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🎉 Thrilled to see the latest version of #RepeatsDB, which now incorporates predictions on #AlphaFoldDB models, published in @NAR_Open This comes as a result of the efforts from @BioComputingUP, the #TRP community, @refract_rise and @ml4ngp 🔗📑 doi.org/10.1093/nar/gk…
We have several open positions in our lab. If you are passionate about proteins and AI, come join us at an excellent location at @CRGenomica @the_prbb ! aiproteindesign.com/jointhelab
Excited to share our new paper in @PNASNews! 🚀 Halofilins shape archaeal cells during cell-type shifting. For details, check out Alex's threads! Huge thanks to @PohlschroderLab, @SchmidLab, and great team at @BissonLab Read more: shorturl.at/tzNqn @MPI_Bio
New paper online @PNASNews! Great collab with @Vikram_Alva, @PohlschroderLab, @SchmidLab and inspiring team work within the Bisson lab. PNAS: shorturl.at/tzNqn Preprint: shorturl.at/Wi58N Blurb: shorturl.at/vMZsZ highlights below (1/4)
Our latest manuscript "Understanding epistatic networks in the B1 β-lactamases through coevolutionary statistical modeling and deep mutational scanning" is out @NatureComms It is a great collaboration with Francesco Zamponi and Martin Weigt! nature.com/articles/s4146…
🔔#OriginOfLife digest — Aug 26 30 new papers, 3 by @oolen_org members — artificial chemistry (@colemathis__) — cellular automaton — habitable zone — technosignatures — protocells — assembly theory (@AmitKahana) — heat flows (Schmid, Matreux) — TRAPPIST-1 buttondown.com/ooldigest/arch…
Qinwen Queen of Paris! 👑🥇 Qinwen Zheng becomes the first Chinese player to ever win a singles gold medal at the Olympic Tennis Event! #Paris2024 | #Olympics | #tennis
1: Excited to share our latest work on the links between evolutionary rate, expression level, and genetic association with polygenic traits! We analyzed 4,576 traits to reveal how natural selection shapes these traits. academic.oup.com/mbe/article/41…
Evolutionary graph theory beyond single mutation dynamics: on how network-structured populations cross fitness landscapes academic.oup.com/genetics/artic…
Thrilled to share our manuscript on bacterial histone HBb from Bdellovibrio in @NAR_Open! We report DNA-bound HBb structures, showing its DNA bending properties. With Birte Hernandez Alvarez, @DameLab, Yimin Hu, @SammyBoterhammy, @MPI_Bio, @LeidenScience academic.oup.com/nar/advance-ar…
I'm hiring a postdoc, for bioinformatics work on amino acid substitution models. I think they are key for understanding biophysics of selection on proteins, mutation patterns, and ancient life, as well as improving phylogenetic methods. evol.mcmaster.ca/brian/evoldir/…
There are still some free slots at IOoL24! Deadline is extended to June 21st. It's an excellent occasion to present your work or to adress a topic/ideas in origins of life studies, come and join. :) Open to all early-career researchers in OoL. @oolen_org
🔔#OriginOfLife digest — June 10 20 new papers — open-ended evolution — bio-computation — habitable zone — RuBisCO subunit — polyextremophile — origin of information handling — martian polar cap — phanerozoic extinction — stromatolites buttondown.email/ooldigest/arch…
Latest work exploring the use of sequence representations for repeat detection, with @SDuninHorkawicz and Andrei @MPI_Bio biorxiv.org/content/10.110…
🔔#OriginOfLife digest — May 27 19 new papers, 1 by @oolen_org members — Mars Perseverance — Europa Clipper Mission — bio- & technosignatures — Mars sample return — diversification in chemistry (@YannickGeiger1) — autocatalytic networks (@joanarcxavier) 👉buttondown.email/ooldigest/arch…
🔔#OriginOfLife digest — May 13 13 new papers, 2 by @oolen_org members — Enceladus — technosignatures — molecular complexity — membrane structures (@SeanFJ) — metabolism & information (@artemyte) — Gaia hypothesis 👉buttondown.email/ooldigest/arch…
Our paper in @ScienceMagazine demonstrates that microevolutionary evolvability can predict evolutionary divergence across timescales spanning thousands to millions of years, linking evolution across these vast time intervals. Work led by @AgnesHolstad science.org/doi/10.1126/sc…
🔔#OriginOfLife digest — May 6 29 new papers, 2 by @oolen_org members — technosignatures — HWO science capabilities — ocean worlds — membrane permeability — UV damage — microfluidics (Verma) — TRAPPIST-1 — super-Earths (@tim_lichtenberg) — Ryugu buttondown.email/ooldigest/arch…
For the THIRD time, Nikola Jokić is the NBA’s Most Valuable Player 🃏
We just released the "protein design toolkit", integrating tools from Damietta, ProteinMPNN and OpenMM. An interactive tutorial is available at the server damietta.de. Recommended usage is described in the paper: doi.org/10.1093/nar/gk… and feedback is most welcome!
🔬Excited to share the revised version of our manuscript on the bacterial histone HBb from Bdellovibrio, led by Yimin Hu and @SammyBoterhammy A fantastic collaboration with Birte Hernandez Alvarez, @DameLab, @HartmannLab @MPI_Bio @LeidenScienceEN biorxiv.org/content/10.110…
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Who to follow
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MPI Bioinformatics Toolkit (MPI for Biology)
@mpitoolkit -
Livnat Afriat-Jurnou
@AfriatJurnou -
Saacnicteh Toledo-Patino
@SaacNicteh -
Tokuriki lab
@tokuriki_lab -
Klara Hlouchova lab
@KlaraH_lab -
Birte Hoecker
@BirteHoecker -
Charlotte Miton
@CharlotteMiton -
Bornberg Lab
@bornberglab -
Payal Nashier
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Lars Eicholt
@lacholt -
Joana Pereira
@Joana_MPereira -
Liam M. Longo
@LiamLongo -
Dan Kozome
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Vikram Alva
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Stanisław Dunin-Horkawicz
@SDuninHorkawicz
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