Manika Singh
@singh_msmanikaComputational biologist
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A multicentre study to evaluate the diagnostic performance of a novel CAD software, DecXpert, for radiological diagnosis of tuberculosis in the northern Indian population pubmed.ncbi.nlm.nih.gov/39237689/?utm_…
pretty cool result: using a new mathematical model, scientists estimate that the ancestral human population shrunk to just 1280 individuals about 900,000 years ago. We almost went extinct, but... science.org/doi/10.1126/sc…
ICYMI some really fantastic research from an all star cast 👇 Handles: @sritchie73 @aidanbutty @Di_Angelantonio @HasangaDM @GadAbraham1 @xilin_jiang @cfoguet @markmccarthyoxf @anubha_M_Oxf @iamslambert @AllofUsCEO @jdnashville @JohnNDanesh and others I'm surely missing!
📣📣📣 Our latest PGS work, led by @sritchie73: Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk score medrxiv.org/content/10.110… -New metaPRS for T2D -Transferable b/n ancestries -Added value to QDiabetes -Risk strat for dysglycemia tests
Excited to share our latest preprint which could be a game-changer for public health in regions struggling with TB. Don’t miss out on the potential of AI to transform healthcare! researchsquare.com/article/rs-437… #Tuberculosis #AI #HealthcareInnovation
Ploidy inference from single-cell data: application to human and mouse cell atlases. New article published in Genetics doi.org/10.1093/geneti… together with a new release of the package scPloidy CRAN.R-project.org/package=scPloi…
Calling all early career researchers interested in polygenic scores, multi-omics and multi-morbidity! @iamslambert and I are recruiting a Postdoc in Biomedical Data Science, based at the gorgeous @HLRI_Cambridge @CAMBRIDGE_CEU @CamBioCampus jobs.cam.ac.uk/job/45465/
Check out our latest review on polygenic (risk) scores, including the FAIR (Findable, Accessible, Interoperable, and Reusable) use to maximise its clinical utility!
Just out at @GenomeMedicine: our review on recent advances in polygenic scores: translation, equitability, methods and FAIR tools genomemedicine.biomedcentral.com/articles/10.11… Well done to the team @RXiang5 @iamslambert Martin Kelemen @IamYuXu @DrP_stuff @HarrisWiseman!
The Harvard Medical School Immunology Webinar Series kicks off the Fall program this Wed Sep 2nd, 4pm EST with Dr Joanne Flynn. Check out the full schedule: dms.hms.harvard.edu/immunology/eve… Zoom link: harvard.zoom.us/j/94953340992?… Passcode: 840345 Open to all- please retweet!
One PhD scholarship in computational metagenomics is available at @BioSci_UniMelb @MelbIntGen in co-supervision with @heroenv, @hologenomics and myself. Apply within before July 24! 👇 lecao-lab.science.unimelb.edu.au/2020/06/30/emr…
[Job opening] AstraZeneca is looking for a PhD-level biostatistician working in proteomics. Apply at astrazeneca.wd3.myworkdayjobs.com/Careers/job/US…
If you are a recent Australian bioinformatics PhD graduate check this out...
Announcing: The @abacbs PhD Thesis Award! Applications are open for outstanding PhD theses awarded in the past two years by Australian students. Applications close April 30. Check it out and nominate yourselves, your colleagues or you students abacbs.org/awards
Florence Nightingale made this plot... by hand... a mere ~50 years after the word statistics was first used, ever... Insane. She is such a hero.
The Department of Genome Sciences at the University of Washington is looking to hire an Assistant Professor in the field of proteomics. #proteomics #MassSpec apply.interfolio.com/54733
No funny Friday, but an inspirational one. Here's to Dr. Rosalind Franklin. bit.ly/2aiBtSv
Plans for a second edition of my textbook, Statistical Rethinking elevanth.org/blog/2018/07/1…
Here is the video for my keynote from #useR2018 on teaching R to new users. youtu.be/5033jBHFiHE
Selection did act against Neanderthal alleles, & shaped patterns of Neanderthal ancestry along H. genome. But @fleventy5 et al argue that it is not the primary cause of the apparent changes in Neanderthal admixture through time biorxiv.org/content/early/…
While we know lots about the genetic variation in the euchromatic genome, we know very little about what's going on in the highly repetitive heterochromatin.....until now!! A big surprise - some of us may have Neanderthal centromeres!! biorxiv.org/content/early/…
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