Tonya Zeczycki
@Zeczycki_Labenzymologist | physical biochemist | director, BSOM's MS Core Facilities | studies IDPs, allostery, and redox in neurodegenerative diseases | opinions my own.
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Check out the 2024 Emerging Investigators Issue for @J_ASMS The future of mass spectrometry is definitely in good hands!! pubs.acs.org/toc/jamsef/35/…
Our paper describing a new method (FLiP-MS) for the global profiling of protein complex dynamics is out @NatureBiotech ! Read here👉: doi.org/10.1038/s41587… 🔬 Highlights: - Uses an experimental library of peptide markers integrated with a structural proteomics workflow. -…
Rethink the analysis of DDA data! Blurring the boundary between DDA, WWA, and DIA, #MSFragger-DDA+ Enhances Peptide Identification Sensitivity with Full Isolation Window Search. Fully integrated in #FragPipe, simply annotate your DDA files as DDA+ and RUN. biorxiv.org/content/10.110…
The synuclein seeding assays are not enough to diagnose Parkinson and to differentiate it from PSP and MSA. Dr Edwin Jabbari @ucl makes a convincing argument that kinetics matter and combination assays will be the path forward. A combo assay that includes a 4R Tau assay has great…
Working with my lab peeps and collaborator this week has, once again, reminded me why I love what I do and that I truly have the best "job" in the world.
I try not to brag about our papers when they come out, but for this one I make an exception. It is a clinical trial showing that our new drug combination is effective in pain patients. It will be published in Frontiers in Pain Research. @ECUBrodySOM @ECUResearch @RLSFoundation
Happy Proteomics Day!! 30 years ago today Marc said the word, and we totally knew that when we sat down with him and recorded the kick off episode of this new @us_hupo sponsored season of THE Proteomics Show. proteomicsnews.blogspot.com/2024/09/happy-…
We are thrilled to share our latest preprint on the Anti-Müllerian Hormone and its unique signaling pathway. Our first ever cryo-EM structure represents a breakthrough over 40 years in the making. 🧬🔍 (@drewhow66) Check out our findings here: biorxiv.org/content/10.110… 1/10
👋A.M.A.Z.I.N.G. 👋 Refresher paper on Understanding isotopes, isomers, and isobars in mass spectrometry: sciencedirect.com/science/articl… Checkout! #isotope #isobar #isomer #massspec #metabolomics #multiomics #proteomics
Very excited to see work from Hanna Budayeva included in this special issue of @JProteomeRes Hanna has done a fantastic job leading our chemoproteomics efforts over the last few years - this story is just one of the exciting things her group is working on! Check out this issue!
The latest issue of Journal of Proteome Research is live! On the cover: "Celebrating Women in Proteomics and Metabolomics" Read it here: pubs.acs.org/doi/full/10.10…
Important to de-stigmatize mental health efforts for Graduate Students. How PhD students and other academics are fighting the mental-health crisis in science nature.com/articles/d4158…
"I am a huge proponent of do-it-together biology, not do-it-yourself." Photos and interview with @ATinyGreenCell in @AsimovPress Worth updating your mental model on amateur biology. There's an important future being crafted in this spare bedroom lab.
Humbled and honored to have been awarded this: rlsfoundation.blogspot.com/2024/07/2024-e… I hope I can continue meeting the expectations! @ECUBrodySOM @ECUResearch @ECU_Neuro @EastCarolina @RLSFoundation
Please RT: We have Senior Scientist, Postdoctoral Researcher and PhD student positions available in our lab focusing on the role of Hsp70 PTMs in a variety of processes including cancer, aging and host-pathogen interactions. Please see: trumanlab.org/contact #hsp70 #chaperones
Mass spectrometrist with an inbox full of "overqualified" emails looking for work! proteomicsnews.blogspot.com/2024/06/could-…
Wiggles, jiggles, and dangly bits? What more can you ask for? Awesome paper from @idpemery with the @alexholehouse lab....
Do you like IDPs? Do you like phosphorylation? Check out my first postdoc paper (w/ @alexholehouse) now on bioRxiv: biorxiv.org/content/10.110…. We optimized pSer and pThr parameters for all-atom simulations using the ABSINTH-OPLS/AA implicit solvent model (1/7).
Comprehensive Overview of Bottom-Up Proteomics Using Mass Spectrometry | ACS Measurement Science Au pubs.acs.org/doi/10.1021/ac…
Are you interested in FDR in proteomics? @wenbostar has a fantastic preprint out about the use of entrapment. Excited to see lots of content at #asms2024 around this topic. biorxiv.org/content/10.110… @thabangh
We have to start Pride Month with the Divas of Dance
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