Michael Wilson
@wilson_mdGenome biologist, SickKids Research Institute
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New article: Authors investigate the age-, sex- and cell-type-specific gene regulation in the hypothalamus across the pubertal transition. "Hypothalamus plays a central role in regulating puberty," they write: bsd.biomedcentral.com/articles/10.11…
Excited to present our new preprint: Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes: biorxiv.org/content/10.110…. TOP2B ChIP to analyse non-coding drivers & mutational processes in 6k cancer genomes +in vivo validation of RMRP locus as a new driver.
Our latest paper is out: "Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways" nature.com/articles/s4146…
Interested in early heart development, regulatory elements, congenital heart disease, or chromatin biology? Come check out our posters from the labs of @iscotthsc and @wilson_md at #izfc2024 🇯🇵🐟 Poster session 2 (Aug 19) # 19, 84 Poster session 3 (Aug 20) # 55 @monis_simon
As the year ends, there’s no better time to reflect on all the incredible work being done by our scientists. 🧑🔬 From novel #glioblastoma research🧠 to potentially diagnosing #cancer earlier, this #SKResearchRoundUp showcases some #SKResearch highlights from 2023! 👇 [1/13]
Wonderful talk by @Esra_JN_Erkut from @iscotthsc ‘s team on her 🤩 research using zebrafish to identify deleterious mutations in noncoding genome that underlie congenital heart disorders. 👏 to our trainees who are driving discoveries @SickKidsNews
Amidst the mountains Gathering of scientists Chromatin abounds #CanEpi23
And that's a wrap on #CanEpi23! Thank you to everyone who attended and all of the sponsors for their continued support of our meeting. We've enjoyed seeing all of the amazing science and wonderful interactions that have taken place over the last 3 days. See you all in 2024!
How can a blood test developed by @OICRGenomics help find #cancer earlier and change the lives of people who inherit a high risk of cancer? ▶️oicr.on.ca/landmark-study… Dr. Trevor Pugh (@PughLab) explains his new landmark study with colleagues @pmcancercentre @UHN @SickKidsNews
Not only a beautiful cover but also a game changing moment to have Mexican Genomics highlighted in the cover of @Nature as it brings the spotlight to Latin America and the Global South towards a more inclusive and locally led research in underrepresented regions of the world 🌎✊
Thrilled that our preprint describing our participation in the “SickKids clinical genomes and transcriptomes” @CAGInews challenge is now out in Research Square! researchsquare.com/article/rs-340…. One of the winning solutions of the challenge! #Transcriptomics #Genomics
This was an exciting CAGI challenge! The problem is hard: give the probability for every gene to be causal for an unsolved rare disease case from omics data. We encourage other labs to participate in future editions. Important tasks + strengthens the team spirit in your lab.
Thrilled that our preprint describing our participation in the “SickKids clinical genomes and transcriptomes” @CAGInews challenge is now out in Research Square! researchsquare.com/article/rs-340…. One of the winning solutions of the challenge! #Transcriptomics #Genomics
Deadline this week! Generous startup pkg ✅ Broad search ✅ Reasearch-focused position ✅ Vibrant and collaborative community ✅ Quality of life ✅
I am thrilled to announce the first 2 of 3 faculty positions we are opening at the Lunenfeld-Tanenbaum Research Institute @SinaiHealth in Toronto, Canada, in Systems, Chemical, Developmental or Molecular Biology, focusing on studying and treating human diseases. 1/5
From UD notice that was sent out. So legends are ok to be in a different font.
Awesome show tonight @TheDanforthMH with @odonovanaoife and @NickelCreek! So nice to get out on a Wednesday. Holding pattern was an amazing encore. youtu.be/ekd56l9JQMI
Very excited to be sharing my project from the labs of @iscotthsc and @wilson_md at #2023SDB! I'll also be presenting my poster on Saturday, July 22nd, 2:00 PM - 4:30 PM #2023SDBEnh 🐟🧬
📣If you are at the 12th European Zebrafish Meeting 2023, don't miss @CaseyMCarlisle 's talk on outflow tract enhancers!🐟🧬 Exciting work led by Casey @iscotthsc and @wilson_md 🗓️Date: Tuesday, July 11th ⏰Time: 10:30 AM - 12:00 PM (Poland time) #EZM2023
Looking forward to @guilbourque's visit and talk today on human pangenome graphs (11AM in MS 2172)! Join us if you can. @uoftmedicine
Double congratulations Erin! It was great to get a preview of this fantastic work in Kansas City last year!
For more…Follow me and the Jimenez lab! I am thrilled to share that I will join the vibrant scientific community of the @JohnsHopkins Dept of Biology this July as an Assistant Professor.
Me too! See you soon.
Congratulations to the @HumanPangenome - in particular @BenedictPaten for his leadership + highlighting @ensembl's role via Fergal Martin in annotation. For the rest of this thread I will explain this technical genomics tour de force using... Shakespeare nature.com/articles/s4158…
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