Kristin Sticco, DO MS
@ksticcoMDMom, wife and BC hematopathologist AND transfusion medicine physician. Tweets are not medical advice, opinion only.
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Illustration of the floral variant of follicular lymphoma➡️ 🩸Rare distinct morphologic entity 🩸Can be seen in all grades of FL 🩸Most importantly: Can mimic progressive transformation of germinal center (PTGC) 🩸Which may lead to underdiganosis as a reactive, rather than a…
In fact: if you see MDS with increased blasts and increased ring sideroblasts.. there's a pretty good chance you're dealing with TP53 mutated MDS as shown nicely in this study in @LeukemiaJnl nature.com/articles/s4137… 8/
I am delighted to announce that the Journal of Hematopathology @JHemepath has been indexed in MEDLINE/Pubmed! Please consider our journal for all your hematopathology-associated manuscripts! Tell your friends!
Whole genome view of a bone marrow aspirate … 1. 6% blasts on differential 2. Myeloid phenotype 3. Multilineage dysplasia , 24% ring sideroblasts 4. One pathogenic mutation (will reveal later) What’s the most likely @WHO 5th diagnosis? Poll 👇🏼
45M presented with diarrhea. AP/CP boards questions. #pathboards This is Giardia infection. Described as falling leaves, or kite and pear shaped trophozoites along the intestinal brush border. @ParasiteGal @ksticcoMD
Patient with history of myelomonocytic leukemia post treatment, below is a follow up flow cytometry analysis of his peripheral blood months later, showing an expanded population in the CD45-dim gate (aka "blast-gate") #hemepath #PathTwitter #leusm #MedEd #MedTwitter #MedX…
Viral infections may show striking T-cell atypia; which in the absence of adequate clinical history, may be worked-up for T-cell lymphoma Below are pictures from a peripheral blood smear of a patient with an acute viral illness & remarkable lymphocytic atypia #hemepath #lymsm
Check out Haematologica now! A whole series of reviews on peripheral T-cell lymphoma. A fascinating and understudied group of disorders badly in new of new and effective therapies. @MJAhearne @CwynKate haematologica.org/article/view/h…
Not only can the eosinophil-rich variant of nodal marginal zone lymphoma mimic angioimmunoblastic T-cell lymphoma (AITL), this is true the other way around too: AITL, particularly the EBV-NEGATIVE ones with a MONOTYPIC plasma cell population, can show striking morphologic…
An underrecognized variant of nodal marginal zone lymphoma (NMZL) is the "eosinophil-rich variant", which is a unique subset not mentioned/emphasized by the current WHO/ICC A knowledge of this variant of NMZL can prevent it from being misdiagnosed as PTCL (particularly AITL)…
What is the risk of developing an inhibitor to FVIII/FIX in previously untreated patients w/ severe #hemophilia according to different concentrates? In this #RPTHOriginalarticle the authors report data from 1392 PUPs @ProfMakris @flora_peyvandi Read➡️ rpthjournal.org/article/S2475-…
Make sure to attend our #AABBjc on Dec. 5-6! I will be moderating with @TeamCaptainJohn! We will discuss the guidelines for RBC transfusion. This is not only for our #TransfusionMedicine folks but also interesting discussion for all our #MedX community! See you all there!
SAVE THE DATE! 📅 The AABB Virtual Journal Club will meet Dec. 5-6 to discuss the 2023 AABB international guidelines for red blood cell transfusion, which were published in October in @JAMA_current Sign up for updates: bit.ly/3YAsZNW #AABBjc
Now this is cool #VEXAS vs #CML 🤺 #hemepath #MPNSM I’m always fascinated by the war of clones.. even though the winners and losers are often too predictable. shorturl.at/AHLR4 @BloodAdvances
Stage III Hematogones can express CD5, and this may cause overinterpretation as residual CD5+ B-cell lymphoma. Let's go through 2 examples below that nicely illustrate this⬇️ @ICCS_Education @saada_vsaada #hemepath #Xpath #PathTwitter #MedTwitter #surgpath #lymsm
Have you had a pediatric B-ALL with very mature features previously, that made you question whether you are dealing with a B-cell lymphoma instead? Below is a similar case: Starting with CD38 expression: It is not as "dim" as you would expect it to be in B-ALL #Hemepath #Leusm
Rosai Dorfman vs. Erdheim Chester… while clinically very different.. histopathology can overlap (both histiocytic, but many morphological clues to ddx) #histiocytosis Here is a nice visual summary on how to distinugish these two, from Dr @garces at #hemepathMDA #hemepath
The life of a hematopathologist is full of uncertainty….. 🤷🏻♀️ So you know all there is to know about CCUS …. But did you know about TCUS?? #SH23 #hemepath #lymsm
Any updates in this algorithm? @sanamloghavi @KMirza #hemepath Mayo Clin Proc. 2010;85(2):158:164
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