@mirimiam Profile picture

Manuel Irimia

@mirimiam

ICREA Evolutionary Biologist working on transcriptomics of development and evolution at @UPFbiomed and @CRGenomica. Coordinator of the @EvoMG_Bcn Joint Program.

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Pinned

New release of annotations in @VastDB (v11). With this release we cover all the previous studies experimentally investigating the functions of AS events we were aware of, with a total of 5542 entries (EventID-PubmedID pairs). @CRGenomica

We have released a new batch of functional annotations (v11): 600 entries from previous publications investigating the function of AS events. This makes a total of 3637 entries directly from publications, 397 from CRISPR screens and 1511 from experimentally validated ELMs.

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Manuel Irimia Reposted

💥 Last day to register! Inaugural Symposium of the @@EvoMG_Bcn Great line-up of speakers covering a wide range of topics, all of which share an evolutionary approach to understanding and/or tackling human disease, More info and registration : tinyurl.com/EvoMGSymp

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Manuel Irimia Reposted

Great collaboration with @lrdesviat and @AndresenBrage to find ways to modulate inclusion of a microexon (CPEB4 exon 4) involved in autism! @sarapico7 @mirimiam @GeschwindLab @ParrasAlbert @RMendezLab @SENC_ @CBM_CSIC_UAM @CIBER_ISCIII


Manuel Irimia Reposted

Logrado el primer mapa del espliceosoma, un talón de Aquiles del cáncer. El plano de esta laberíntica maquinaria celular, la más compleja en el ser humano, abre una nueva vía para diseñar tratamientos contra multitud de enfermedades: elpais.com/ciencia/2024-1…


Manuel Irimia Reposted

Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

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Manuel Irimia Reposted

How does evolution result in cool structures like a bat wing? With single-cell, genomics & transgenics we show how a whole evolutionarily conserved gene program is repurposed in a different anatomical position to develop 🦇 wings! biorxiv.org/content/10.110… A 🧵 on our journey:

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Manuel Irimia Reposted

LAST DAYS TO APPLY❗ Join us for the Inaugural Symposium of the Evolutionary Medical Genomics Program (@EvoMG_Bcn) from Nov 20-22 at @the_prbb in #Barcelona! ⚡ Discover how evolutionary insights can help tackle human disease. 🫀 📩 Register by Oct 30:  tinyurl.com/EvoMGSymp

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Manuel Irimia Reposted

📣 If you are interested in #RNA #Splicing using long or short #RNASeq check out our recent paper on combining and contrasting short and long reads for this genome.cshlp.org/content/early/… - we think there are some important lessons for where/how you invest time/💰 🧐and...


Manuel Irimia Reposted

We have several open positions in our lab. If you are passionate about proteins and AI, come join us at an excellent location at @CRGenomica @the_prbb ! aiproteindesign.com/jointhelab


Manuel Irimia Reposted

We are excited to announce the 2nd edition of our theoretical and practical course “New Technologies for Developmental Evolutionary Biology Studies” : sites.google.com/view/evodevo20… 16th-19th December 2024 at Universidad Autónoma de Madrid, Spain Application deadline: 25th October


Manuel Irimia Reposted

🚨🚨🚨 Very excited to share our new preprint on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4: biorxiv.org/cgi/content/sh… Work led by @SoBonnal, with Simon Bajew & @rmartinezcorral @UPFbiomed, @CRGenomica @ERC_Research Short teaser👇1/7


Manuel Irimia Reposted

🚨PhD position in the lab in a collaborative project with @bitbio 📩 interested? get in touch for further info 🔁Please RT and share with fitting candidates

FUNDED PHD OPPORTUNITY: Defining the rate limiting steps of differentiation tempo through deterministic forward programming with Dr Teresa Rayon Apply by 24th November Find out more: babraham.ac.uk/work-and-study… #PhD #PhDVacancies #PhDStudents #PhDProjects

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Manuel Irimia Reposted

We are launching a crowdfunding campaign for LUMIRIS!!(Mon 23rd) @CapitalCellNet Join our informative webinar Thurs 26th 19:00 (CEST). Book a spot at info@lumiris.tech capitalcell.com/campaign/lumir…


Manuel Irimia Reposted

Join us for the Inaugural Symposium of the Evolutionary Medical Genomics Program (@EvoMG_Bcn) from Nov 20-22 at @the_prbb in #Barcelona! ⚡ Discover how evolutionary insights can help tackle human disease. 🫀 📩 Register by Oct 30:  tinyurl.com/EvoMGSymp

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Manuel Irimia Reposted

Announcing our recent preprint on the cis-regulatory landscape shaping microexon splicing and its regulation by SRRM3/4! You can read the teaser by @mirimiam and delve into the detailed findings here: biorxiv.org/cgi/content/sh…

🚨🚨🚨 Very excited to share our new preprint on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4: biorxiv.org/cgi/content/sh… Work led by @SoBonnal, with Simon Bajew & @rmartinezcorral @UPFbiomed, @CRGenomica @ERC_Research Short teaser👇1/7



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