kalialabs
@kalialabsDiscovering a Cure for Parkinson's Disease and Movement Disorders - molecular mechanisms/novel therapies/neuromodulation. Drs. Lorraine & Suneil Kalia
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@MDJ_Journal
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@kalialabs previously found that excessive alpha-synuclein causes proteosome dysfunction prior to neurodegeneration. Newly minted PhD - Dr Hui - and the team now discovered that these early events also include alterations in mitophagy: tinyurl.com/5n76dxvv
Adaptive/closed-loop #DBS is a fascinating new tool which will likely expand the current list of indications, beyond #Parkinson We used it to understand #orthostatic #tremor during day-to-day conditions but also to stimulate on demand, with better results compared to classic DBS
There is much we can learn from each other. Read the ideas on DMT discovery that came from @UofTNeurology bringing experts in #Parkinsons and #multiplesclerosis together in #Toronto (published with @SpringerNature in @NatRevNeurol) rdcu.be/dWf2U
Explore how #LEDD in #Parkinson's varies globally! 🌍 Experience of two continents spreading six countries. including impact of new Levodopa formulations post-surgery, discover the latest insights on personalized treatment approaches. onlinelibrary.wiley.com/share/author/B… @MichaelOkun
Further proof that #gait is lateralized to the right deep brain, important for programming Specular sweet/sour maps: no results if flipping one hemisphere onto the other! to be kept in mind when you read about studies doing so to increase the sample size doi.org/10.1002/mdc3.1…
Read the latest issue of The Krembil to learn about our recent research advancements, Krembil Research Day 2024, the inaugural Neuronto Research Symposium and a new Krembil team member! bit.ly/3W6IWdG @KBI_UHN @SchroederInst @DKJEI_UHN
New paper from @kalialabs et al finds "high frequency electrical stimulation limits the accumulation of (#Parkinsons-associated) mutant A53T α-Syn & its derangements on cellular pathways involved in the clearance of misfolded proteins & damaged organelles" nature.com/articles/s4159…
Huge congratulations to #TBEP investigators, Profs. @craigsimmons11 and Hai-Ling Margaret Cheng, and their co-investigators, Drs. Phyllis Billia and Lorraine Kalia (@kalialabs) on being awarded Joint EMHSeed funding. engineering.utoronto.ca/2024-2026-join…
Great to catch up with exceptional colleagues and friends at #ASSFN2024 in Nashville. Here with Drs. Adrian Laxton and Suneil Kalia (@kalialabs), for our co-residents reunion! @UofTNeuroSurge @ASSFNeurosurg
#KBIOurPurpose - To decode molecular mechanisms, to discover novel treatments, and to develop innovative applications of neuromodulation to conquer #Parkinson
If art were a drug... @PritiGros Blanca Spee @basbloem @kalialabs provide a qualitative review of art-based interventions for individuals with #Parkinsons, covering music, dance, drama, visual arts, & creative writing; Adaptability to individuals’ needs content.iospress.com/articles/journ…
What do you tell people w/ Parkinson's about cannabis? Nice piece in @journal_PD by Maria Eliza Thomaz de Freitasa and Susan Helen Fox in Canada have a great new piece on this topic. Here is what they tell them. 8 points: 1. There is a lack of evidence-based data on the…
#N2BL @mpc_utoronto student @laurakondr wins🥇(1st place) at 50th Surgery Gallie Day for her research exploring a model of Parkinson’s using electrophysiology. Laura is co-supervised by three @CRANIA_Toronto scientists: @kalialabs @lukamneuro @DrValiante Congratulations Laura 👏🏽!
"Pioneering technology at @UHN gives Parkinson’s patient 2nd chance at music career." Thank you @SusanHayGlobal @globalnewsto for covering this amazing story featuring @DrAlfonsoFasano & Fabio Dwyer. Link to video: bit.ly/4dofUhM
EP 4 of @KBI_UHN's #YourComplexBrain #podcast features Dr. Lorraine Kalia (@Kalialabs) discussing the science-backed benefits of exercise for those living with #Parkinson’s, and Steve Iseman's journey to better health through cycling! Listen & subscribe: bit.ly/3WgAWsr
Can stress function as the straw that breaks the camel's back and trigger Parkinson's? Are sudden onset disorders always functional? van der Heide, Helmich and colleagues present two cases and discuss the possibilities and considerations in a new paper @journal_PD Key Points: -…
“Is Parkinson’s Becoming a Pandemic?” Watch this fascinating interview with @KBI_UHN’s Dr. Lorraine Kalia (@kalialabs) on TVO’s @theagenda, hosted by the always curious @spaikin, and produced by the super talented @preetibhuyan Link to full interview -> bit.ly/3UdRwGB
Escalating rates of Parkinson’s Disease have led some researchers to warn that it is becoming a pandemic. @spaikin speaks to neurologist Dr. Lorraine Kalia (@kalialabs @UHN @KBI_UHN) about her research, tonight at 8/11pm | Producer: @PreetiBhuyan
🎉Excited to share our latest research published @NatureComms We study how STN-DBS engages the subcortical circuitry to produce therapeutic relief and how this recruitment is reflected in #ERNA. -> link to publication: rdcu.be/dEsWu -> thread 🧵👇
Drs. Eun Jung Lee, David Aguirre-Padilla, Lorraine Kalia, and Suneil Kalia (@kalialabs) @KBI_UHN have uncovered potential disease-modifying effects of deep brain stimulation—offering hope to people living with #ParkinsonsDisease. > uhnresearch.ca/news/breakthro…; doi.org/10.1016/j.brs.…
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Who to follow
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Movement Disorders Journal
@MDJ_Journal -
Alfonso Fasano
@DrAlfonsoFasano -
DBS Think Tank
@DBSThinkTank -
Krembil Brain Institute
@KBI_UHN -
Antonio Strafella
@APStrafella -
Alexandra Boogers
@DrABoogers -
CRANIA
@CRANIA_Toronto -
Sarah Lidstone, MD PhD
@SarahLidstone -
Suvorit Bhowmick
@Suvorit_B -
Integrated Movement Disorders Program (IMDP)
@IntegratedMove -
Husain Shakil
@HusainShakil2 -
Jacky Ganguly
@JackyGanguly -
Donald Weaver
@DrDonWeaver -
SusanFox
@DrSusanHFox -
Francesca Morgante
@franci_morgante
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