@kath_shah Profile picture

Kathleen Shah

@kath_shah

Long-time mucosal biology junkie venturing out into the unknown (she/her) 🇨🇦🇵🇭🇧🇩🌏

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Kathleen Shah Reposted

Arp2/3 iso-complexes strike again & Way lab does Immunology! Outstanding work from @vasconcell57624 @ShainaHuang_ @NaokoKogata @TheCrick explain why mutations in the ARPC5 subunit of the Arp2/3 complex are bad for your health biorxiv.org/content/10.110…


Kathleen Shah Reposted

Early Christmas present 😊 @KahnwaldMaurice and @KC_Oost managed to have incredible insight into a very fast and inaccessible process: human intestinal regeneration. “Dynamics and plasticity of stem cells in the regenerating human colonic epithelium” biorxiv.org/content/10.110…


Kathleen Shah Reposted

Highly recommend this book to anyone interested in the biology of diseases. A systematic explanation of what, how, and why, can go wrong resulting in a particular spectrum of human disorders. The book is a foundation for a new branch of biomedical science.

Why do we get certain diseases whereas others do not exist? This new book builds a foundation for systems medicine. Starting from basic laws, it derives why hormone, immune and aging circuits are built the way the are, culminating in a periodic table of diseases.

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Kathleen Shah Reposted

UK association with #HorizonEurope is finally confirmed! 🎉This agreement is thanks to the hard work of many people working to show the value of international collaboration during negotiations 🇬🇧🇪🇺

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Kathleen Shah Reposted

Are you interested in tissue immunology? Come join our lab!! 😊We have a postdoc position available to investigate links between skin immune-surveillance and the peripheral nervous system. Find advert here: imperial.ac.uk/jobs/descripti… or at jobs.ac.uk or Nature jobs.


Kathleen Shah Reposted

Q. What happens if YAP1 is lacking from mesenchymal cells? A. Vascular failure. Why? Because vessel formation needs YAP1-dependent tissue stiffening. science.org/doi/10.1126/sc…


Kathleen Shah Reposted

It took 10 years, 500 scientists, and €600 million, and now the Human Brain Project — one of the biggest research endeavours ever funded by the European Union — is coming to an end. How did it go? go.nature.com/3OKVRhN


Kathleen Shah Reposted

I'm very happy to share our work, which shows the importance of aryl hydrocarbon receptor signalling in lung endothelial cells to promote tissue tolerance and protection against respiratory virus infection. nature.com/articles/s4158…


Kathleen Shah Reposted

Congratulations Andreas Wack and colleagues very important findings in ⁦@Nature⁩ Endothelial AHR activity prevents lung barrier disruption in viral infection | Nature nature.com/articles/s4158…


Kathleen Shah Reposted

An outstanding review of how these 3 systems—gut microbiome, nervous system, and immunity—interact cell.com/immunity/fullt… @ImmunityCP

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Kathleen Shah Reposted

Online now: Lymph node sharing between pancreas, gut, and liver leads to immune crosstalk and regulation of pancreatic autoimmunity dlvr.it/StMrQR


Kathleen Shah Reposted

I am very excited to share with you that my very first review on cancer cell plasticity, written together with Kevin Bévant, is published in @NatureCancer Truly thankful @CedricBlanpain for this challenge and great opportunity. @evomet_itn go.nature.com/3KvfjxJ


Kathleen Shah Reposted

🚨🚨We are proud to release our latest review on MUC2 in Seminars in Immunology. 24/7, this workhorse mucin tirelessly facilitates peace between our microbiota and immune system, largely via its glycome @SFGlycobiology However, this is not your "run-of-the-mill" review.... (1/4)

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Kathleen Shah Reposted

Extraordinary news in a preprint on condensed matter physics: Lee, et al. claim to have made the first material that is a superconductor at ambient temperature and pressure. If true, will change the world. arxiv.org/abs/2307.12008 arxiv.org/abs/2307.12037

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Kathleen Shah Reposted

Rethink your fixative for immunofluorescence !science.org/doi/10.1126/sc…


Kathleen Shah Reposted

More evidence in @Nature today that cancer is a phenomenon of injury & regeneration gone awry. And a new model of lepidic type adenocarcinoma (previously called bronchioloalveolar carcinoma) generated via oncogene targeting to a distinct cell of origin. nature.com/articles/d4158…


Kathleen Shah Reposted

Another powerful study highlighting that macrophages are an untapped source of therapeutic targets with new data showing the role of macrophages atrial fibrillation science.org/doi/10.1126/sc…


Kathleen Shah Reposted

2/ In the 1st story, Laura Pikkupeura, @bressan_raul and Jordi Guiu now @GuiuLab with @albin_san lab performed a comprehensive characterization of fetal and adult small intestine and intestinal organoids. science.org/doi/10.1126/sc…


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