Josephine K. Liwang
@josephineliwangPhD candidate 👩🏻🔬🧠 @yongsookimlab | @NIH IRTA, @EmoryUniversity alum | I like glia, neurodevelopment & microscopy🔬 | 🐕🐕🐕 mom
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A few weeks ago, I had the wonderful opportunity to present at the 10th annual NIH BRAIN Initiative meeting as a Scholar Spotlight awardee, along with a great group of people! Thank you for organizing this event @cllantz & Dr. Ngai! 📸: Lesnick Photo @USBrainAlliance #studyBRAIN
CNS macrophage contributions to myelin health onlinelibrary.wiley.com/doi/full/10.11…
✅it out! Immune cells (#microglia) shape angiogenesis in the developing brain 🧠 and with infection, can lead to #germinalmatrixhemorrhage. Proud of lead author @JiapeiChen @UCSFGradDiv who drove this story from the start and I got to watch her grow. nature.com/articles/s4159…
It's Spooky Brain season! 🧠👻🧟♂️ Staining in the prefrontal cortex with 🟣SMI-32 for neurons (one of the best markers for pyramidal cells I've seen), 🟢Iba1 for microglia, and 🔵Dapi for nuclei! Happy #FluorescenceFriday!🔬
Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1 biorxiv.org/content/10.110…
It's out! See the paper for all things brainstem fmri, brainstem-cortex relationships, neuromodulatory receptors, functional gradients, moody colourmaps, wonderbread plots, the word "umwelt", 6 more raphe nuclei than you thought there were,
Integrating brainstem and cortical functional architectures | nature.com/articles/s4159… led by @JustineYHansen in @NatureNeuro 400 cortical regions + 58 brainstem nuclei. Lesgo 🤘🕶️⤵️
26 years after Larry Swanson emphasized “the amygdala is neither a structural or functional unit” we used sn-RNAseq to answer the question: “What is the [primate] amygdala?” Check out the preprint 👇 biorxiv.org/content/10.110…
Congrats @FaeKronman & team!!! So happy this work is finally published @NatureComms 🥳 Thanks for allowing me to be a part of it 🤍
Developmental Common Coordinate Framework (DevCCF) for developing mouse brain atlases is out. nature.com/articles/s4146… It features MRI and light-sheet co-registered templates and 3D anatomical labels based on developmental ontology from embryonic to adult ages
Single-cell RNA sequencing to profile 215,680 *living* human #microglia across neurological diseases and CNS regions identifies disease-enriched subsets and tool compounds recapitulating microglial states @TuddenhamJohn @HaageVc @MarikoTaga nature.com/articles/s4159…
🚨📢 Excited to announce our new paper in Science Advances! We’ve uncovered how Shank3 mutations affect myelination in an autism mouse model and human iPSC-derived OPCs. 🧠💡 Check it out! science.org/doi/10.1126/sc…
Very excited to share our pre-print and my thesis work on the postnatal development of astrocyte regional heterogeneity, which includes an integrated dataset of >1.4 million single nuclei transcriptomes in mouse and marmoset brains (now available online)! biorxiv.org/content/10.110…
I guess that's why they're called pyramidal neurons! #FluorescenceFriday
Back from SfN & want to thank everyone who said hi, shared their science, and/or shared a slice of deep dish pizza with me in Chicago! Lucky to be a part of so many wonderful communities! 🧠✨ (Also, you know I had to draw Doc Pigeon at the airport!) #SfN24 #SfNPigeon
First @SfNtweets nanosymposium presentation in the books! 👩🏻🏫🧠🥳 Thank you to all @yongsookimlab members, the TPDA committee, & @DSHB_antibodies for your support!
Excited to share that we have a new preprint online!! 🙌 #microglia #liveimaging #neonatal #aging biorxiv.org/content/10.110…
Congrats Steffy @BManjila on your long-awaited paper release! There are still so many unknown frontiers involving the brain and how it processes information, so this is a really interesting adventure 🧠 ⬇️
Our first attempt to understand the anatomy and function of the dorsal endopiriform as a part of the claustrum complex, by @BManjila and others. biorxiv.org/content/10.110…
5 years ago, on the heels of 28andMe, our team designed a new precision imaging experiment: scanning an individual’s brain throughout her entire pregnancy. We are excited to share that these findings are out today in @NatureNeuro! nature.com/articles/s4159…
Just published @Nature How fibrin drives brain inflammation in acute and #LongCovid and that a monoclonal antibody to fibrin protects against microglial activation nature.com/articles/s4158… @AkassoglouLab @GladstoneInst
Happy to share the final version of our paper, online today @Nature! We find that adolescent oligodendrogenesis is required for proper circuit maturation and functionally limits experience-dependent neuronal plasticity in adult visual cortex. 1/ nature.com/articles/s4158…
Out now! “Schwann cell-secreted PGE2 promotes sensory neuron excitability during development.” Published online today @CellCellPress authors.elsevier.com/a/1jbBiL7PXqRXI
Our special August issue focused on glia is now live! nature.com/neuro/volumes/…
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