Marcus Goncalves
@MarcusDGonMD/PhD Endocrinologist and scientist. Cancer metabolism, cachexia, insulin, PI3K, diabetes, obesity. GI Villi lover. Metabolic Consulting. NYJ/NYY/NYCFC fan.
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Whoops! Hidden data on obesity prospect wipe $12B off Amgen market cap @FierceBiotech - of course bone density goes down with weight loss! C’mon now. fiercebiotech.com/biotech/hidden…
There’s bipartisan support to tackle chronic diseases related to ultra-processed foods. @DrCaliff_FDA says we need higher-quality scientific research to inform better decisions. Let’s do this! @IRPatNIH @NIDDKgov statnews.com/2024/11/15/ult…
🚨 BREAKING: For the first time ever, we have official international LOW-CARB HEALTHCARE guidelines for managing Type 1 Diabetes! 🚨 Created by experts & people living with T1D, these guidelines empower healthcare professionals & patients to safely navigate therapeutic carb…
Awesome paper from Jack Taunton’s lab @UCSF : Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation | Nature nature.com/articles/s4158…
ACVR2B polymorphism, Adiponectin, and GDF-15 levels as biomarkers for cachexia in gastrointestinal cancer | Scientific Reports nature.com/articles/s4159…
50 people in line at Penn station in NYC
A little kindness (& a dozen) go a long way! 🍩😁 In celebration of #WorldKindnessDay tomorrow, we’re giving a FREE Original Glazed® dozen to the First 500 people to visit each shop! 😊 For full details visit krispykreme.com/offers/worldki…
Are you a Phd student or post doc? Planning on going to a metabolism conference in 2025? @lifemetabolism2 have FOUR 700$ travel prizes available to help. Three generously sponsored by @SableSys deadline 24th DEC 2024. Very short form to apply. academic.oup.com/lifemeta/pages…
Metabolic disruption exacerbates intestinal damage during sleep deprivation by abolishing HIF1α-mediated repair @CellReports cell.com/cell-reports/f…
JCI - Melanocortin-4 receptor antagonist TCMCB07 alleviates chemotherapy-induced anorexia and weight loss in rats jci.org/articles/view/…
More data that C-peptide is associated with an increased risk of invasive breast cancer risk (top vs. bottom quartile, odds ratio = 1.46, 95% CI: 1.12–1.91) nature.com/articles/s4152…
Excited to reveal that “VPS4A is the selective receptor for lipophagy in mice and humans” cell.com/molecular-cell…
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria | Nature nature.com/articles/s4158…
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