Milan Savani
@milan95MD-PhD candidate in the McBrayer lab @CRI_UTSW & @UTSWnews. @PennSAS & @Wharton grad. Views my own; RT ≠ endorsements. He/him.
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Collab🚨: CRI's McBrayer Lab contributed to a discovery published in @ScienceMagazine from @MangusoLab & Bardeesy Lab at @MGHCancerCenter that defines a new #cancer-causing mechanism associated with IDH1 mutations (the most commonly mutated metabolic gene across cancers). From…
New in @sciencemagazine! Our study reveals how mutant IDH1 inhibition activates tumor immunity by inducing dsDNA sensing. Read more: science.org/doi/10.1126/sc… #CancerResearch #Cholangiocarcinoma #IDH1 1/n
Our lab is hiring at all levels! We’ve got multiple cool projects looking at metabolism, placenta biology, chromatin regulation. Click here to read more: labs.utsouthwestern.edu/solmonson-lab And email me at Ashley.solmonson@utsouthwestern.edu if you are interested!
In the latest edition of @CellPressNews Trends in Cancer, the McBrayer lab at @CRI_UTSW reviews the emerging roles that nucleotides play in cancer metabolism. Learn more at sciencedirect.com/science/articl…
Excited to share our new review covering recent work on nucleotide metabolism in cancer! Free access link here: authors.elsevier.com/a/1h2%7E0_sivv…
The September issue of Cancer Cell is out! Read and spread the news: cell.com/cancer-cell/is…
Was great to have the chance to present our recent work from the McBrayer lab at #KSTumorMetabolism22 – thanks to the organizers, Sam, @RJDLab, our collaborators, and everyone at @CRI_UTSW! Check out the paper at doi.org/10.1016/j.ccel…
Online Now: De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma dlvr.it/SWsG4m
New research in @Cancer_Cell from the McBrayer lab identified the de novo pyrimidine nucleotide synthesis pathway as a targetable vulnerability in IDH1 mutant brain tumors. These findings establish the basis of a clinical trial expected to begin next year. cri.utsw.edu/researchers-id…
Scientists in the McBrayer lab developed a new method to create surgically-explanted organoids from patients with #BrainCancer, resolving a long-standing roadblock to studying lower-grade brain tumors in the lab. Learn about the study in Neuro-Oncology. ⤵️ bit.ly/3lBdNNN
Are you a scientifically-minded professional with flow cytometry experience who enjoys helping others make discoveries? @SJMorrison_ lab & @CRI_UTSW are hiring a research specialist to manage the flow cytometry core. Learn more below. #ScienceCareers jobs.utsouthwestern.edu/job/15618445/s…
Congratulations to McBrayer lab postdoc Yi Xiao (@yixiaobio) on receiving the prestigious @HFSP’s long-term fellowship! This grant will help him investigate the mechanisms of metabolic-epigenetic crosstalk that promote brain tumor formation. cri.utsw.edu/mcbrayer-lab-m…
new preprint just dropped 👀 a thread:
Cloaked in mystery for decades, the RNA capping mechanism of coronavirus (SARS-CoV-2) is unveiled. Congrats to @UTSWNews colleague V.Tagliabracci & lead authors @ginajpark & A.Osinski for this amazing discovery. @HHMINEWS biorxiv.org/content/10.110…
Meet Alex Sternisha, an M.D./Ph.D. student in the McBrayer lab! He studies how small molecules that are produced and consumed by living cells can control the fate of individual cells by shaping genomic DNA structure. Learn more about his work & #LifeAtCRI cri.utsw.edu/life-at-the-in…
Don’t miss this virtual info session next week about @UTSWmstp and hear from CRI member Alex Sternisha, an MSTP student in the McBrayer lab about his experience.
Interested in MD/Ph.D. programs? Don't miss the @UTSWNews Medical Scientist Training Program (MSTP) Virtual Info Session next week, 9/22 at 6 pm CT! Chat with our Program Director and current students about the program and admissions process! Register now: bit.ly/3yTVhVf
Amplifying the Noise: Oncometabolites Mask an Epigenetic Signal of DNA Damage dlvr.it/RdJMmp
Excited to share this Spotlight in Molecular Cell from my current lab rotation, highlighting exciting work on a link between cancers with mutations in metabolic genes and DNA repair from @parkersulkowski and colleagues authors.elsevier.com/a/1bX5k3vVUPDf…
Congrats to @BrittMStew in the lab for receiving an @AmerSocVirol student travel award for #ASV2020. While the conference is canceled, it is great to have Brittany’s hard work and cool story recognized!
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