Hyejung Won
@hyejung_wonAssociate Professor, Genetics/Neuroscience, University of North Carolina, Chapel Hill
Similar User
@PGCgenetics
@WrayNaomi
@alexisjbattle
@tuuliel_lab
@NadavAhituv
@mikejg84
@be_stranger
@hakyim
@SVergult
@yuchaojiang
@DPosthu
@anshulkundaje
@PhilpotLab
@choekatr
@AkisPapantonis
Here’s to the end of our first in-person meeting of the @pgc_fg working group at #WCPG2024. Thanks to all participants and my co-chair @MLynall! Very exciting updates and new plans made for leveraging @PGCgenetics data to increase our understanding of psych disorders.
Today we introduce human neural loop #assembloids created from 4 parts derived from stem cells to study the cortico-striato-midbrain-thalamo-cortical pathway and to model neurodevelopmental disease Work led by the remarkable Ji-Il Kim and Yuki Miura in the lab. Also in…
Glad to share the peer-reviewed version of the @mgheffel manuscript now in @Nature In collaboration with @lab_paredes , we studied the chromatin conformation and DNA methylation changes during human hippocampus and frontal cortex development. nature.com/articles/s4158…
The theoretical physics approach to neural nets was launched by @HopfieldJohn in this classic 1982 paper that introduced the "energy function" to associative memory models. pnas.org/doi/abs/10.107…
Doing good science is 90% finding a science buddy to constantly talk to about the project.
Another phenomenal piece of work from a superstar postdoc and my closest collaborator @TroyMcDiarmid, & incredible (now PhD student!) Megan Taylor! Megan joined the lab as a freshman undergrad, & it has been nothing short of amazing watching her develop into an amazing scientist.
Beyond stoked to share our latest, entitled “Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording” ! biorxiv.org/content/10.110…
A monumental moment in the history of psychiatric disorders drug development. A new promising drug for schizophrenia treatment after a really long time. FDA approves Bristol Myers Squibb's KarXT for the treatment of schizophrenia. So excited about this news.…
"Although [whole genome sequencing] results in an approximately fivefold increase in the total number of assayed variants over [exomes + imputation], the number of detected signals differed by only 1% ..." nature.com/articles/s4158…
First pre-print from the lab! Together with @lucapinello and @danielevanbauer we developed CRISPR-CLEAR, an experimental and computational pipeline to dissect enhancers at nucleotide resolution. biorxiv.org/content/10.110…
Come on in and join us ! @KonradWagstyl and I have a fully-funded 4 yr PhD-ship open thru the super NIMH-UCL (D.C/London) graduate program partnership (shorturl.at/Qr5uq). Bridge Macro<-> views of 🧠 wt neuroimaging & omics (e.g. shorturl.at/W2cgo). Pls DM/apply ! 😃
What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back @Nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design
Excited to share the white paper for the IGVF Consortium, supported by @genome_gov Deciphering the impact of genomic variation on function rdcu.be/dSZdm
Understanding the function of an entire genome is no easy task! Most genes likely have more than one function. To understand the functional effects of genomic variation, NHGRI launched a consortium called Impact of Genomic Variation on Function (IGVF). genome.gov/news/IGVF
Epigenome editing is transforming biological sciences and medicine. We're grateful for the opportunity to publish this review of the field in @NatureBiotech Check it out here: rdcu.be/dPjsJ
Each day finished with a round table. Discussions were lively, and fascinating. I believe we successfully left with a better idea of each other’s perspectives, and some idea of what needs to be done in the years ahead! Thanks to all the amazing attendees and invited speakers!
@hyejung_won presented her labs work at the molecular level, investigating the specific mechanisms related to genes associated with various mental disorders
Last week, with Marco Del Giudice and @emanuele_espo98 we hosted a workshop in Erice, Sicily: ‘Bridging evolution and genetics’ to understand mental disorders. It exceeded our expectations! I’ll run through the presentations…
The PGC Functional Genomics workgroup serves as a dynamic hub for collaborative, open discovery science and scalable method development. We aim to understand how genes, cells and molecules impact the symptoms and course of psychiatric disorders in populations globally.
New paper on single-cell genomics & regulatory networks for 388 human brains just out in @ScienceMagazine Neat stuff on single-cell QTLs, cell-to-cell communication, & DL models simulating drug effects (science.org/doi/10.1126/sc…) #PsychENCODE24
United States Trends
- 1. #UFC309 302 B posts
- 2. Jon Jones 175 B posts
- 3. Jon Jones 175 B posts
- 4. Jon Jones 175 B posts
- 5. Chandler 88,2 B posts
- 6. Oliveira 72,5 B posts
- 7. Kansas 23,1 B posts
- 8. #discorddown 6.848 posts
- 9. Bo Nickal 9.033 posts
- 10. Do Bronx 11,1 B posts
- 11. ARod 2.170 posts
- 12. #BYUFootball 1.404 posts
- 13. Rock Chalk 1.416 posts
- 14. Dana 261 B posts
- 15. Tennessee 52,6 B posts
- 16. #kufball 1.105 posts
- 17. #MissUniverse 438 B posts
- 18. Big 12 16,6 B posts
- 19. Keith Peterson 1.373 posts
- 20. Oregon 34,4 B posts
Who to follow
-
PGC Consortium
@PGCgenetics -
Naomi Wray
@WrayNaomi -
Alexis Battle
@alexisjbattle -
Lappalainen Lab
@tuuliel_lab -
Nadav Ahituv
@NadavAhituv -
Michael Gandal
@mikejg84 -
Dr. Barbara Stranger
@be_stranger -
Hae Kyung Im 任慧耕 임혜경
@hakyim -
Sarah Vergult
@SVergult -
Yuchao Jiang
@yuchaojiang -
Danielle
@DPosthu -
Anshul Kundaje (anshulkundaje@bluesky)
@anshulkundaje -
Ben
@PhilpotLab -
Katrina Choe
@choekatr -
Akis Papantonis
@AkisPapantonis
Something went wrong.
Something went wrong.