@shivani0730 Profile picture

Shivani Sharma

@shivani0730

PhD@UNESCO-RCB

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Shivani Sharma Reposted

Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8


Shivani Sharma Reposted

Remember, I said 5ml bacterial cultures for the isolation of ribosomes. Well, I was wrong you need 1ml culture at 0.3 -0.5 absorbance at OD600nm for this "Ribosome and RNA mini prep". Pretty good for CryoEM or any biochemical tests. Here in these figures are ribosomes purified in…

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Shivani Sharma Reposted

Collaborative work of @slavicaPD, @Hashemyaser4, Jovanovic Lab and @DjuranovicLab - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact…


Shivani Sharma Reposted

Excited to share that our @smcvdb providing detailed toxicity data on small molecules, is now published in DATABASE - The Journal of Biological Databases and Curation! Check it out here: academic.oup.com/database/artic… #Bioinformatics #DrugDiscovery #Toxicology #Database @unescorcb


Shivani Sharma Reposted

Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea biorxiv.org/cgi/content/sh… #biorxiv_cellbio


Shivani Sharma Reposted

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

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Shivani Sharma Reposted

Our new paper is finally out! We discovered that the human tumor suppressor protein Pdcd4 binds to the #mRNA entry channel in the 40S ribosomal subunit, where it blocks the eIF4F-independent role of eIF4A. #ribosome #CryoEM @umichrna @UMLifeSciences nature.com/articles/s4146…


Shivani Sharma Reposted

One of the talented students @shivani0730 in our lab. presented poster at Translation Control meeting at CSHL. Pleased to see my mentor Dr. Agrawal visited the poster. @unescorcb @DBTIndia

Amazing few days at @CSHL for Translation Control 2024 meeting. Presented poster on Ribosome structure from Entamoeba.Thanks to my mentor @ prem_s-kaushal. Many thanks to @IndiaDST for travel grant and @unescorcb

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Amazing few days at @CSHL for Translation Control 2024 meeting. Presented poster on Ribosome structure from Entamoeba.Thanks to my mentor @ prem_s-kaushal. Many thanks to @IndiaDST for travel grant and @unescorcb

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Shivani Sharma Reposted

Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  biorxiv.org/content/10.110…


Shivani Sharma Reposted

Explored my creative side with this artwork that I submitted for the @IndiaBioscience Science art competition! The composition celebrates the women in STEM who have broken the stereotypes and are contributing immensely towards scientific progression.

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Shivani Sharma Reposted

bioRxiv: Molecular basis of mRNA delivery to the bacterial ribosome dlvr.it/T4KX4p


Shivani Sharma Reposted

Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells! biorxiv.org/cgi/content/sh…

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Shivani Sharma Reposted

This is what great writing looks like:

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Shivani Sharma Reposted

Let's gooooooo!!!

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Shivani Sharma Reposted

Checkout latest work from the Agrawal Lab on mycobacterial HflX biorxiv.org/content/10.110… @cryoEM_Papers


Shivani Sharma Reposted

My cancellable hot-take during 3DEM GRC season: CryoSPARC non-uniform refinement is an overfitting machine and should not be used.


Shivani Sharma Reposted

Similarly, faculties staying on campus are also charged Rs. 13.65/unit, for domestic household consumption. Which is much higher compared to the electricity rate in Faridabad. I do not understand the rationale behind this & why we should pay this much. @unescorcb @DBTIndia

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Electricity unit rate at Rs. 13.65 and a per month bill for a small sharing room at Rs 5k per person. Cheery on the cake is irregular fellowship. This is nowhere feasible for scholars. @unescorcb @DBTIndia @sushant16m8 @LaviRastogi9 @Kriti_ahuja9090 @ROHANBA71171023



Shivani Sharma Reposted

@DBTIndia @unescorcb is charging its scholars 13.65 rupees per unit i.e. commercial rate. Is this fair to charge commercial rate electricity charges to students ? We are already paying our HRA that too for a sharing room. This is my electricity bill for July, per person.

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Shivani Sharma Reposted

Ribosome meeting 2024 (Dec 2 - 4) at The institute of Medical Science, The University of Tokyo, organized by Prof Inada. @inada_lab . inada-lab.ims.u-tokyo.ac.jp/%E3%82%BB%E3%8…

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