@DouglasHoltMD Profile picture

Douglas Holt

@DouglasHoltMD

Radiation Oncologist - Idaho Cancer Center | Improving Patient Experience | Virtual Reality for Patient Ed | https://t.co/vb8eaOgC3o - Video Distraction

Joined May 2019
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Pinned

kdvr.com/news/local/new… RadFlix - co-developed with @BWMolinero, thanks for support of @SarahMilgrom & @BK_radiation for this project, as our mission is to improve the patient experience in a meaningful way. Excited for the publicity from @uchealth @kevinltorres @PRJessDenver


Douglas Holt Reposted

Congrats to all authors for the new ESTRO-EANO guideline on target delineation and radiotherapy for IDHmutant WHO CNS grade 2 and 3 diffuse glioma - Radiotherapy and Oncology @EANOassociation @ESTRO_RT @MaxNiyazi thegreenjournal.com/article/S0167-…


Douglas Holt Reposted

#WorldArthritisDay @RadioterapiaHM experience: 260 patients with OSTEOARTHRITIS underwent low-dose radiotherapy #LDRT After 🔟 years of FU: - 2/3 of patients remain pain and functionalitiy benefit 🏃‍♂️ - ⁠40% need less 💊 - ⁠NO TOXICITY ☢️ #LDRT is safe and effective for OA!

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Douglas Holt Reposted

❗️ Phase 3 RCT oligomet NSCLC EGFRm -> TKI +/- 60 Gy PFS HR 0.57; P = .004 OS HR 0.62; P = .029 mOS 26.2 vs 34.4 mos More data supporting aggressive RT in oligomet disease! ascopubs.org/doi/10.1200/JC…


Douglas Holt Reposted

🚨 First Modern American Study on LDRT for Osteoarthritis At @ASTRO_org , we presented the first modern American study to explore the effectiveness of low-dose radiotherapy (LDRT) in alleviating pain for osteoarthritis patients. ❇ Conducted at the Leonard C. Ferguson Cancer…

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Douglas Holt Reposted

Another great oral presentation at #ARS2024. Our @MDAndersonNews #RadOnc PGY4 resident @MichaelRooney67 gave a compelling talk on the role of RT dose to the anterior vaginal wall as a predictor of sexual pain after chemoRT for Anal cancer. Take home message- keep the V35 < 60%!!

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Douglas Holt Reposted

As always, I'll take this chance hit the replay button on my love of Xofigo. It took less than a year to update my rural hospital's NRC license and start a program from scratch - and obviously, most of that was just waiting for paperwork (lol).

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Calling all #RLT fans. Amazing data presented by @Silke_Gillessen bringing back an oldie but a goodie. Large phase 3 PEACE3 results showing OS benefit with #radium223 without significant increase in toxicity in the frontline mCRPC setting.

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Douglas Holt Reposted

Dear colleagues, please help me remember whose slide this is so I can give appropriate attribution in future talks. It's a contemporary masterpiece. #radonc @IyengarPuneeth @Jbauml @drdavidpalma @fifimcdrmh @CJTsaiMDPhD

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Douglas Holt Reposted

🚨 New Insights into Patterns of Locoregional Recurrence in #PancreaticCancer after TNT & Their Impact on Neoadjuvant RT Volumes 🚨 pubmed.ncbi.nlm.nih.gov/39182645/ #PancSM #Radonc 🙌 @SaraBelPonMD n=1/8

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Douglas Holt Reposted

Case Report: Role of Boswellia Serrata in Management of CNS Radiation Necrosis After Radiosurgery for Brain Metastases 🔗 bit.ly/48mCy6n #RadOnc #RadOncEd #MedEd #CaseReport

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Douglas Holt Reposted

Hot off the press in @IJROBP: the ARREST phase I trial of SABR in poly-metastatic disease, led by @lhscradonc & @TimkWin Average number of lesions = 16 Dose safely escalated to 30 Gy in 5 fractions. sciencedirect.com/science/articl… The phase II/III RCT ARREST2 is underway!

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Douglas Holt Reposted

Practical Considerations for the Treatment of an Adrenal Metastasis With Stereotactic Body Radiation Therapy - Practical Radiation Oncology practicalradonc.org/article/S1879-…


Douglas Holt Reposted

🚨Need for Formal Education in Treating Benign Conditions with Radiotherapy🚨 The field of radiation oncology is rapidly evolving, with a growing demand for radiotherapy to treat benign diseases. However, many radiation oncologists lack comprehensive training in this area.…

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Douglas Holt Reposted

Improving symptom palliation in pancreas cancer critical. Great presentation by Dr. Chiorean. Wanted to add celiac SBRT as option – multiple studies showing high efficacy rates w 25 Gy x 1 (Yaacov Lawrence) or 8 Gy x 3 (PAINPANC trial) Also now in 2024 NCCN guidelines! #ASCO24

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Douglas Holt Reposted

We really need to lobby hard to get SBRT into NCCN guides as Cat 1 in all the areas where we have RCT’s (which is more and more)

🚨 TACE + TKIs +/- SBRT OS (17.93 vs. 9.61 months, HR=1.869 [95%CI, 1.059-3.266], P=0.017) Survival benefit with SBRT #asco2024

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Douglas Holt Reposted

Really important study highlighting the AEs from SpaceOAR, including 5 mortalities Our editorial that accompanied the @JackMillot_ publication in @urogoldjournal goldjournal.net/article/S0090-… #AUA24 @urotoday @Barrigel_spacer @teleflex

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Douglas Holt Reposted

1/ Next up NARLA2 #LUNGCANCER trial at #ESTRO24🔥🔥🔥 PET guided dose escalation phase III (because 60-66 Gy is not high enough for many tunors‼️)

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Douglas Holt Reposted

Improved locoregional control with PET-guided inhomogeneous dose escalation in locally advanced NSCLC! 😍 The NARLAL2 trial randomised 350 pt to 66Gy/33# or up to ~94Gy boost. Locoregional control: 50% vs 60% at 24m. No increased toxicity! #ESTRO24 #radonc #NSCLC

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Douglas Holt Reposted

Just published in @TheLancet Oncology: Delphi consensus on stereotactic ablative radiotherapy for oligometastatic and oligoprogressive renal cell carcinoma — an ESTRO study endorsed by EAU. 👉 Read the summary: bit.ly/3Wtqb5Y @Uroweb

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Douglas Holt Reposted

Design and main results: 🚩MDT vs ENRT, both arms 6mo of ADT 🚩Higher GU2+ tox in ENRT arm, but mainly due to more prostate bed RT in this arm 🚩Omitting PB RT results in higher rate of local failures 🚩Locoregional control superior with ENRT: 90% control @ 3yr. 🏴MFS not mature

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Douglas Holt Reposted

#ESTRO24 @piet_ost presenting outcomes of STORM randomized Ph II of MDT v ENRT for oligorecurrent prostate cancer #pcsm ✅ ENRT ⬆️BRFS, LRFS MDT a/w 8-fold ⬆️ nodal recurrence 3➡️25% Omitting PB ⬆️ local recurrences 3-fold (5➡️14%), but also increases GU2+ toxicity

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