Bob Farese, Jr.
@BobFaresescientist, physician, photographer @FandWLab @ski_cellbio. Instagram https://t.co/CS5YVmNtaF
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Fixing BMP levels in the brain could someday help patients with #Alzheimer’s and frontotemporal #dementia, according to new research from HHMI Investigator @TobiWalther, @BobFarese, and members of their joint lab. Read more: hhmi.news/3YsA58w 👈
Now published, @SHUBHAM30642626 identifies PLD3/4 as synthesizing BMP, a lipid crucial for #lysosome #lipid #metabolism and #brain health sciencedirect.com/science/articl…
sciencedirect.com/science/articl… Interested in the #brain, #neurodegeneration and #lipids? See our new paper in @CellCellPress led by @SHUBHAM30642626 identifying PLD3/4 as enzymes that make a crucial lysosomal lipid. @FandWLab @SKI_CellBiology @TobiWalther
🗣️11 of MSK’s talented scientists & clinicians were selected to appear in an off-Broadway musical called “Lifeline." The show tells the story of the discovery of penicillin, weaving in “superbugs,” romance, & urgent messages about antibiotics, all set to music. A preview ⬇️
NYC friends! Go see @lifelinemusical before the end of September - a lyrical story about Sir Alexander Fleming and penicillin but also antimicrobial resistance. With a chorus of scientists (14/57 chorus members from @MSKCancerCenter!)
New work from @SHUBHAM30642626 on the mechanism of lysosomal #lipid degradation and its link to neuronal health @HHMINEWS @TobiWalther @BobFarese @SKI_CellBiology #CellBiology #neuro #Alzheimers
Thank you @aklymchenko and thank you @GerLipid and @Rachid_Thiam for the honor.
elifesciences.org/articles/88049 Fat without triglycerides? This fascinating story by @FandWLab former postdoc @MChitraju took some unexpected twists! The inability to store fat triggered energy expenditure. @TobiWalther @MET_HSPH
Big thanks to @TobiWalther @BobFarese @WredenbergLab and @NatalieKrahmer for presenting their published and unpublished data at the SRP Diabetes minisymposium at Nobel Forum. Lot’s of questions and discussions from an energetic crowd! @nikmejhert and I are really happy!
Don’t miss out! The upcoming SRP Diabetes symposium on energy metabolism, excellent speakers including @A_Amunts , @BobFarese , @NatalieKrahmer and @TobiWalther , Nobel Forum Campus Solna, September 25 at 1300!
My choice this week in @ScienceMagazine @BobFarese, @TobiWalther doi.org/10.1038/s41556…
Featured today by @MSKLibrary: The structure of #phosphatidylinositol remodeling #MBOAT7 reveals its catalytic mechanism and enables inhibitor identification: dx.doi.org/10.1038/s41467… @BobFarese @TobiWalther @xuewusui
Fantastic work by our former postdoc and now @Harvard faculty @JeeyunC - Congrats! @FandWLab @TobiWalther
🧋NEW: Chung et al. identify the Troyer syndrome protein spartin as a #lipophagy receptor for #lipiddroplet clearance in vitro and in vivo. @TobiWalther, @BobFarese, @FandWLab, @JeeyunC, @MCB_Harvard @SKI_CellBiology nature.com/articles/s4155…
Featured today by @MSKLibrary: Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis dx.doi.org/10.1038/s41467… @NatureComms @MET_HSPH @FandWLab @SKI_CellBiology @HarvardCellBio @xuewusui @ChiaWeiKennyLe1 @BobFarese @TobiWalther
Our paper on phospholipid remodeling enzyme MBOAT7, led by @KennyWang0208, is out. Kenny obtained a structure, elucidated how phospholipid headgroup specificity is attained, and identified lead compound inhibitors. @FandWLab @TobiWalther @SKI_CellBiology rdcu.be/dexrx
Glad to share our recent work on elucidating the inhibition mechanisms of triacylglycerol synthesis by small molecule inhibitors. Might shed light on drug development for treating metabolic syndrome and cancer. @FandWLab @BobFarese @TobiWalther @TAMUBCBP nature.com/articles/s4146…
New work from the lab! Congratulations @xuewusui , thanks Maofu Liao! @SKI_CellBiology @BobFarese
Glad to share our recent work on elucidating the inhibition mechanisms of triacylglycerol synthesis by small molecule inhibitors. Might shed light on drug development for treating metabolic syndrome and cancer. @FandWLab @BobFarese @TobiWalther @TAMUBCBP nature.com/articles/s4146…
Fred was an astute, passionate and kind colleague during our time in @HarvardCellBio I was glad to know him. We will greatly miss him and extend condolences to his family and friends.
Glad to share our recent work on elucidating the inhibition mechanisms of triacylglycerol synthesis by small molecule inhibitors. Might shed light on drug development for treating metabolic syndrome and cancer. @FandWLab @BobFarese @TobiWalther @TAMUBCBP nature.com/articles/s4146…
Work by our scientists @bond_lauram and @_AyonIbrahim showing the ER protein FIT2 is enigmatic but super important for cell health in vivo. @FandWLab @met_hsph @SKI_CellBiology pubmed.ncbi.nlm.nih.gov/36805337/
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