/14
this looks incredibly wild (and fun)
Can we invent new brain-computer interface modalities? @raffi_hotter and I got 9 friends together and built a lab at home to test two totally new imaging methods: acoustoelectric imaging & functional ultrasound through the skull 🧵 story that involves nV measurements, pretty…
What if you could find out the history of signaling activity in each cell with a single round of imaging? Wouldn't that be incredible? Well, we thought so too. And that's what we set out to achieve with INSCRIBE in our new preprint. Let’s dive in! 🚀🔬 biorxiv.org/content/10.110…
Our paper on continuous mutagenesis in living cells using HACE is now out in @ScienceMagazine! We now demonstrate that HACE continuously generates mutations over a 10-day period and enables targeting using dCas9 without introducing DNA nicks. science.org/doi/10.1126/sc…
The Boyden lab has developed a new ExM technique that makes it possible to expand tissue 20-fold in a single step. This simple, inexpensive method could pave the way for nearly any biology lab to perform nanoscale imaging. mcgovern.mit.edu/2024/10/11/a-n…
Thrilled to see our ExIGS tool featured! A true testament to the power of collaboration. Huge congrats to the team for their hard work! 🧬@ajaylabade31 @z_chiang @CarolineComenho nature.com/articles/d4158…
it's crazy how non-model organism talks make everyone happier and more creative and genuinely excited about science 🥹
On a day filled with interesting news, this stands out: People justify our current science ecosystem by saying that it lets the cream to rise to the top, but this is statistical evidence that increasing accessibility will impact scientific achievement at the highest levels
What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you need the right family too? And why should we care? A 🧵 on our paper on the Nobel Laureates. A teaser: the income distribution of the laureates' fathers.1/N
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Arjun Raj
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Rong Fan
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dana_peer
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