Bjørn Kwee
@BjornformaticsPhD student @Schumacher_Lab @NKI_nl | Bioinformatics | Cancer Immunology | High-Performance Computing
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Preprint alert 🚨🚨 Large language models can predict TCR - pMHC reactivity!🧬🔬 Proud to have worked on this project with @MariusMessemak1 and all other amazing co-authors.
Excited to share STAPLER, a language model to predict TCR – pMHC reactivity that outperforms prior models. And for ML aficionados: Description of a new data leakage problem inherent to a common negative data generation strategy. biorxiv.org/content/10.110… 🧵👇
Congratulations David Baker (@UW, member of #CancerGrandChallenges team MATCHMAKERS), who's won the 2024 Nobel Prize in Chemistry for his pioneering work building new kinds of proteins! 👏 More about MATCHMAKERS, funded by @CR_UK @theNCI @TheMarkFdn 👉 cancergrandchallenges.org/matchmakers
It's not easy to get hold of a newly awarded Nobel Prize laureate! We are happy that chemistry laureate David Baker took our call, as he turned down "100 calls" while he was on the phone with us. Hold tight for our upcoming interview with Baker.
Ton Schumacher is closing #CancerHostTI24 discussing neoantigens and neoadjuvant therapy. With his research group he created technologies to dissect T cell responses in cancer and contributed to the development of adoptive T cell therapies and neoadjuvant cancer immunotherapy.
Researchers from the group of @HaanenJohn and @Schumacher_lab have successfully developed a novel method that enables the identification of T cell receptors at an unprecedented scale ➡️ bit.ly/3Ql6ObG
We’re excited to reveal that Team MATCHMAKERS has been selected by @CancerGrand to receive up to $25m over five years to take on one of cancer’s toughest challenges. Congratulations to Ton Schumacher @schumacher_lab and all the #CancerGrandChallenges teams!
Excited to share STAPLER, a language model to predict TCR – pMHC reactivity that outperforms prior models. And for ML aficionados: Description of a new data leakage problem inherent to a common negative data generation strategy. biorxiv.org/content/10.110… 🧵👇
Follow our cancer immunology colleagues @NKI_nl
Hello world! The Schumacher lab is now also on Twitter!😃🔬
Woohoo 🙌🙌🙌! If you’re into immunology and immunotherapy, then you must know Ton Schumacher! Follow the lab’s new twitter account! @NKI_nl
Hello world! The Schumacher lab is now also on Twitter!😃🔬
Follow the Schumacher lab! (Exciting stuff coming up)
Hello world! The Schumacher lab is now also on Twitter!😃🔬
Impossible immunotherapy responses? It's the gamma delta's bro! Thrilled to see our work on γδ T cells and "impossible" immunotherapy responses of B2M mutant cancers in @Nature 🧵 below 👇👇👇
Identification of patient-specific CD4⁺ and CD8⁺ T cell neoantigens through HLA-unbiased genetic screens go.nature.com/3Ida0mm
Gene function is associated with distinct mRNA – protein levels. We show that mRNA, protein, and mRNA-protein levels are associated with sequence characteristics in human CD8+ T cells. In the lab of @WolkersMonika at @sanquin You can read more here: dx.plos.org/10.1371/journa…
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Who to follow
-
AI for Oncology Lab
@AI4Oncology -
Cassian Yee
@tcellsrus -
Ton Schumacher Lab
@Schumacher_lab -
Dr Chris Thorpe
@drchristhorpe -
NicklectedTropicalDiseases
@NickdeVrij -
David Gfeller
@GfellerD -
Pieter Meysman
@chevaliersf -
Jonas Teuwen
@jonasteuwen -
Jani Huuhtanen
@jhuuhtan -
Benoit Nicolet
@BenNicolet -
Roberta Zappasodi
@RZappasodi -
Poor Man's ab lab
@theamsoon_lab -
Joris van de Haar
@Joris_vd_Haar -
Pengfei Zhang
@Pengfei17365177 -
vincentvB
@BVincentv
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