Sara Federici
@sary82Microbiologist, #postdoc @Elinav_Lab @WeizmannScience #microbiome. Trusting the process 🧬
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It's out! Our paper on phage therapy against K. pneumoniae, this wouldn't have been possible without Sharon Kredo-Russo, @rvaldesmas, Denise Kviatcovsky, several tremendously excellent partners, and of course last but not least, @EranElinav!! @Elinav_Lab
Proud to share our new work @CellCellPress We identified and experimentally validated #microbiome strains contributing to IBD flareups across geography (4 countries), and developed a first-of-its kind combination phage therapy cell.com/cell/fulltext/…
BREAKING: This year's #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun. The pair have been recognised "for the discovery of microRNA and its role in post-transcriptional gene regulation." Stay tuned for more from @nature
NEW publication out in @NatureMicrobiol!🥳 The conidial surfaceome (surface proteins) of #Aspergillus fumigatus contains unique proteins absent in non-pathogenic relatives. KOs revealed 33 genes affect #pathogenesis and related traits, indicating the surfaceome impacts virulence
Congrats for this fantastic achievement @IvanBassi3 @KarinaYaniv @L_GutiMiranda @RuizdeAlmodovar well deserved!! 👏🏻 🥳
Our latest work on the NeuroVascular Unit is out! New insights into neuronal vs. glia differentiation, Notch3 regulation, BBB formation and more! All spearheaded by the one and only @IvanBassi3 in close collaboration with @RuizdeAlmodovar! 1/5 nature.com/articles/s4146…
Ever wondered how the microbiome controls antigen presentation in immunity? Check out our review on the latest developments in the field @Elinav_Lab @gayatree620 @asokan_sahana_ & Yiming He sciencedirect.com/science/articl…
A new retron-based method from the innovative @seth_shipman lab now allows making multiple mutations in a phage genome in a single, easy process - from point mutations to small insertions and deletions Read the overview by @IlyaOsterman nature.com/articles/s4158…
Multiplexed editing of phage genomes using retrons, now published at @NatureBiotech with lots of new bells and whistles. @ChloeFishman @katecrawdaddy @BhattaraiKline @Darshini_Poola @thekarenzhang @alex_gonzadel @matromont nature.com/articles/s4158…
Erica Birkholz (@UCSanDiego) and colleagues investigated the role of a homing endonuclease in viral competition, showing that it interferes with the replication of competing #phages, providing a fitness advantage. buff.ly/4d88Uou
I am excited to share the first story from my lab at @WeizmannScience, led by the amazing @AnnaRudnitsky If you're interested in oral tolerance and how the host handles 'Trojan horse' immune attacks by seemingly harmless entities, this is for you. twtr.to/s70NB /1
🚨Are you interested in exploring the fascinating world of RNA phages? We are recruiting a PhD student and a postdoc to join us @Helmholtz_HIRI! Please spread the word! More info: helmholtz-hiri.de/en/jobs-talent…
For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s4158…
Home made pizza, Italian style 🇮🇹🍕 to say good bye to the one and only @IvanBassi3! We will miss you very much! @yaniv_lab
Celebrating @FadiSheban 🎉 Congratulations for your PhD defence to better define the regulatory circuits of tumor associated macrophages and apply this knowledge for novel immunotherapy 🏆
The 12 most creative ads you'll ever see: ✋🏿1. Sam - looking for a designer
The best person I know (successful, smart, and with a genuinely good heart) is recruiting new team members. Highly (!!!) recommended 🌟👍👨⚕️🐊
We are looking for exceptional MSc and PhD students! 👩🔬🧪🔬🧑🔬🧫💩 If you're interested in exploring the interface between gastrointestinal tract immunity and the microbiota in various diseases and combining basic science with NGS in the best environment possible - send me a DM
Nicole Schmid (@jlugiessen) and colleagues have described the interactions between a Shewanella inovirus and an autonomously replicating plasmid, which hijacks the #phage infection process to preferentially package itself. buff.ly/3Ufr0hq
MicrobiotaProcess: A comprehensive R package for deep mining microbiome hubs.li/Q02rNZnR0 Outstanding research from @The_InnovationJ — Impact Factor 33.1
OUT NOW in @Nature: DNA glycosylases provide antiviral defence in prokaryotes @amer_hossai1 @ChristianF_Baca @PhoebeARice @MarraffiniLab nature.com/articles/s4158…
Pieter-Jan Haas’ group at @UMCUtrecht is seeking a #postdoc to identify the most relevant defense and counter defense mechanisms in clinical strains and #phages of the bacterial pathogen P. aeruginosa. buff.ly/3U441FR
Infant gut microbes have their own circadian rhythm. Read more in @cellhostmicrobe: cell.com/cell-host-micr… @TU_Muenchen Dirk Haller
Happy to share the first @yaniv_lab entry into the fascinating world of lymphatic malformations! @IvanBassi3 took a mutation identified by our collaborators all the way to a zebrafish screen and found surprising results! More details soon!! biorxiv.org/content/10.110…
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Lena Schorr
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Eran Elinav
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