Keun Hong Son🇰🇷
@new__hongEvolutionary Cancer Biologist 👨🔬👨💻 | PhD cand. @je_yoel Lab, @SeoulNatlUni | Cancer susceptibility & resistance🧬, Multi-omics💻, Animal genomes🐘🐕
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Exciting news! Our lab’s latest paper in @ScienceAdvances on mapping the dog epigenome is out 🐶🧬! Close collaboration with my co-first authors @PrecursorCell + @MethylAReum! 🧵 👇(1/17) #ScienceResearch #ScienceAdvancesResearch #Epigenome science.org/doi/10.1126/sc…
A gentle introduction to pangenomics academic.oup.com/bib/article/25…
Earthworms have scrambled genomes?!?!?! Check out this article in @ScienceMagazine featuring @darwintreelife discussing how chaotic rearrangements of chromosomes helped leeches swim into fresh water and other worms wriggle onto land bit.ly/3ARZLSL
🔥 AI Scientist: LLM models handle it all—ideas, experiments, data, papers, peer review—for $15/paper! Time leverage is key to success. Personal AI world could revolutionize research, quant investing, and business with minimal staff. Fascinating times. 🥹 @SakanaAILabs #AI
A fire in our lab turned a normal night into a crisis I’ll never forget. In my recent blog, I share the harrowing experience and the immediate response as we faced the disaster. Read more here: keun-hong.github.io/lablife/lab-fi…
I recently shared my experience in revamping our lab’s outdated website, setting up a new center’s site, and even creating my own personal webpage. Big thanks to @WordPress for making it all possible! Check out my journey here: keun-hong.github.io/lablife/websit…
I set up a Lab and personal cloud using NAS to manage data efficiently and learned a lot in the process. If you have any tips or better methods, I'd love to hear them! Grateful to @Synology for making the setup smooth and easy. keun-hong.github.io/lablife/nas/
In my latest blog, I dive into genome mappability—a key metric in genomics, especially for short-read sequencing. I also break down how to calculate it using the Umap tool developed by the @michaelhoffman Lab. #Genomics #Bioinformatics keun-hong.github.io/bioinformatics…
SonicParanoid2: fast, accurate, and comprehensive orthology inference with machine learning and language models genomebiology.biomedcentral.com/articles/10.11…
In Science, researchers engineered #Cancer cells with and without specific chromosome abnormalities, showing how tumors rely on them for survival and clarifying the biological role of aneuploidy. Check out the study on #WorldCancerResearchDay: scim.ag/4cZ
Interested in #phylogenetics using whole #genome/#transcriptome/#proteome data? @C__Hahn and I are very happy to share phylociraptor with you: It facilitates explorative and reproducible phylogenomic analyses of thousands of genes and genomes. Preprint: tinyurl.com/yc4f7v6d
Just out @ScienceMagazine #AlphaMissense—building on #AlphaFold—based on unsupervised learning #AI, predicts impact of all 71 million human missense variants for disease-causing potential, across entire human proteome; open-source👍 science.org/doi/10.1126/sc… @jun90cheng @Avsecz
A new study tested 23 avian species, including the blue jay, and discovered that species with greater vocal learning abilities have greater problem-solving abilities and bigger brains. Learn more this week in Science: scim.ag/464
The latest on human total body cell count and cell size derived from >1,500 sources @PNASNews Men ~36 trillion cells Women ~28 trillion cells an inverse relationship between cell size and count pnas.org/doi/10.1073/pn…
Nature research paper: The complete sequence of a human Y chromosome go.nature.com/3KPVjpC
Congratulations to everyone involved in this great paper in @NatureBiotech about Monopogen, a computational tool that detects single-nucleotide variants, to help uncover genetic drivers of cell processes.
Excited to share Monopogen that performs SNV calling from single-cell DNA/RNA/ATAC-seq data, to enable cellular population genetics. nature.com/articles/s4158…. Thanks Rui Chen, @nicholas_navin, @shyam_lab, Li Ding, @czi @cziscience, #HTAN, @NatureBiotech collaborators/friends.
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