Nadav Ahituv
@NadavAhituvProfessor, Department of Bioengineering and Therapeutic Sciences, Director, Institute for Human Genetics, UCSF
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Updated VISTA Enhancer Browser, 7 years in the making, out in @NAR_Open! >4,500 transgenic in vivo enhancer experiments for all your developmental biology, human variation and #evodevo needs. enhancer.lbl.gov #enhancers #embryos doi.org/10.1093/nar/gk…
1/🧵Excited to re-introduce Memento in (cell.com/cell/fulltext/…), a scalable method for differential analysis of scRNA-seq data. It provides first-in-class performance in statistical power and calibration for comparing differences in mean, variability, and gene correlation.👇
Thinking about a PhD using computational power to answer pressing problems in biology and health? @UCSF Biological and Medical Informatics PhD program is recruiting for Fall 2025! Join our info session next Monday Oct 21: bmi.ucsf.edu/admissions.
Very cool work by @YinShenLab showing how allelic compensation can be used as a regulatory compensation mechanism. biorxiv.org/content/10.110…
Beautiful work by @KarissaLHansen and @ElphegeNoraLab on the role of cohesin in enhancer-promoter interactions. Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function biorxiv.org/content/10.110…
Beyond stoked to share our latest, entitled “Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording” ! biorxiv.org/content/10.110…
Incredibly proud to share that I recently joined @UCSF_BTS @UCSF as an Assistant Professor! This means that the Calderon Lab is now open! Or, more accurately, in the process of opening as I am still unboxing equipment and unraveling giant posters (a last @JSHendure lab gift) 🥳
Check out our recent preprint, co-led by two former PhD students in the lab @dcsoto_cl and @jmuribescr, in which we identify and characterize human duplicated genes implicated in brain evolution. biorxiv.org/content/10.110… /1
Upping this faculty position in our department @UCSF - we welcome applications from any quantitative biologist, especially those interested in AI/ML or creating AI/ML-ready datasets! Deadline Oct 3rd - link to apply: aprecruit.ucsf.edu/JPF05232
🔔🔔🔔FACULTY POSITION IN OUR DEPARTMENT @UCSF 🔔🔔🔔 We are scientifically diverse, spanning a huge range of basic sciences! Bioengineering, Computational Biology, Drug Development Sciences, Molecular Design, Systems Pharmacology, ANYTHING QUANTITATIVE! aprecruit.ucsf.edu/JPF05232
It was a lot of fun doing this! Thanks so much @patrick_j_short for hosting me!
Episode 152 of #TheGeneticsPodcast is live 🚀 @NadavAhituv, Director for the Institute of Human Genetics @UCSF talks the history of the non-coding #genome and the power of #CRISPR. Listen now: 🎧 link.chtbl.com/EP152?sid=X 📽️ youtu.be/PhYZ89d9oT4 #SanoGenetics #Genetics
Our paper describing a scalable method for Multiplex, single cell CRISPRa screening for cell-type specific regulatory elements is now published! rdcu.be/dUnoq nature.com/articles/s4146…
Exceptionally stoked to share our new work entitled “Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements” ! biorxiv.org/content/10.110…
Thank you to @KathyGiacomini, Christof Fellmann, David Schaffer, Francine Gregoire, @M_Kyle_Cromer, Emil Kakkis, Andrew Carroll, David Kelley, Danny Wells, Tony Capra, Christina Fan, Andrew Farmer, Wenjun Ouyang, and @YinShenLab for their outstanding 2024 IHG Symposium talks!
An experimental census of retrons, now published in @NatureBiotech We synthesized more than a hundred new retrons and put them through their paces, improved recombineering rates and precise editing in human cells up to 40%. nature.com/articles/s4158…
We are recruiting two computational biologists/bioinformaticians with ML expertise and a focus on genomics, variant effects and gene regulatory sequences in staff scientist and postdoc roles in Lübeck, Germany. Please find details here: kircherlab.github.io/contact.html
Excited to share the white paper for the IGVF Consortium, supported by @genome_gov Deciphering the impact of genomic variation on function rdcu.be/dSZdm
Understanding the function of an entire genome is no easy task! Most genes likely have more than one function. To understand the functional effects of genomic variation, NHGRI launched a consortium called Impact of Genomic Variation on Function (IGVF). genome.gov/news/IGVF
🔔🔔🔔FACULTY POSITION IN OUR DEPARTMENT @UCSF 🔔🔔🔔 We are scientifically diverse, spanning a huge range of basic sciences! Bioengineering, Computational Biology, Drug Development Sciences, Molecular Design, Systems Pharmacology, ANYTHING QUANTITATIVE! aprecruit.ucsf.edu/JPF05232
The application consists of an NIH-biosketch, ~2 page future research vision, teaching/mentoring statement, and contributions to diversity statement. No cover letter, past research, pdfs of preprints/papers, bespoke CV format needed! We will request letters for our shortlist.
Four last days to register! Symposium on 9/9. We have a great lineup of speakers, plenty of time to network and registration is free. genotech.ucsf.edu/home
Another beautiful story by Ari Daniel (@mesoplodon) @NPR on the Belize bat-a-thon and our work on how fruit eating bats can eat so much sugar and not get diabetes. Amazing work by @GreatWeiShark and Mai Nobuhara! npr.org/sections/goats…
Thrilled to share that I'll be starting a tenure-track assistant professor position at the Department of Genetics, Washington University in St. Louis, in January 2025! @WashUGenetics I am recruiting lab members at all levels. For more details, visit our lab website or check flyer
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