@nvhilten Profile picture

Niek van Hilten

@nvhilten

Postdoc at Michael Grabe's lab at University of California, San Francisco.

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Pinned

📢Yay! The paper accompanying our web server PMIpred is now published in Bioinformatics. Let me tell you the story of how this work came about and how it can be useful for you. 🧵1/n academic.oup.com/bioinformatics…


Stoked to be in beautiful Tahoe this week for some amazing biophysics (and trail exploration). @BiophysicalSoc #BPStahoe

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Niek van Hilten Reposted

Generative AI methods for generating structure (or worse, generating dynamics) are doomed if they do not incorporate physical (and dynamical) priors coming from intuition, experience, theory, experiments and simulations. How to mix priors from different sources of knowledge, how…

New Practical Cheminformatics Post, "Generative Molecular Design Isn't As Easy As People Make It Look", practicalcheminformatics.blogspot.com/2024/05/genera…

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Bike to work y'all!

Are you thinking about biking to work? It’s more than just a thought; it’s a step toward a healthier, greener commute. For #BiketoWherever Day John Hamiga from UCSF Bikes! shared a guide to kickstart your biking journey. tiny.ucsf.edu/pMd6dt



Niek van Hilten Reposted

Hello, my absolutely lovely membrane peeps! Would you maybe, pretty-please, let me proudly steer you to a MINI-REVIEW I recently wrote? It’s on asymmetric membranes in general, and differential stress in particular—subjects that I am massively interested in right now! 1/26

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Eager to try this out!

I am proud to present our work “GōMartini 3: From large conformational changes in proteins to environmental bias corrections”. Take a look in the @biorxivpreprint here: biorxiv.org/content/10.110…

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Niek van Hilten Reposted

Interesting work: Analyzing Lipid Membrane Defects via a Coarse-Grained to Triangulated Surface Map: The Role of Lipid Order and Local Curvature in Molecular Binding Poke @WPezeshkian pubs.acs.org/doi/10.1021/ac…


Niek van Hilten Reposted

Our New Issue is out 🎉 Check out our new papers, including: 🖋️ When Data Are Lacking: Physics-Based Inverse Design of Biopolymers Interacting with Complex, Fluid Phases #OpenAccess 🔓 go.acs.org/8u5

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How to design biomolecules when there is very little data to start from? Check out this perspective paper on physics-based design by my former colleague Jeroen Methorst at @LeidenScienceEN, now out in @JCIM_JCTC pubs.acs.org/doi/epdf/10.10…


Yes please

Best Gromacs feature discussed so far @WillPPK 👏

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