Mu Yang, Ph.D.
@mumumouseBehavioral Neuroscientist https://t.co/qWCSlAeiY4
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As a field, we neuroscientists working on Alzheimer’s disease and related diseases need to have a candid dialogue about research integrity. Important reporting from @cpiller science.org/content/articl…
Spending time with the two amazing physics professors (retired, Perking University) who raised me to value scientific integrity above all else. Hi from Beijing.
Amazing teamwork!
My latest investigation for @newsfromscience: Star neuroscientist Berislav Zlokovic of @KECKSchool_USC implicated in possible misconduct involving apparent data doctoring going back 25+ years. Includes science behind a stroke drug in major human trials 1/5 science.org/content/articl…
AI found the left part yesterday. I saw the right part and just remembered that I saw it yesterday hehe
Update: I found some sort of phenserine in 4 studies. Despite differences in names, they (mostly) all share the AChE IC50 value of 24 +/- 6.0 and BChE IC50 value of 1300+/-85. @ArbitraryEffect @StephenABoydPh1 @LogarithmicDis @MicrobiomDigest
Can I have some chemistry folks to take a look? Main question is: are the same numbers belong to the same compounds or their derivatives/metabolites/analogues?
This is of concern indeed. Here is another way of marking it:
I’m honored to be a winner of the National Academies/Schmidt Award for Excellence in Science Communications, for stories highlighting signs of misconduct in Alzheimer’s research thanks to courageous whistleblowers like @schrag_matthew #sciencejournalism @scicommexcellence
Congratulations to @cpiller, winner of an Eric and Wendy Schmidt Award for Excellence in Science Communications in the Science Journalist: Freelancer category. @SciCommAwards brnw.ch/12s1j 🏆 Here’s a look at his winning stories. (THREAD 🧵)
The two tables are from two papers. The same/almost-same numbers don't seem to belong to the same compounds? Both UC Chapel Hill studies.
Another example of different populations having very similar curves. pubmed 34944711
The similarity between data in pink boxes are puzzling. From what I understand, one population ceased to exist and the other kept on living? pubmed 31906036
Data in pink boxes only have minor differences, which is unexpected given that they are said to represent different populations (with different Ns). PMID 31906036
The data in pink boxes look very similar. Ns are quite different. PMID: 32235551
My full name today is Daenerys Targarybik, First of Her Name, Queen of ImageForensics, Khaleesi of the Great Twitter Sea, Protector of Science, Lady Regent of Microbiology, Breaker of Misconduct, and Mother of Turtles. Just gave a talk@PennMedicine like this! #HappyHalloween
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