Noémie Lefrancq
@noemielefrancqPhylogenetics 🧬 & infectious disease dynamics 🦠 ETH fellow at @ETH_BSSE PhD from @Cambridge_Uni. Also on Mastodon: @[email protected]
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Our article on Global spatial dynamics and vaccine-induced fitness changes of Bordetella #pertussis is out in @ScienceTM! Using #phylogenetic models, we investigate #pertussis spatial #spread, and #fitness shifts in response to vaccine changes. 🧵1/10 science.org/doi/10.1126/sc…
Thrilled to have received this award, thank you @GenSocUK! Many thanks to @hsalje @JulianParkhill, @sylvainbrisse and the amazing research groups without whom the work wouldn't have been possible! @PDUCambridge @PathGenEvoCam
A big congratulations to @noemielefrancq on being awarded the Sir Kenneth Mather Memorial Prize🏅 for their exceptional PhD thesis on global dynamics of the bacterium behind whooping cough, using genomes from throughout Europe and the world! genetics.org.uk/medals-and-pri…
Really excited to share that our study is finally published in @Nature ! Longer post to follow but thanks so much to all of my co-authors, supervisors, the GPS consortium, and reviewers. @noemielefrancq @hsalje @StephenBentley5 @pneumowatch nature.com/articles/s4158…
DECODING GENOMES - from sequences to phylodynamics: We are proud to present our book on how to analyse genomic sequences with an evolutionary perspective. See decodinggenomes.org for a free pdf, Amazon links for print orders, and further information. Great team effort 1/2
Our analysis on the genetic diversity of #nipah virus is out in JID! We analyzed 257 geocoded #genetic sequences collected between 1999 and 2020 in South and Southeast Asia. academic.oup.com/jid/advance-ar…
Finally made it! 🎉 Thanks to @nrt_thomson & @nunorfaria for examining my thesis and great discussions during the viva! Big thanks to @hsalje and @JulianParkhill and the great @PDUCambridge and @PathGenEvoCam teams for making these years amazing! 🦠
Congratulations to the amazing DR Noémie Lefrancq who passed her viva with no corrections. The work presents an exciting way to quantify evolving pathogen fitness from sequences that is relevant across diseases. Thanks to Nuno Faria and Nick Thomson for being great examiners.
New work led by Wei Wang characterizing the dynamics of measles immunity in infant & child cohorts in China @PDUCambridge nature.com/articles/s4156…
We are hiring a postdoctoral researcher in bacterial genomics to study commensal E. coli epidemiology and evolution in an ERC-funded project. Please retweet!
Postdoc (Paris, France) Understanding the evolutionary epidemiology of commensal Escherichia coli with bacterial genomic data with @FrancoisJB at @CirbCdf @IAME_Center @CNRSbiologie More details: iddjobs.org/jobs/understan…
Our paper on the role of antigenic space in determining dengue disease risk is out as a cover article @ScienceTM science.org/doi/10.1126/sc…
A new paper that combines antigenic analysis of #dengue with 2 decades of hospital data in Thailand teases apart how different combinations of serotypes shape the risk of severe secondary infections in children. @hsalje @datcummings @fdlwang @GeneticsCam scim.ag/6Km
🚨 Clockor2 is now out in Systematic Biology! 🚨 We have added some helpful new features including dark mode and better download options A massive thank you to my collaborators Andrew Rambaut, @sebduchene, and @wytamma! @systbiol (1/4)
🚨 Want to fit a molecular clock, or 2? 🚨 👉 Try clockor2.github.io - a client side tool for fitting global and local clocks with root-to-tip regression. Developed in collaboration with @wytamma, @arambaut, and @sebduchene (rb.gy/dro6j)
Two weeks ago I gave a plenary at #Epidemics9 conference on privilege in academic epidemic modelling. You can read an overview (shorturl.at/cinDX) and watch a fresh recording if you have 45mins to spare (youtu.be/Jcr2dbiqLY4). Enjoy and send feedback please!
Privilege in academic modelling careers: @dr_anne_cori 's thought provoking plenary session at #Epidemics9 conference in Bologna, Italy👇 🧵1/2 imperial.ac.uk/news/249996/pr…
Excited to present our poster on the genetic diversity of Nipah virus later today at #Epidemics9 - Come say hi at poster P2.167! 🦇 @PDGCambridge
What do we need to do to get genomic surveillance working for AMR? 🦠🧬💊Our series in @LancetMicrobe reports 9 recommendations from the @SEDRICThinkTank working group. Check out the papers: thelancet.com/series/amr-gen… and the 🧵below for more 1/13
New estimates suggest that mpox has been circulating in humans since at least 2016. science.org/doi/full/10.11…
Delighted to have been awarded the Johnstone and Florence Stoney Award 🎉🎉 for my PhD work on The global dynamics of Bordetella pertussis and implications for control. Thanks to the @BFWGraduates, my supervisors and collaborators for the support! bfwg.org.uk/bfwg2/bfwg-aca…
I am recruiting a PhD to work with me to understand why some pneumococcal lineages undergo more recombinations? You will learn molecular microbiology, bioinformatics & programming analyse genome data. In collaboration with @StephenBentley5 @EpicFeil_ findaphd.com/phds/project/e…
It's recruitment time @GeneticsCam 🦠🧫👏🥳 !!! 3 year computational postdoc doing cool Shigella AMR genomics with me and other fun people. Read more here jobs.cam.ac.uk/job/43349/ Would appreciate RTs!
Our article on viral genetic clustering and transmission dynamics of the 2022 #mpox outbreak in Portugal is out @NatureMedicine!! We combined #genomic and #epidemiological data to better understand early viral spread and transmission dynamics. nature.com/articles/s4159… 🧵(1/7)
Hey molecular epidemiologists! If you ever asked yourself, “is it the same strain?”, this paper might be for you. Our sameStrain modelling framework created with @LullaOpatowski and Audrey Duval is published today in @LancetMicrobe doi.org/10.1016/S2666-…
Beautiful early morning in Cambridge ❄️ Credit photo: @BelmanSophie
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