@DorotheeKern Profile picture

Dorothee Kern

@DorotheeKern

Professor at Brandeis University and HHMI. Using biophysical techniques to unravel the dynamic personality of proteins and study their evolution.

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Want to listen in this Friday at 2 pmEST how the dance of proteins dictates biology, and how we can take advantage of it for better treating disease ? Register for Free! #proteins #action #dynamics

Webinar Alert: October 6, 2:00 PM EST Protein Dynamics - the Key for Biological Function, featuring Dr. Dorothee Kern and Dr. Lewis Kay. TPS webinars are always free. Register here: us06web.zoom.us/webinar/regist…

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Dorothee Kern Reposted

Webinar Alert: October 6, 2:00 PM EST Protein Dynamics - the Key for Biological Function, featuring Dr. Dorothee Kern and Dr. Lewis Kay. TPS webinars are always free. Register here: us06web.zoom.us/webinar/regist…

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Webinar - October 6, 2 - 4 p.m. EST; Featuring Lewis Kay and Dorothee Kern mailchi.mp/proteinsociety…


Thank you @Relay_Tx for the kind congrats and helping me to translate our biophysics research at @HHMI and @BrandeisU into novel drugs with unprecedented selectivity to cure patients! Dream team! 💪

We're thrilled to congratulate Relay Tx founder @DorotheeKern on her election to the @americanacad! Her incredible dedication to the advancement of protein dynamics for drug design is truly unmatched. Congratulations, Dr. Kern! 🌟

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Thank you to the incredible students, postdocs and colleagues that allowed me to work with them, and my family and friends for all the love and support for my crazy ideas.

Professor of Biochemistry Dorothee Kern has been elected to the prestigious American Academy of Arts and Sciences, which honors exceptionally accomplished individuals across a variety of disciplines. brandeis.edu/now/2023/april…



Thank you Julia, the credit all goes to my family, the Kern lab and my friends that have kept me happy, passionate and hungry.

So extremely proud of my Mom @DorotheeKern for this incredible accomplishment!!



Dorothee Kern Reposted

Research briefing: The mechanism of the simplest biological 24-hour clock go.nature.com/3K5lOHD


Our quest into the evolution of one of the most fundamental players in biology, biological 24- hour clock! Great team work by so talented and creative postdocs @HHMINEWS

Research briefing: The mechanism of the simplest biological 24-hour clock go.nature.com/3K5lOHD



Tackling the biggest obstacle in the fight against cancer, development of resistance to drugs. Here we reveal a solution: double-drugging, and how to best chose the best drug combination: A biophysical framework for double-drugging kinases biorxiv.org/content/10.110…


Dorothee Kern Reposted

OUR DOUBLE POLE QUEEN👑🇺🇸 @juliakernski with an incredible race in the Drammen City Sprints, finishing sixth overall!

Research briefing: The mechanism of the simplest biological 24-hour clock go.nature.com/3K5lOHD



What a great start by @juliakernski and Rosie to the World Championships! Huge congrats to our speeeedy 🚀🔥daughter to be the 8th fasted woman in the world.

Research briefing: The mechanism of the simplest biological 24-hour clock go.nature.com/3K5lOHD



Putting a story about the author to a research paper is a great idea, making science more touchable. Here Nadja @nadjjk23 is featured for her paper with @inhibrx

Meet the Author: Dr. Nadja Kern (@nadjjk23), a Scientist and @ECR at @inhibrx, is co-author of "INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses", recently published in #JITC. 1/6

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Impressive selectivity of a novel cancer therapy combining IL-2 action with targeting selectively cancer cells by @nadjjk23 and co. Must read!

I had so much fun working with the incredible team at @inhibrx on this publication and am excited to share our work on INBRX-120, a novel and tumoricidal effector cell specific IL-2 based therapeutic! 🎉



Exciting development with talented and passionate postdoc @HWaymentSteele who fiercely tackles my ambitious goal of predicting conformational substates, not just one structure. And it is working!!! Greatly explained in the thread. Nice collaboration with @sokrypton and Lucy

We report that simply clustering a MSA lets #AlphaFold predict multiple states of fold-switching proteins. We used this to screen for alt states in proteins without known fold-switching, and describe one such predicted novel state for the DsbE enzyme. 1/n tinyurl.com/4ewfxf7x



We did it again! Best chance for success in making better medicines (which is very difficult) is an outstanding work atmosphere where people are so happy working together and making a difference in the world. Congratulations team 🥇#work #science #team

We're extremely honored to share Relay Tx has been named this year's #1 Place to Work in MA by @BostonGlobe Our distinguished approach, uniquely collaborative people, & drive to help patients make up a culture owned by each of our employees. #workboston bit.ly/3Fi1fW0

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So enjoyable to talk to students, postdocs and my colleagues in person again at the protein Society meeting! Great passion and vibe

We're extremely honored to share Relay Tx has been named this year's #1 Place to Work in MA by @BostonGlobe Our distinguished approach, uniquely collaborative people, & drive to help patients make up a culture owned by each of our employees. #workboston bit.ly/3Fi1fW0

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Dorothee Kern Reposted

Couldn’t have asked for a more epic Easter weekend in Mammoth with family and friends 🤩 Powder and spring skiing, dreams do come true!


Dorothee Kern Reposted

Thank you so much @gdemeo for all of the support in high school and beyond! It wouldn’t have been possible without WHS supporting me all those years.

So proud of Olympic skier Julia Kern, an inspiring athlete from a wonderful family!

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Dorothee Kern Reposted

Celebrate #InternationalWomensDay by registering for the @PatsFoundation's Women in Sports virtual panel on 3/29. Hear from industry leaders & athletes who have paved the way: bit.ly/3sRNs2g


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