Cristina Paulino
@CPaulino_Full Prof @uniHeidelberg 🇩🇪, before 🇳🇱🇨🇭, from🇵🇹| Passion for #MembraneProteins, #cryoEM, #StructuralBiology, #Biochemistry. Mentor & Mother | she/her
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🥳big news🥳: 🇳🇱🔜🇩🇪The Paulino lab will be moving soon. I have been recruited as full professor to join the biochemistry centre (BZH) at the Heidelberg University and strengthen the HDcryoNet #cryoEM platform. bzh.db-engine.de/content/4377/s…
Just reviewed nominations for a prestigious chemistry award and < 5% nominees were women?!? 😳 Mentors - there are excellent women in chemistry, so PLEASE nominate them! Of course they shouldn't win just for showing up, but they'll never get to swim unless they're in the pool!🏄♀️
So she was first author on his key paper - in fact she's on most of his key papers, yet she didn't get the Nobel Prize, in spite of the fact they could have given 3 awards, not just 2. Explain to me how STEM is not institutionally sexist.
Congratulations to our 2024 medicine laureate Victor Ambros ✨ This morning he celebrated the news of his prize with his colleague and wife Rosalind Lee, who was also the first author on the 1993 'Cell' paper cited by the Nobel Committee. #NobelPrize
Dear cryo-EM women scientists, We want to honor you and your contributions at BPS 2025. This year, the Cryo-EM subgroup will honor a mid/senior-career woman scientist as the inaugural June Almeida awardee. June Almeida is the virologist who first discovered the coronavirus in…
Mark your calendars for the BPS CryoEM Subgroup Symposium, on Subgroup Saturday at @BiophysicalSoc Annual Meeting 2025! Also, we have a new award, the Almeida Award, for a mid/senior level woman who has made outstanding contributions to #cryoem. See you there!
2024 Murnau Structural Biology Meeting @GBM_eV kickoff by @CPaulino_ & Janosch Hennig! Three amazing days of structural bio and what makes the molecules of life move ahead! #4DStructuralBiology With a talk by our own Yasmine on TRPV4 on Friday! 😍 @microverse_exc @sfb1507
Some thoughts on the current state of single particle cryo-EM map/model validation. (TLDR: preferred orientation remains a big problem, ❤️ Q-scores. There's been progress, but there's still more to do. ) authors.elsevier.com/sd/article/S09…
🚀 Excited to share our preprint: CryoBench 🧊🪑: Diverse & Challenging Datasets for the Heterogeneity Problem in Cryo-EM! 🌐cryobench.cs.princeton.edu 🙌 Huge thanks to my amazing co-authors, collaborators, & advisor @zhongingalong! 🎉 #cryoEM #MachineLearning 🧵 Details below!
Cryo-EM heterogeneity analysis needs benchmarks and validation tools. We're very happy to share CryoBench 🧊🪑: cryobench.cs.princeton.edu lead by the amazing EZ team @MinkyuJeon19791 @ZhongingAlong with FI @miroastore geoff woollard @sonyahans
🚀 Excited to share our preprint: CryoBench 🧊🪑: Diverse & Challenging Datasets for the Heterogeneity Problem in Cryo-EM! 🌐cryobench.cs.princeton.edu 🙌 Huge thanks to my amazing co-authors, collaborators, & advisor @zhongingalong! 🎉 #cryoEM #MachineLearning 🧵 Details below!
Two open fully funded Postdoc positions in my lab in #cryoEM & #cryoET. See description below 👇Please share and spread the word. For all those interested in joining my group and work on exciting and collaborative projects please apply! drive.google.com/file/d/1Qs4roS…
🌟Exciting news!🌟 I’m thrilled to share our latest preprint, which marks a special milestone. This manuscript, authored by my brilliant PhD student @ciara_pugh is her first scientific paper with my group and presents the first high-resolution cryo-EM structure from my group!
Check out the preprint here: biorxiv.org/content/10.110… ❄️🔬 #CryoEM #MembraneProteins #NativeNanodiscs #AutzenGroup
Being a woman is kind of like being a cyclist in a city where all the cars represent men. You're supposed to be able to share the road equally with cars, but that's not how it works. The roads are built for cars and you spend a great deal of physical and mental energy being…
Researchers including @amborowska @CPaulino_ @MembraneEnzymo1 untangle the structural basis of the exchange mechanism of Na+ -dependent obligatory amino acid exchanger ASCT2. nature.com/articles/s4146…
As summer unfolds, remember to take a well-deserved break! Balancing academia & family is tough, so prioritize self-care, set boundaries, and explore new experiences. Disconnect from social media & focus on what matters. Here’s to a restful and memorable summer! @Momademia #STEMM
If this would not already be creepy enough, look at some of the answers. 🤮🤬
After giving a talk at a conference recently, I received an email from an unfamiliar senior professor in the audience remarking that my “look has extremely improved over the years” from “nerdy lab mouse” to “a touch of upper class.” 1/4
Could not be more proud to share my first PhD paper with you! Find out what makes an amino acid transporter ASCT2 function as an exchanger: rdcu.be/dPTze
It took some time, but Anna’s @amborowska beautiful work on the exchange mechanism of ASCT2 is now out. Together with twitterless Gabriella and @CPaulino @alisa_garaeva @rheinbergerj @CG_Martini nature.com/articles/s4146…
🚨 New Preprint from Grotjahn Lab🚨 We show that ribosomes oriented for import on mitochondria cluster, make multiple contacts with, and induce local ultrastructural changes to mitochondrial membranes at import sites @Atty_chang @benjaminbarad @hamid13r @ZidLab
Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import biorxiv.org/cgi/content/sh… #bioRxiv
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