Lee Lab
@anuobigDiscovering #biological_physics by inventing new #optics, #computation, #materials_science, and #fluid_dynamics techniques.
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Thrilled to received the inaugural #AEA seed grant (Tranche 1- Medical Science stream)! Grateful for AEA support that will accelerate our work on ANU-Spatial Adaptive Imaging for #singlecellspatial technologies @JCSMR @ourANU @ResearchAnu
#JCSMR led Spatial Adaptive Imaging (SAI) Project developed by @anuobig in collaboration with @GarvanInstitute was among the 10 medical science projects chosen to bridge the “valley of death” by Australian Economic Accelerator #AEA Tranche One Grant. Read: bit.ly/3R19YC6
Orii and Tanimoto @YCU_koho study the structural mechanics of #microtubule and #actin cytoskeletons using high-force intracellular magnetic tweezers. The measurements directly reveal the integrated nature of the two cytoskeletons throughout the cytoplasm hubs.la/Q02Yn83r0
Graham was a much under appreciated scientist with whit and insight that was just delightful. journals.biologists.com/jcs/article/13…
We think that all memory is stored in the brain. But our study published today in @NatureComms shows that all cells—even kidney cells—can count, detect patterns, store memories, and do so similarly to brain cells. My first (co)corresponding author paper!🧵nature.com/articles/s4146…
#OPENACCESS: Jafarinia et al. develop a stochastic model to explore YAP phosphorylation dynamics in integrin adhesions, highlighting how adhesion size, spatial distribution, lifetime, and YAP diffusion/binding rates modulate YAP phosphorylation levels. ow.ly/b2s250U0vNn
nature.com/articles/s4158… Congratulations to my good friend Keunwoo Ryu and the Craig Thompson lab on uncovering metabolically distinct mitochondrial subpopulations. Really cool cell biology Keun!!
Arslan, F. N., Eckert, J., Schmidt, T., & Heisenberg, C. P. (2021). Holding it together: when cadherin meets cadherin. Biophysical journal, 120(19), 4182–4192. #EpithelialMechanicsReview sciencedirect.com/science/articl….
Cell pores get "salty": salt ions near the #membrane provide extra potential to promote the pore initiation. Via @CQU1929 aippub.org/3WxMrKw
From MBoC CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover @mace_em data identify a role for CD56 in regulating human NK cell migration through modulation of actin dynamics and integrin turnover. doi.org/10.1091/mbc.E2…
And it’s out - our special issue on ‘Imaging Cell Architecture and Dynamics’! Huge thanks to everyone - authors, reviewers and editors (@EM_STP and @guijacquemet) - who contributed! 🙌 #imaging #cellbiology #microscopy
Our Special Issue on Imaging Cell Architecture and Dynamics is now complete. You can explore our ToC here: journals.biologists.com/jcs/issue/137/… ‘Breaking symmetry’ from @AntaraC9 was the winning image from our cover competition with @focalplane_jcs The image is a MEF labelled with phalloidin…
First mini-review/commentary from the Tharp lab... discussing optimizations/mechanisms that might aid pre-clinical discoveries against cancer. bpspubs.onlinelibrary.wiley.com/doi/epdf/10.11…
Did you know that #macrophages (magenta) talk to #fibroblasts (green) and that influences the regenerative outcome after a spinal cord injury? They actually slide and circle around them! Part of our last #preprint (Fixed). Credit to @ozuozge
Life at low and high Reynolds numbers! A great, wide ranging talk from David R Nelson @harvardphysics on how fluid flows can affect growth of microbial populations, from oceanic simulations 🌊 to lab microorganisms 🦠
Our lab is welcoming applications for this unique fellowship @embl, especially surrounding light microscopy, automation and AI. Please reach out to find out more!
Time to accelerate!⏱️ 1 month left to apply for EMBL ARISE2 fellowship program. Are you interested in the development or improvement of technologies on life science research? #ARISE2 trains you to become a future science infrastructure leader. Apply now! embl.org/training/arise…
Active hydrodynamics is a powerful approach to describe cellular aggregates. But how to deal with intrinsically present fluctuations? Subhadip has put forward this beautiful work on fluctuating hydrodynamics to derive transport coefficients of diffusivity and conductivity!
Transport in cellular aggregates described by fluctuating hydrodynamics, Subhadip Chakraborti and Vasily Zaburdaev @VasilyZaburdaev @MPZ_PhysMed @UniFAU @EBM_research #Biophysics #Networks #StatisticalPhysics go.aps.org/3BUkQwi
Noboru shows a 'MD simulation'. ATG9 vesicles move freely due to thermodynamic fluctuations. When they contact the OPTN droplet in the center of the screen, the ATG9 vesicles are captured and anchored to the droplet due to the wetting effect (Mizushima et al. unpublished)
Our new paper has been published in @embojournal! We demonstrated that capillary forces by autophagy receptor droplets on mitochondria is important for mitochondrial recognition and mitophagy. Congratulations, Zi! embopress.org/doi/full/10.10…
Looking for a postdoc position in nuclear #mechanobiology, with a strong interest in microfluidics, device design, fluorescence microscopy, and image analysis? Check out our opening: bme.cornell.edu/bme/job-openin… If you are attending #BMES2024, we can meet there. Please RT.
Our latest issue just dropped. And it's special! A high-density assortment of essays primer and reviews on #physics in #biology! Check it out! cell.com/current-biolog…
‘Be water my friend’ Intercellular fluid dynamics in tissue morphogenesis @CurrentBiology with @maitrejl and @Descroix16, we are happy to present you our new review: doi.org/10.1016/j.cub.…
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Who to follow
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Alvaro Crevenna
@AlvaroCrevenna -
Mechanobiology Institute
@MBIsg -
R. Wedlich-Soldner @RWedlichSoldner.bsky.social
@RolandSoldner -
Alfred Millett-Sikking
@amsikking -
Light Microscopy Aus
@LightMicroAus -
Adel Al Jord
@AdelAlJord -
Dr. Samantha Stehbens PhD
@SamStehbens -
Hannah Heil
@Hannah_SuperRes -
QIAN (Peter) SU
@QianPeterSu -
Biological Optical Microscopy Platform
@BOMPUoM -
Dr Alex Payne-Dwyer
@alex_paynedwyer -
Nick Condon
@DrNickCondon -
Makoto Kamei
@ADLmicroimaging -
Pietro Ridone
@PietroRidone -
Niall Geoghegan
@geogphotog
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