Cancer Stem Cell News
@cancerscnewsAn online resource for the cancer stem cell and progenitor cell research community. Part of the @STEMCELLTech Science News service.
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We know you're interested in cancer research, but did you know that Science News by @STEMCELLTech offers an additional 19 newsletters and X accounts across a variety of immunology and cell biology fields? 🤩 Check it out now! 👇 bit.ly/3IqsZIV
📈 Scientists demonstrate that USP10 positively regulates CD44 protein levels and its downstream actions. Its overexpression led to enhanced cluster tumor cell formation, #stemness, and metastasis in #BreastCancer cells. @Biochem_Journal | 👉 bit.ly/3OmASlu
📢 Scientists introduced an effective approach to isolate and culture liver cancer stem cells from human primary #LiverCancer, leveraging mouse embryonic #fibroblasts as feeder cells in conjunction with using defined medium. 👉 bit.ly/4i0bVdc
💡 The eradication of H. pylori reduces #GastricCancer risk, but post-eradication surveillance is essential. Understanding the fundamental mechanisms of gastric #carcinogenesis is key to advancing treatment. 👓 bit.ly/490HYpp
⛔ Scientists evaluated 830 #flavonoids from the PubChem database against five ALDH isoforms using computational methods to identify potent inhibitors against #cancer stem cell protection and maintenance. 👉 bit.ly/4fPyRdq
🧠 Scientists used a systemic theoretical perspective to integrate experimental knowledge into a core endogenous network model for #glioma. 💡 They found two stable states corresponding to #astrocytic- and oligodendrocytic-like tumor cells. @scireports | go.nature.com/4hEu4NP
📊 Researchers revealed that aberrant pyruvate dehydrogenase kinase 1 expression was closely related to aerobic glycolysis in #squamous intraepithelial lesions and poor survival in patients with #cervical cancer. 🔓 bit.ly/3O52T0Y
💉 Investigators at @NagoyaUniv reported the development of a lysine-specific demethylase inhibitor, S2172. 🧠 S2172 effectively suppressed #LSD1 enzymatic activity, resulting in the depletion of cell growth of #glioma stem cells. 🔗 go.nature.com/4enoHQc
🧫 Researchers enabled highly efficient capture and in situ phenotypic analysis of circulating #tumor cells through enhanced and tunable on-chip immunoaffinity binding. 👓 Learn more at @acsnano! | bit.ly/4foKKr5
🧠 In this study, #cytotoxicity of the B2E5-antibody drug conjugate was evaluated by both adding it to cultured #glioblastoma-initiating cells (GIC) and injecting it into GIC tumor-bearing brains. 👉 @NeuroOnc | bit.ly/4hFcSYh
Dr. Michaela Reissland (@crypt_tales) and team at @MPI_MolGen discovered that the deubiquitylating enzyme USP10 stabilized β-Catenin specifically in APC-truncated #ColorectalCancer. @oncogenejournal | go.nature.com/3UHRwzH
Start your day with the most difficult tasks instead of putting them off. 💪 This ensures you make progress on them, and can free up the rest of your day for more exciting work. Increase your productivity with these habits. @STEMCELLTech bit.ly/3Tpp3y2
🧫 To study the spatial interactions among cancer and non-cancer cells, we here examined a cohort of 131 #tumor sections from 78 cases across 6 #cancer types by Visium spatial transcriptomics. 🔓 @Nature | go.nature.com/3Yvb0sw
🔎 G protein subunit Gamma 5 has been found to be involved in regulating glioma progression. In this study, #glioblastoma cell proliferation, apoptosis, invasion, and stemness were assessed. 📖 @SciReports | go.nature.com/4hDNQJ3
Join Genmab, AstraZeneca, Gilead Sciences, and more in December at the Tumour Models London Summit! Check out the event guide now for full session and speaker details: ter.li/lshqdo 10% Discount Code: CANCERSTEMCELL10
💊 Scientists reported a self-assembled nano-prodrug composed of aldehyde dehydrogenases activatable photosensitizer and disulfide-linked all-trans retinoic acid for diagnosis and targeted treatment of #CSCs enriched #tumors. 📖 @NatureComms | go.nature.com/40AgZyO
🧠 Scientists at @istitutotumori demonstrated that #hiPSC-neural stem/progenitor cells adopted a radial #glia-associated signature, sharing key epigenetic and transcriptional characteristics with human fetal #neural stem cells. 🔓 @NatureComms | go.nature.com/4eeRI0r
B2E5 demonstrated a high affinity for human Epithelial V-like antigen 1 (EVA1) and effectively killed both EVA1-expressing cell lines and glioblastoma-initiating cells in culture. bit.ly/3UsTHag
#NakedMoleRats are famously long lived. Could their retrotransposons hold the key? 🗝️ To find out, Ariel University researchers dug into the animals "retrobiome". Check out their results! bit.ly/4f30FLB
Thrilled to share our latest review with @JudithAgudo1 on the unique immune resistance mechanisms of #CancerStemCells in solid tumors! Explore how these insights are reshaping cancer therapy approaches. #Immunology #CancerResearch #CancerImmunotherapy"
Huge congratulations on this milestone! We highly encourage our followers to check out this paper and its #tweetorial 👇
Really excited to finally share my PhD work out in @Nature today on #polyclonal interactions in #intestinal tumour formation, and pleased to have collaborated with @KenLauLab on their paper in the same issue of the journal. nature.com/articles/s4158…. A long 🧵
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