Jessica Andreani
@jessica_compbioResearcher in comp bio Prot-prot & prot-RNA interactions, struct & evol Also mum Personal account @[email protected] @jessicaandreani.bsky.social
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New preprint 🚨 We investigated how protein-RNA interface structure evolves by thoroughly analyzing the conservation of contacts among 2022 pairs of homologous interfaces. Work with Ikram Mahmoudi, Chloé Quignot, Carla Martins @I2BCParisSaclay @CEA_Joliot
Structural comparison of protein-RNA homologous interfaces reveals widespread overall conservation contrasted with versatility in ... biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
The Evo 1 paper is now published!
A new Science study presents “Evo”—a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo’s ability to predict, generate, and engineer entire genomic sequences could change the…
A couple years ago I tried to get structural biology people to migrate to 🦋 by handing out invites which were in short supply. It worked for a bit but there wasn't much engagement there. Everything has changed in the last week. So please join us there.
New GPU-based MMseqs2: 20x faster searches on a single L40S (approx. as fast as a RTX 4090) vs. a 128-core CPU. This work enables to set up a very cost-efficient ColabFold MSA GPU server. 🧵 📄biorxiv.org/content/10.110… 💾mmseqs.com 🗞️ developer.nvidia.com/blog/boost-alp…
The Institute for Integrative Biology of the Cell @I2BCParisSaclay is seeking to recruit new group leaders in cell biology @UnivParisSaclay @CNRSbiologie @CEAParisSaclay The application dealine is February 28, 2025
Today we report in @NatureBiotech a system for the laboratory evolution of engineered virus-like particles (eVLPs) that enables the discovery of eVLP variants with desired properties, including improved production and delivery potency. 1/13 PDF: drive.google.com/file/d/1E6Nr86…
Protenix - Yet another reproduction of AF3 github.com/bytedance/Prot…
Protenix: Protein + X | ByteDance - A trainable PyTorch reproduction of AlphaFold 3 GitHub: github.com/bytedance/Prot…
Remember Golden Gate Claude? @etowah0 and I have been working on applying the same mechanistic interpretability techniques to protein language models. We found lots of features and they’re... pretty weird? 🧵
Hi TED! 👋 Out now in @ScienceMagazine , we are finally ready to make our classification of all domains in AFDB v4 available to all! A joint effort of @CATH_Gene3D and the Jones group (@psipred), here's a link to the article science.org/doi/10.1126/sc… 1/5 🧵⤵️
This could be a good time to remind those that may have not seen it before, that the @reactome database at @emblebi also has a library of open access icons reactome.org/icon-lib
🚨 New preprint alert! 🚨 We're excited to share our latest work: "Towards a complete phage tail fiber structure atlas" 🦠🔬 of first author @VKleinSousa We developed #RBPseg for segmenting and merging phage tail fibers using structural prediction tools. tinyurl.com/58cn2ew7
This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) bioart.niaid.nih.gov
AI has dreamt up a blizzard of new proteins. Do any of them actually work? go.nature.com/48oAeNX
Much of the success of breakthroughs, such as AlphaFold, is thanks to a database of protein structures dreamed up in the 1960s by Helen Berman go.nature.com/4hp4UCP
You still have a couple of weeks to submit an abstract for our next #LEGO meeting day in Paris! gt-lego.cnrs.fr/animation/lego…
DENSE is out! Mine your genome and highlight its de novo genes :D
De Novo Emerged Gene Search in Eukaryotes with DENSE | @scoopit sco.lt/8RJ9yS @anne__lopes @GenomeBiolEvol #denovogenes
Join us in Paris on April 8th-10th for the 2025 Symposium on the Immune System of Bacteria 🥖🍷🦠🧬. Excited to welcome these amazing speakers at @institutpasteur . Registration will open beginning of November. Abstract deadline February 28. Stay tuned.
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Who to follow
-
I2BC Paris-Saclay
@I2BCParisSaclay -
Alessandra Carbone
@acarbone16 -
Noelia Ferruz
@ferruz_noelia -
Elodie Laine
@LaineElodie -
Nadège Guiglielmoni
@NGuiglielmoni -
matthieu Chavent
@Matth_Chavent -
Sergei Grudinin
@grudinin -
Alexandre Bonvin - also on Bluesky
@amjjbonvin -
Nathalie Reuter
@reuter_nathalie -
Sarahi L. Garcia
@sarilog -
Thibault Tubiana
@ttubiana -
Ora Furman Lab 🎗
@FurmanLab -
Gianni De Fabritiis
@gdefabritiis -
Roland Dunbrack 🏳️🌈 @rolanddunbrack.bsky.social
@RolandDunbrack -
Arne Elofsson @arneelof.bsky.social
@arneelof
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