@nickpease32 Profile picture

Nick Pease

@nickpease32

Postdoc at Center for Systems Immunology at University of Pittsburgh

Joined August 2020
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Nick Pease Reposted

Excited to announce that our study on T cell antigen perception by long term signaling dynamics, led by the brilliant Matt Wither, is now published! pnas.org/doi/10.1073/pn… For a tweetorial, see: x.com/Kueh_Lab/statu…

Excited to announce our latest preprint, on antigen perception by T cells. This study was led by the brilliant, fearless Matt Wither, who is also defending his PhD this week! See tweetorial below: (1/n) biorxiv.org/content/10.110…



Nick Pease Reposted

Excited to announce our latest preprint, on antigen perception by T cells. This study was led by the brilliant, fearless Matt Wither, who is also defending his PhD this week! See tweetorial below: (1/n) biorxiv.org/content/10.110…


Nick Pease Reposted

Do you ever question prior decisions as you gain new information? Do you wonder if immune cells do too? Check out our @Kueh_Lab preprint about a flexible T cell decision-making strategy that enables robust and scalable control of immunological memory tinyurl.com/58mha28t (1/n)


Nick Pease Reposted

If you are interested in ways to modulate the immune system in antigen-specific manner, join us! joglekarimmunolab.org We have an awesome lab culture that emphasizes hard work, high quality science, positive and inclusive environment, and having fun!


Nick Pease Reposted

In our new deep antibody profiling paper in @CellReports, cell.com/cell-reports/f…, we find Abs targeting conserved non-canonical Ags & endemic coronaviruses associate with favorable outcomes in severe #COVID19. Shows importance of studying Ab profiles against Ags beyond Spike/RBD


Nick Pease Reposted

Join us today to learn about what T cells 'see' in immune response, how to identify their targets, and about the exciting research from our lab !!

dkNET & co-host HIRN present “T Cell #Antigen Discovery: Experimental And Computational Approaches” with Dr. Joglekar - Join us this morning 9-10 am PT @alokjoglekar @UPittEndo 👉 Topics: detection of #Tcells, antigenic landscape in #T1D, etc. 👉 Info: dknet.org/about/blog/2435

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This will be a huge loss (temporarily) for the @Kueh_Lab but we know @kathleenabadie will continue to do amazing work with the @IdoAmitLab! Very excited for you Kathleen and can't wait to see what creative project you come up with!

Congratulations to @kathleenabadie w/ the @Kueh_Lab on receiving a 2021 Fulbright Fellowship for her immunotherapy research! She’ll study w/ @IdoAmitLab in Israel. Also: Cheer on her pro cycling team at Nationals!🚴‍♀️@uwgenome @UWMedicine @uwengineering bioe.uw.edu/kathleen-abadi…



Nick Pease Reposted

@briscoejames and I wrote a review where we discuss how the comparison across species in biological contexts may help us decipher the timekeeping mechanisms in development & homeostasis. Hope you like it! #aboutime 🐭⌛️👤⏳ royalsocietypublishing.org/doi/10.1098/rs…

It's time's time! Our special issue addressing current questions to dynamics in biology is out. Thanks to all the contributors, the @royalsociety, and to my partner in crime @BertaVerd royalsocietypublishing.org/doi/10.1098/rs…



Nick Pease Reposted

Excited and honored to give my first talk as a grad student tomorrow at #cshlsysimm on my research in the @Kueh_Lab! We clarify mechanisms for CD8 T cell differentiation using live imaging and sci-fate-seq, in collaboration with @JShendure , @junyue_cao , and @VinetteY


Nick Pease Reposted

Single Molecule Genomics? Isn't single cell good enough? My attempt to explicit the concepts and share my excitement on how this may give a fresh view on the molecular mechanisms regulating transcription. Free link👇 authors.elsevier.com/a/1cxXzcQbI-uTB

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Nick Pease Reposted

My first ever paper tweet (not an April Fool’s Day joke 😉): Our COVID-19 paper is officially out in today’s issue of @CellCellPress (cell.com/cell/current): cell.com/cell/fulltext/…. Please check it out if you haven't seen the pre-proof.


Excited to share work done with Sam Nguyen and @Kueh_Lab providing evidence for a chromatin-based mechanism that finely tunes the timing of a developmental cell fate decision over many days and cell generations. cell.com/cell-reports/f…

Finally – it’s out!! Thrilled about our new paper, on a timed epigenetic switch controlling the T-cell fate decision. This study was co-led by the dynamic experiment/theory duo @nickApease and Sam Nguyen. (1/n) cell.com/cell-reports/f…



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