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@AML_Hub
@charliecraddock
@drpramilak
@DrLornan
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@ProfBMT
@DeeptiRadia
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@pvyas_oxford
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Yet another failed randomized trial of HMA combination in higher risk #MDSsm, this time with RARA agonist tamibarotene: n=245, CR rate 23.8% with combo vs 18.8% HMA alone, p=0.20. This is becoming a depressing and recurring theme, @Dr_AmerZeidan ir.syros.com/press-releases…
Data-driven, harmonised classification system for MDS sciencedirect.com/science/articl… It took a global effort for this project using largest MDS cohort to date from Moffitt and Genomed datasets. Thx to all my dear coauthors @MoffittNews @Dr_AmerZeidan @drsomedeb @genomed4all @ic_MDS
Many congratulations to my colleague @mikewdennis on your award of an honorary chair @OfficialUoM Long overdue and richly deserved. New door sign needed Prof Mike! 👏👏
Congratulations to the new Honorary Clinical Chairs appointed by Manchester Academic Health Science Centre for 2024. These positions are awarded to individuals who have made a major contribution to their clinical specialty, including excellence in research and education. Read…
Your opportunity for on-demand viewing of the Sessions from the 2024 AAMDSIF Bone Marrow Failure Scientific Symposium awaits! Follow this link for all the sessions: cvent.me/mQOXMZ
More from @jadothm et al re NPM1m AML getting intensive therapy! -FLT3-ITD, DNMT3A, WT1, non-ABD NPM1 assoc w/ MRD+ & worse OS (all but FLT3-ITD assoc w/ relapse in MRD- dz) -difficult to identify groups benefiting from allo when NPM1 MRD- post 2 cycles sciencedirect.com/science/articl…
🌟 Meet Maria, Chair of @PNHSupport and leader in patient advocacy. From NZ to UK, she champions PNH patients' rights. She founded PNH Global Alliance and is also an @eupatients graduate, dedicated to healthcare research & empowering patients. #MeetMaria #PatientAdvocacy🌍
Reporting variants, a must know in 2024 #EBMT24 @TheEBMT_Trainee @TheEBMT
Great panel discussion at the @aamds anniversary summit on the merits of immunosuppressive therapy and stem cell transplant in #SAA. #BMFsm @bhavishap29 @AustinKulasekar @AmyDeZern
Thanks for the invite. Enjoyed the discussions with colleagues and a stalwart like Dr Deeg @aamdsif
Amy DeZern Moderates the panel on "Moving the Needle: Alternative Donor BMT" with H. Joachim Deeg, Austin Kulasekararaj, and Bhavisha Patel at #AAMDSIF40th
Amazing journey into history of marrow disease #AA #MDS #PNH by the great haem historian @DavidSteensma at @aamdsif It was a joy watching you dwell into history @MikkaelSekeres
I look like I am pleading for something… better treatments for marrow failure disorders. Thanks @aamdsif for the invitation to present the keynote address today on the history of our understanding of bone marrow, in honor of the Foundation’s 40th year (& 100 research grants.)
Professor David Rees at the launch of the Lancet Haematology Commission on Sickle Cell Disease at the Houses of Parliament. A very proud moment for our lab! Congrats to all authors @DavidRe40855993 @KCLcancer_pharm
Thanks @LeukUK for the shoutout 📣 please do get in touch- we’d love to hear from you! @mikewdennis @pvyas_oxford @charliecraddock
📢 Are you a patient or carer with lived experience of AML? Have you been treated with Venetoclax and Azacitidine? Researchers are developing a new clinical trial and they need your input! Interested? Please send your contact details to lewis@leukaemiauk.org.uk by 31 October.
I have a challenging case of paroxysmal nocturnal hemoglobinuria so I am reading about it (a lot). ABIM doesn't trust doctors to do this so they make us pay them money for fake MOC certification. Excellent free review on PNH! onlinelibrary.wiley.com/doi/full/10.10…
Ana Rio-Machin and Kevin Rouault-Pierre will use the award to decipher the role of #germline variants in the RNA-helicases to improve the #EarlyDetection and management of familial myelodysplastic syndrome and acute myeloid #leukaemia [4/8]
Very sad indeed #MDS @ukmdsforum an eternal curse for high risk MDS #tp53 with futility of number of Ph3 trials in MDS @Dr_AmerZeidan
This is a huge blow for the #MDSsm field, but another reason why people should be more cautious about reading too much into phase 1 trials before randomized data. Gilead To Discontinue Phase 3 ENHANCE Study of Magrolimab Plus Azacitidine in Higher-Risk MDS investors.gilead.com/news/news-deta…
Succinct. At Breaking Point or Already Broken? The National Health Service in the United Kingdom | NEJM nejm.org/doi/full/10.10…
What a gifted speaker !!! @AustinKulasekar speaking about pathophysiology and clinical management of extravascular hemolysis in #PNHsm at #EHA2023
Very proud to listen to Jens Panse of @UniklinikAachen @RWTH presenting the phase 1 data of the MASP-3 inhibitor OMS906 in patients with #PNH at #EHA2023 ! Great job, Jens ! #cioabcd
Our dedicated clinicians explaining past to present in #PNH care & treatment from significant survival risk to life saving treatment with #unmetneed. BUT not all patients have #access still @ERNEuroBloodNet @AustinKulasekar @lichterzellen #EHA2023
@AustinKulasekar on management of BTH in PNH. Great talk on the #ipigconference
United States Trends
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Who to follow
-
AML Hub
@AML_Hub -
Charlie Craddock CBE
@charliecraddock -
Pramila Krishnamurthy
@drpramilak -
DrDonalMcLornan
@DrLornan -
vp
@vicpotter123 -
Antonio Pagliuca
@ProfBMT -
Dr Deepti Radia
@DeeptiRadia -
Priya Sriskandarajah 🇺🇦💙💛
@PriyaSriRajah -
paresh vyas
@pvyas_oxford -
Michelle Kenyon💙
@michellekenyon5 -
Varun Mehra
@docbmt -
Emma M. Groarke
@emmamgroarke -
Adele Fielding
@AdeleKFielding -
PNH Global Alliance
@GlobalPnh -
ASCENT - Accelerated Stem CEll traNsplant Trials
@crctuASCENTteam
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