Eva Kowalinski
@KowaEvaGroup leader @embl. Curious how #RNA #modifications affect function. Using #biochemistry, #Xraycrystallography and #cryoEM to find out. Climbing mountains.
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+++ new preprint alert +++ We reveal the architecture of the #trypanosomatid RNA cap-binding complex (CBC) and probe its SL RNA binding properties. Does it bind the uniquely modified cap4 structure? --> read our preprint: biorxiv.org/content/10.110… #RNA #RNAcap #NTDs #cryoEM
Welcome to Day 1️⃣ of #EMBLInfectionBiology! EMBL Conference 'The next generation in infection biology' is a platform for late-stage postdoctoral scientists to present their work and connect with the leading institutions in #infectionbiology 🧑🏻🔬 Two days of exciting fully virtual…
Starting now 🟢 Session 1: Pathogen biology' chaired by Sebastian Baumgarten (Institute Pasteur) and Eva Kowalinski (EMBL Grenoble) 🦠🎙️Live: 'Interspecies interactions modulate pathogenicity-associated phenotypes of Clostridioides difficile' presented by Stephan Kamrad…
We close out the Grenoble CryoEM club @EMBLGrenoble @IBS_Grenoble with the Inauguration of a new Krios Microscope and an interesting trip down memory lane on the 'origins' of CryoEM and a look at molecular chaperones in a keynote lecture by Prof Helen Saibil from @BirkbeckUoL
A new article on Daisuke Kihara's research introduces DiffModeler, an automated method that enhances protein modeling accuracy and could transform large complex modeling. Read More: bio.purdue.edu/news/articles/… #PurdueBiology #Biology #PurdueScience #PurdueStaff #research
Thrilled to preview NeuralPLexer3 Beta (NP3 Beta), the next generation of AI structure biology model our team at @iambic_ai has been building. 🧵 :
Today we’re previewing NeuralPLexer3 Beta: demonstrating unprecedented accuracy and speed in predicting protein-drug complexes, with instant and accurate structural insights across the full range of protein classes and drug molecules. Learn more: iambic.ai/post/np3-previ…
New tool ARTEMIS for superposition od 3D #RNA structures and structure-based alignment 🙌 Congratulations to the Authors! academic.oup.com/nar/article/52…
Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov
RNA editing for future!
Genome editing has centered around DNA, with over 40 ongoing clinical trials and 2 FDA approvals. But RNA editing has some key advantages and appears to be taking off. An open-access review @ScienceMagazine science.org/content/articl…
AlphaBridge: tools for the analysis of predicted macromolecular complexes • AlphaBridge introduces tools to analyze and visualize the interfaces between predicted macromolecular complexes using data from AlphaFold3. It processes the predicted interactions into intuitive…
Much of the success of breakthroughs, such as AlphaFold, is thanks to a database of protein structures dreamed up in the 1960s by Helen Berman go.nature.com/4hp4UCP
Massive!!!
Excited to share our latest research on co-translational mRNA decay by the exosome in human cells! We uncover how the exosome-SKI complex is recruited to ribosomes and propose a novel role for SKI in recognizing collided disomes. @MPI_Biochem 👇👇👇
It's RNA again🎉 For the second year in a row, the Nobel Prize in Physiology or Medicine honors RNA research. Huge congratulations to the winners from @EMBL_RNA_Club on this well-deserved achievement! #RNA @embl
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Welcome back! VEuPathDB resources are back online today! We will continue to provide bioinformatics services under a new organizational structure. Read more here: veupathdb.org/veupathdb/app/…
Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. @befcorreia @sokrypton biorxiv.org/content/10.110…
Excited to be at @ParaFrap Next Generation in Parasitology Workshop. Looking forward to interesting talks on very small but complex organisms. cc: @KowaEva @msmosi
Right next to the scientific data, the #EMBLInfectionBiology conference is also centred on discussion and networking opportunities. 💬 Don't miss this opportunity! Submit your abstract by 25 September: embl.org/about/info/cou…
⚡ Deadline extension alert ⚡ Did you miss your chance to submit your abstract for #EMBLInfectionBiology? Then you're in luck: you now have time until 25 Sept! Present your work at this virtual conference and connect with the leading institutions in infection biology🧫 Submit…
We're excited to announce the publication of our latest study on the identification of a novel tRNA modification, 2-aminovaleramididine (ava2C), and its molecular basis on decoding. Congratulations and thanks to our wonderful collaborators! rdcu.be/dUr0l
Job alert-we are looking for a creative PhD student to join our team for an innovative CryoET and CryoEM research project on plant cell walls and membrane complexes. If you are interested send us an email!
🚨Just a reminder to download data you need from @veupathdb before next Saturday, the 14th of September 2024! 🚨
It appears #NIAID will shutter the genome data base we all use daily. This strikes me as a significant mistake that may well endanger much of our global progress. @BSPparasitology @AS_Para @ASTMH @TrendsParasitol @AmSocParasit @parasitesrule @PiParasitology
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