@PgGarcialab Profile picture

Garcia lab

@PgGarcialab

Stem cells and genome stability, DNA damage, cancer, adult stem cells, iPSC, leukaemia, MDS, MYBL2

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Garcia lab Reposted

I have two PhD projects listed on this scheme - please get in touch if you are interested!

🔍 Applications are now open for the 2025 PhD cohort! Successful applicants will receive full funding in addition to a stipend at the standard UKRI rate, with an opportunity to carry out an industry placement and access to high-quality mentorship across six partner institutions.

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Garcia lab Reposted

PhD position available! We have a position available as part of the @MIBTP_BBSRC programme (warwick.ac.uk/fac/cross_fac/…)on epigenetic regulation of stem cell fate in collaboration with the Cowley lab @uniofleicester Deadline for applications - 16th January 2025 Please share!


Garcia lab Reposted

Job alert: Interested in pancreatic beta cells, a dash of genomics and novel treatment options for diabetes? We are looking for a post-doc!! Contact us for an informal chat! edzz.fa.em3.oraclecloud.com/hcmUI/Candidat…


Garcia lab Reposted

Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

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Garcia lab Reposted

🚨 Great alternatives to BioRender are now available!! 📢 @NIAIDNews offers a collection of public figures and icons for everyone to use. Check it out at bioart.niaid.nih.gov

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Garcia lab Reposted

I haven’t posted much since Twitter is X, but I have a good reason today☺️ if you like #cancerstemcells #stemcells and #immunotherapy, this is for you! With partner in crime Phoenix Miao😎 nature.com/articles/s4156…


Garcia lab Reposted

Excited to share this collaborative effort with @dianyang1117 & @MattG_Jones, combining Cas9 evolving lineage tracing and spatial techniques to study lung cancer evolution. Great supports from @insitubiology, @JswLab & @YosefLab biorxiv.org/content/10.110…


Garcia lab Reposted

Updated manuscript! We analyzed Cas9-generated indels at >2,800 synthetic Cas9 targets in 18 DNA repair deficient stem cell lines to learn about sequence-specific DNA repair. #GeneEditing #Cas9 #DNArepair Soon to be out! biorxiv.org/content/10.110…

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Garcia lab Reposted

#singlecell epigenomic technologies are redefining our understanding of cancer evolution. Now, @MartheLaisne, @MatLupien & @VallotCeline explain how epigenomic heterogeneity drives tumor cell state diversity through reprogramming and selection. go.nature.com/3NyflWN

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Garcia lab Reposted

Congrats Julia Phan + Aslan Tasdogan for their paper in Science today: hematopoietic stem cells (HSCs) & erythropoiesis get activated during pregnancy and after bleeding by retrotransposons that turn on in HSCs activating cGAS/STING & interferon signaling science.org/doi/10.1126/sc…


Garcia lab Reposted

Happy to see our collaborative paper with Cyrus Vaziri’s lab demonstrating that RNF168 is recruited to damaged replication forks via a degenerative PIP box and its MIU1 ubiquitin binding domain is finally out in @NAR_Open : academic.oup.com/nar/advance-ar…


Garcia lab Reposted

🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)


Garcia lab Reposted

Want to do a DPhil @BiochemOxford ? Here is a link (bioch.ox.ac.uk/graduate-about…) to programmes that admit students. Great labs to choose from. Have a look at kloselab.co.uk if you want to know more what we do in my group! Please RT!

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Garcia lab Reposted

📢 We are on the lookout 👀 for a PhD candidate! Fully funded 4-year project focused on the molecular dynamics of replication stress sensing at the replisome core. Please RT 🙏🏻 !

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Garcia lab Reposted

Interested in the functional architecture of replication fork protection?  Check out our training programme JAEINT24_EX0551 and find out about essential mechanisms counteracting cancer onset. Contact us to learn about our research project and international environment!

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Garcia lab Reposted

I am seeking an enthusiastic postdoc to join my lab in Sydney to work on Nuclear Dynamics, DNA repair and genome stability. We offer innovative science, a competitive salary, and a supportive team. If you are interested, please get in touch with me: nlamm-shalem@cmri.org.au


Garcia lab Reposted

1/2 We have just advertised a post-doc position, looking for someone to investigate how DNA replication and repair -dependent processes influence haematopoietic stem cell longevity & plasticity, & counteract DNA damage-dependent clonal haematopoiesis: nature.com/naturecareers/…


Garcia lab Reposted

A paper in @Nature reports the ageing effects of a pro-inflammatory protein called IL11 in mice. Inhibition of this protein is shown to improve the health of old mice and increase their lifespan. go.nature.com/3WqC0JX

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Garcia lab Reposted

An MRC-funded 3 yr postdoc position is available in the Humphrey lab at the Genome Damage and Stability Centre, University of Sussex, to target chromatin defects in cancer. Please repost and DM if interested. tinyurl.com/yw4kk75b @sussexLifeSci @ukgsn @OxfordCancer

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Garcia lab Reposted

Excited to share the latest discovery of the Carlomagno lab!!! Spearheaded by Megha Karanth. 🥳 @ScienceAdvances The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain | Science Advances science.org/doi/abs/10.112…


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