Alessandro Gozzi
@Gozzi_AleSenior scientist @IITalk 🧠 🐁 Neuroimaging, brain (dys)connectivity and autism @ERCGrantees
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How do cortical perturbations affect fMRI connectivity? Not necessarily as one would expect! Our new work @NatureComms shows that cortical inactivation may unexpectedly INCREASE fMRI connectivity! rdcu.be/cHKie 🧵below explains how. Spoiler: δ oscillations are key! 1/n
Remember back in 2022, when we didn't need to worry about a 2nd Trump Presidency, but were concerned about how many participants it would take to map links between personality & brain activity? (cf work by @smarek0502 & @ndosenbach) We have good news 👇 nature.com/articles/s4200…
This is wild and futuristic. A virtual lab comprised of multiple (5) #AI agents designed potent nanobodies vs #SARSCoV2 with minimal human oversight. biorxiv.org/content/10.110… @james_y_zou @KyleWSwanson @czbiohub @Stanford
Could embracing analytical variability in neuroimaging be the key to more robust and generalizable scientific discoveries? Check out the latest by @g_kiar, @tingster, @neuro_data, @TristanGlatard and Jeanette Mumford for insights: rdcu.be/dZ0HA nature.com/articles/s4146…
Very proud - @sara_pmonteiro (co-supervised by @patricia_mpfig) developed a new experimental setup for higher resolution (>x10 ) CBF mapping in rodents, with sequences by our collaborators Emmanuel Barbier and Lydiane Hirschler shorturl.at/YIaC3 Setup designs are provided!
I am absolutely stoked to share our new study on multiscale neural dynamics across species and behaviour + network simulations exploring their benefits! The best lab going around! Captained by THE @jmacshine 🙌
Now online! Multiscale organization of neuronal activity unifies scale-dependent theories of brain function dlvr.it/TFwFR7
If you are looking for a method that can integrate across symmetric correlation/covariance matrices (anything network neuro), we got you! So excited to see this out and thank you to the reviewers for helping us make it better (and for upping my multivariate stats game😆)! 1/n
Baracchini and Yu et al. present a network neuroscience tutorial for covSTATIS, a method that identifies structured patterns in multi-table data: doi.org/10.52294/001c.… @giuliaabaracc @juchiyu @derek__beaton @Nathan_Spreng @mallarchkrvrty1 @fMRI_today @OHBM
Program available now 🔍check in the imgs #BrainModes2024 Bilbao Register today🎟️Nov. 18 - 21, 2024 brainmodes-bilbao-2024.eu/#registration Since its inception /2007 #BrainModes has been a beacon for the neuroscience community drawing attention to the intricate dynamics of brain functionality
🎊 new preprint Super excited about this data because almost 30 years 😱after our series of papers on dopamine, NMDA, and schizophrenia came out, we may have mechanistic insight about latent presentation of psychosis and abnormalities in dopamine dynamics in schizophrenia 🧵1/n
Reductions of Grin2a in adolescent dopamine neurons confers aberrant salience and related psychosis phenotype biorxiv.org/cgi/content/sh… #biorxiv_neursci
New work from @samardzija_anja and team. Instead of using CPM to identify networks, networks are predefined and used to evaluate external measures. This allows standardized tests (or any measure) to be evaluate in terms of the networks they rely upon. biorxiv.org/content/10.110…
If you are interested in deep brain 2p imaging, check out our new work on aberration-corrected long microendoscopes (length > 6 mm)! Published as a Reviewed Preprint in @eLife! Thanks to all the authors! elifesciences.org/reviewed-prepr…
Our latest PP led by @IvaIlioska, in collab. w/ @NSB_Lab @DondersInst We use normative modelling to characterise the inter-individual variability of FC alterations in people with autism from individual edges to macroscale networks: tinyurl.com/mr4673cw
Excited to deliver Release 3 of The Open MEG Archives:🧠🧲 644 participants ∣ over 150 hrs of task-free recordings ∣ incl. Parkinson’s disease, ADHD, chronic pain + 444 healthy controls ∣ defaced structural MRI volumes ∣ individual questionnaire data. mcgill.ca/bic/neuroinfor…
Exciting new work by @loopyluppi &⭐️coauthors showing that in 👨🦰🐵🐭 large-scale modelling of fMRI activity is largely improved by accounting for *competitive* interactions between areas (i.e. assuming that when one area is active, another quiets down) ➡️tinyurl.com/2wsr4nnf
After being years in the making, our paper investigating aging and Alzheimer's disease (of course, using 🐭🧠🧲) is finally out in @molpsychiatry!! A mini-thread below, but I warn you, the figures are...big :D nature.com/articles/s4138…
Curious about human brain development through an animal model? 🧠🐒Check out our new preprint on Brain Charts of the Rhesus Macaque Lifespan! We've mapped normative trajectories for macaque brains using 1.5k MRI scans from PRIME-DE and collaborators! biorxiv.org/content/10.110…
Functional MRI of imprinting in awake chicks offers insights into the neural networks for memory acquisition and storage at birth, opening new avenues for noninvasive, neuro-cognitive studies: nature.com/articles/s4200… @BehrooziMehdi @ElenaLorenzi3 @gVallortigara @Gozzi_Ale
" I don't like honours." - Richard Feynman
Integrating brainstem and cortical functional architectures | nature.com/articles/s4159… led by @JustineYHansen in @NatureNeuro 400 cortical regions + 58 brainstem nuclei. Lesgo 🤘🕶️⤵️
Was a pleasure to chat with @AHalladay212 at the @AutismScienceFd on their podcast about our latest research (molecularautism.biomedcentral.com/articles/10.11…) on early developing heterogeneity in autism. @LAND_IIT @InesSeverino_ @IITalk @ERC_Research blubrry.com/asfpodcast/137…
Neuroscientists care about the causes of behavior, while ethologists care about the consequences. These approaches need to merge for us to understand human behavior and its associated suffering. Dorian Battivelli, Fan Zhengxiao, Hu Hailan, and I lay out the why and what.
The study of behavior requires a combination of the ethology and neuroscience approaches. The latest publication from the Gross group outlines the tools needed to optimise this holistic approach to study fear, aggression and dominance behaviours: nature.com/articles/s4158…
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