HuaChen_BIG's profile picture. Population Geneticist, Principal Investigator; Beijing Institute of Genomics, CAS; China National Center for Bioinformation

Hua Chen

@HuaChen_BIG

Population Geneticist, Principal Investigator; Beijing Institute of Genomics, CAS; China National Center for Bioinformation

Joined March 2020
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A method for STR genotyping from NGS data. STRsensor: a computationally efficient method for STR allele-typing from massively parallel sequencing data academic.oup.com/bib/article/26…


Another methodology paper form the Chen Lab: SMART: STR Mixture Analysis and Resolution Tools - Forensic Science International: Genetics fsigenetics.com/article/S1872-…


A new paper from the Chen Lab: 3D Head Pose Estimation via Normal Maps: A Generalized Solution for Depth Image, Point Cloud, and Mesh - Wu - Advanced Intelligent Systems onlinelibrary.wiley.com/doi/10.1002/ai…


Hua Chen Reposted

We are celebrating the 50th anniversary this weekend in Tempe—thank you Science for the great article about this important milestone in human origins history!

Fifty years ago, paleoanthropologists unearthed the 3.2-million-year-old skeleton known as Lucy and transformed our views of humanity’s origins. Today, Lucy faces competition for the role of our direct ancestor but remains the best candidate. Learn more: scim.ag/6tI

ScienceMagazine's tweet image. Fifty years ago, paleoanthropologists unearthed the 3.2-million-year-old skeleton known as Lucy and transformed our views of humanity’s origins.

Today, Lucy faces competition for the role of our direct ancestor but remains the best candidate. Learn more: scim.ag/6tI


Hua Chen Reposted

OUT NOW ✨Longitudinal dynamics of farmer and livestock nasal and faecal microbiomes and resistomes nature.com/articles/s4156…


Hua Chen Reposted

New in Science: A vocal brain region is identified in bats and leveraged in comparative genomic analyses to reveal the evolution of mammalian vocal behavior. The results implicate networks of genes related to human autism. Learn more: scim.ag/6sw #Zoonomia

ScienceMagazine's tweet image. New in Science: A vocal brain region is identified in bats and leveraged in comparative genomic analyses to reveal the evolution of mammalian vocal behavior. The results implicate networks of genes related to human autism.

Learn more: scim.ag/6sw #Zoonomia

Hua Chen Reposted

Pleiotropy, epistasis and the genetic architecture of quantitative traits go.nature.com/3VK75YZ #Review by Trudy Mackay and Robert Anholt @ClemsonScience @ClemsonCHG


Hua Chen Reposted

A burst of evolutionary innovation occurred with the origin of snakes, a new Science study finds. The results highlight that many of the most spectacular changes in life histories involved macroevolutionary “singularities.” Learn more: scim.ag/62s

ScienceMagazine's tweet image. A burst of evolutionary innovation occurred with the origin of snakes, a new Science study finds. The results highlight that many of the most spectacular changes in life histories involved macroevolutionary “singularities.”

Learn more: scim.ag/62s

Hua Chen Reposted

Nature research paper: On the genetic basis of tail-loss evolution in humans and apes go.nature.com/3uQyFJ0


Hua Chen Reposted

Global and regional temperature change over the past 4.5 million years | Science science.org/doi/10.1126/sc…


Hua Chen Reposted

Awesome to see AllOfUs has sequenced ~250k people with detailed phenotype data! Will be great to have alternatives/complements to the UK Biobank nature.com/articles/s4158…

joe_pickrell's tweet image. Awesome to see AllOfUs has sequenced ~250k people with detailed phenotype data! Will be great to have alternatives/complements to the UK Biobank nature.com/articles/s4158…

Hua Chen Reposted

Ancient #retroviruses may be to thank for the evolution of vertebrate #myelin tissue—and, by extension, our large, complex brains. Read more in @CellCellPress: cell.com/cell/fulltext/… @altos_labs Tanay Ghosh, Robin J.M. Franklin

CellPressNews's tweet image. Ancient #retroviruses may be to thank for the evolution of vertebrate #myelin tissue—and, by extension, our large, complex brains.

Read more in @CellCellPress:
cell.com/cell/fulltext/…

@altos_labs Tanay Ghosh, Robin J.M. Franklin

Hua Chen Reposted

By mapping the meanings of the words used to communicate emotions across more than one-third of the planet’s spoken languages, a study in Science found that there is significant variation in how emotions are expressed across cultures. #ScienceMagArchives scim.ag/5Uo

ScienceMagazine's tweet image. By mapping the meanings of the words used to communicate emotions across more than one-third of the planet’s spoken languages, a study in Science found that there is significant variation in how emotions are expressed across cultures. #ScienceMagArchives scim.ag/5Uo

Hua Chen Reposted

In honor of #WorldAnthropologyDay, learn more about how the spread of agriculture didn’t just change our diets—it altered our jaws as well, making it easy to pronounce "f"s and "v"s and opening a whole new world of words. scim.ag/5SZ @NewsfromScience


Hua Chen Reposted

Dengue is spreading in Europe: how worried should we be? go.nature.com/47aXNaY


Hua Chen Reposted

An article published in @GenomeBiology presents CEGA: a method for detecting natural selection using both within-species genomic polymorphism and between-species divergence. genomebiology.biomedcentral.com/articles/10.11…


A new method for comparative population genomics from the Chen Lab: CEGA: a method for inferring natural selection by comparative population genomic analysis across species. genomebiology.biomedcentral.com/articles/10.11…


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