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Niklas Schmacke

@niklas_a_s

Shared PostDoc in Veit Hornung’s lab and Fabian Theis’ lab in Munich. Let‘s go.

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Fresh on bioRxiv: @sophiaMaedler and I developed ✨SPARCS✨, a technology for microscopy-based genome-wide genetic screens in human cells🔬🧬 biorxiv.org/content/10.110… This work was enabled by the amazing collaborative environment created by @hornung_lab and @labs_mann 🧵👇

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Niklas Schmacke Reposted

📢 Postdoc opening! 📢 @SorekLab and @hornung_lab are looking for outstanding candidates for a position at the intersection of computational biology & innate immunity. Dive into impactful research across two dynamic fields. Interested? Let’s connect! 👇 genzentrum.uni-muenchen.de/career/postdoc…


Via Deep Visual Proteomics (microscopy 🤝 mass-spec-based proteomics), we - identified disease-related cellular phenotypes - in liver cells - in an unbiased manner using deep learning Glad I could contribute to the newest story from Florian Rosenberger @metaboflo at @labs_mann

AATD affects thousands, causing liver & lung disease via protein aggregation. Our new preprint used #DeepVisualProteomics to study liver cells and reveals key AATD insights with clinical implications . Video and tweetorial @metaboflo #Alpha1Awareness bit.ly/4hzl64o



Niklas Schmacke Reposted

Fancy a postdoc in Munich? For a collaborative project between @SorekLab and @hornung_lab on antiviral innate immunity, we are looking for exceptional candidates with skills in immunology / biochemistry / computational biology. More details here: genzentrum.uni-muenchen.de/career/postdoc…


If you’re looking to do research in single cell atlassing: Working with Malte and his group is a fantastic opportunity.

Are you interested in sc-spatial multiomics data, motivated by improving patient outcomes in lung cancer, and keen to join a young and growing lab taking single-cell atlassing to clinical applications? Please apply :). We're looking for Postdocs! jobs.helmholtz-muenchen.de/jobposting/43b…

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Niklas Schmacke Reposted

Published today! Spatial proteomics reveals JAK/STAT as a target for Toxic Epidermal Necrolysis, an often fatal skin reaction to common medication. We validated our findings in pre-clinical models & successfully treated the first patients worldwide.🧵⬇️ nature.com/articles/s4158…


Niklas Schmacke Reposted

PhD ✅ Excited for what's up ahead 🚀 Many thanks to my colleagues, friends and family for all of the support throughout this journey🧸It wouldn't have been possible without you. Especially big shout-out to @labs_mann @niklas_a_s @v_hornung @BoehringerIngelheimFonds @IMPRS_ML

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Niklas Schmacke Reposted

Explore the research done at Moritz Gaidt’s lab with the Vienna BioCenter #PhD Program (@TrainingVbc)! ⏳ Deadline: October 15 (or apply in Spring). Don't miss your chance—apply now: training.vbc.ac.at/phd-program/ 📽️Watch Moritz Gaidt's 'Scientist Snapshot': youtube.com/watch?v=R7nwAW…

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Niklas Schmacke Reposted

We are searching for an Asst Professor in Immunology and Molecular Medicine @berkeleyMCB @UCBerkeley Any area of immunology, broadly defined. Deadline is Nov 1. Please help us spread the word and RT! Go Bears! aprecruit.berkeley.edu/JPF04513


Niklas Schmacke Reposted

Excited to present “scooby”, which models multi-omic profiles (scRNA-seq coverage & scATAC-seq insertions) directly from 500 kb DNA sequence at single-cell resolution. This was a fantastic collaboration co-led with @thisisjohahi biorxiv.org/content/10.110…

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Niklas Schmacke Reposted

Petr presenting @AlexandraBoegli’s exciting new NLRP6 story at #EMBOinflammasomes24. Keep your eyes out for this one - it’s got inflammasomes and pathogens and lots of cool cell biology!

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Opening remarks of #EMBOinflammasomes24 by @v_hornung We have it on good authority now: NLRP1 is on the rise, but NLRP3 is still the undisputed king of inflammasomes 👑

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I have been part of that team for my PhD, and am still wrapping up a few projects as a PostDoc now. Happy to chat if you‘re considering applying 🍻

📢 postdoc opportunity! We’re a team of innate immunity enthusiasts working at the exciting interface of immunology & biochemistry. If you’re passionate about how the immune system recognizes non-self, we’d love to hear from you! Interested? Apply here 👇 genzentrum.uni-muenchen.de/career/postdoc…



Niklas Schmacke Reposted

Loved presenting at #scverse24 today. So many interesting followup discussions already!

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Niklas Schmacke Reposted

Today is the day: Our application portal is now open! 📣 Contact your referees, get your documents ready, and submit your application by 13 October! ↪️ More info here: imprs-ml.mpg.de/5103/How-to-Ap… @MPI_Biochem @MPIforBI @LMU_Muenchen @TU_Muenchen


David is a great guy and a committed researcher. If you’re interested in AI in biology and can imagine working in beautiful Vienna, joining his lab is a tremendous opportunity🚀

We currently have openings for a PhD Student and a PostDoc, both focused on mechanistic ML methods that effectively use prior knowledge from molecular biology. Interested? More info here: ai4biomedicine.org/team/#open-pos…



Niklas Schmacke Reposted

We’ve just finalized the program for our EMBO Inflammasome Workshop. 🙌 Next to many amazing short talks, we have an incredible lineup of poster presentations featuring lots of unpublished work. Check out the full agenda on our website—there’s still time to register! 👇

Our official poster is out 🪧 EMBO workshop "The inflammasomes - 2024". September 24 - 27, 2024 | Planegg-Martinsried, Germany - 4 keynote lectures - 20 talks - 15 short talk slots - many networking opportunities - 🎡 & 🥨 & 🍻 Register here 👇 meetings.embo.org/event/24-infla…

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Niklas Schmacke Reposted

Attending Benzon Foundation meeting on AI for Clinical Mass Spec in beautiful Copenhagen this week? Come and chat to @_sabrinarichter and myself on latest deep learning work we are doing to model and analyse MS data @fabian_theis lab!

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Niklas Schmacke Reposted

📢Exciting news! Rotem Sorek @WeizmannScience joins us for a prolonged research stay🤗🤩 ➡️The winner of the Max Planck Humboldt Research Award 2023 will continue his investigations on key mechanisms of the bacterial and human immune system😃 @SorekLab @LMU_Muenchen

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Niklas Schmacke Reposted

I'm stoked to announce our new end-to-end framework for perturbation analysis! Our scverse advisory committee highlighted that a maintained and well-documented framework for perturbation analysis is missing. Pertpy is our attempt to satisfy this request biorxiv.org/content/10.110…

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