@sophiejamess_ Profile picture

Sophie James

@sophiejamess_

PhD student looking at bone marrow driven mechanisms of therapy resistance in AML @CRUKCOLcentre @QMBCI @TheCrick

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Sophie James Reposted

We are very pleased to announce that our work on Stearoyl-CoA desaturase (SCD) inhibition in AML has now been published in @LeukemiaJnl Link here rdcu.be/dR0r3 Below link to a tweetorial I wrote when we published the preprint Since then the paper has been updated 1

Preprint alert! biorxiv.org/content/10.110… A very enjoyable work led by @VilmaDembitz perseverance and talent but also made possible by the help provided by a wide range of excellent senior and junior collaborators. A refreshing experience for a young academic! Thread 👇 1/10



Sophie James Reposted

Had a great few days in Berlin speaking at the @ipscconf conference & catching up with fellow @CRUKCOLcentre students. Thanks to the organisers for planning a fun event packed with interactive workshops & amazing keynote talks. @markowetzlab @BergersLab @jacksonlab

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Sophie James Reposted

The first PhD from the lab graduated yesterday! Huge congrats to @AoifeMagee95 for her achievements and hard work. Best of luck for your future challenges! Thanks to all @QMBCI for their support of Aoife work.Special thanks to the examiners @NRodriguesLab and @robertobellell1

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Sophie James Reposted

We would like to thank the 100+ basic #hematology researchers for joining us for #EHAReCon2024. This meeting, focused on molecular vulnerabilities & metabolism in hematological disorders, featured unpublished research & new connections. Stay tuned for #EHAReCon2025.

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Very pleased to get the opportunity to present my research at the CoL Centre paediatric cancer symposium on Thursday!

We heard 5 wonderful talks from City of London Centre students in paediatric cancer @sophiejamess @paologallipoli lab, Amelia Claxton @MayaThanou lab, Dorothy Yang @JNArnoldLab, Sumayyah Imran @sghorashian lab, and Gonzalo Mercado @straathof_karin lab. colcc.ac.uk/training-progr…

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Sophie James Reposted

Job advert alert!!! 👇 We have an exciting project to dissect the role of mannose metabolism in normal/AML stem cells using advanced in vitro and in vivo models. qmul.ac.uk/jobs/vacancies… Perfectly suited for an enthusiastic postdoc with interest in metabolism and in vivo models 1


Sophie James Reposted

In another piece of good news, I am pleased to say that our paper on how to model AML chemotherapy in NBSGW mice is now published @Hemasphere_EHA onlinelibrary.wiley.com/doi/10.1002/he…


Sophie James Reposted

I cannot recommend working in this lab more. Paolo is a great PI and mentor, the lab colleagues are friendly and helpful, Bart's has a wonderful AML/hematology community and I can guarantee the project will be extremely exciting. Apply today!

There are still 2 weeks left to apply for this position in my lab. If you are keen to study AML biology, like metabolism and want to lead a project with huge translational potential then look no further! Always happy to chat informally as well. DM me.



Sophie James Reposted

Delighted to offer a 3 year Post Doctoral position in collaboration with @scienceadvocacy investigating modified cytokine function in HSCs and hematopoiesis funded by @CRUKresearch Please get in touch if you're interested in joining us @CBR_UoY @YBRI_UoY

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Sophie James Reposted

Are you an early-stage #scientist or #clinician with an interest in paediatric and young adult #nonHodgkin #lymphoma? Do you want to meet likeminded people working together to improve outcomes for patients suffering with #NHL? If so, we have the perfect opportunity for you! #1


Very happy that this is out today 🥳🥳🥳

Now online! Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis dlvr.it/Sv9s81



Sophie James Reposted

Delighted to share our newest publication, now online @CellCellPress! The result of a great collaboration with colleagues @StanfordMed @PiehlerLab and from @UniOfYork @Bill_G_Grey and @sophiejamess_ and others not on Twitter. Thanks to @CRUKresearch for funding. Enjoy!

Now online! Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis dlvr.it/Sv9s81



Sophie James Reposted

Preprint alert! biorxiv.org/content/10.110… A very enjoyable work led by @VilmaDembitz perseverance and talent but also made possible by the help provided by a wide range of excellent senior and junior collaborators. A refreshing experience for a young academic! Thread 👇 1/10


Sophie James Reposted

We have an exciting postdoctoral training opportunity combining intravital microscopy and transcriptomics to study leukaemia resistance to treatments at Imperial College + Crick Institute.  If you are interested/know anyone who may be, please get in touch/fwd this message


Sophie James Reposted

Very proud of our @CRUKresearch funded postdoc Zahra Masoumi for presenting our latest work at #EHA2023. Watch out for the full story, released into the wild soon! Congrats also to other @BiologyatYork co-authors @Bill_G_Grey @sophiejamess_ Julie Tucker and Lucie Moss

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Sophie James Reposted

It is a great pleasure to announce that the first research paper from the lab is now published in @NatureComms Links for PDF rdcu.be/c9T03 and on line version nature.com/articles/s4146… This is a milestone for the lab and a special thanks goes to @WoodleyDr who led it 1/n


Sophie James Reposted

The lab was out in the pub last night....watch this space as news coming....😎 @WoodleyDr @AoifeMagee95 @sophiejamess_ @VilmaDembitz on line from Croatia

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Sophie James Reposted

We are hiring! 36 months postdoc position available in my lab to characterise metabolic rewiring in AML funded by @Barts_Charity Please circulate/retweet and if interested contact me. Closing date Feb 24th qmul.ac.uk/jobs/vacancies…


A brilliant week!

Fantastic week of science and opportunity to showcase our work internationally thanks to poster and oral from postdocs in the lab. All helped by Sicilian weather and food #EHARecon

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Sophie James Reposted

Are you interested in doing a PhD at the CoL Centre? Applications are now open for Clinical Research Training Fellowships. Find out about the projects available and details on how to apply: colcc.ac.uk/clinical-resea…


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