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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦

@jaromir_mikes

Flow cytometry, cell sorting, sample processing automation, blood storage and processing, @scilifelab, @karolinskainst, @cytodelics AB company co-founder

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

It been 10 days since Rwanda's #Marburg outbreak, 12 deaths and still no word from president Kagame @PaulKagame - Are these dead doctors and their families not worthy the honor?!

5 days of complete silence from President Kagame @UrugwiroVillage about Marburg outbreak in Rwanda, already one of the biggest on record with 9 dead. @PaulKagame Isn’t this a time to rally behind frontline health care workers. Imagine if the dead were military?! @PressSecRwanda?



Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Two simple parameters to understand if Rwanda is able to contain #marburg outbreak or not. @nsanzimanasabin, 1) how many of the new cases are from known transmission chains? 2) how long are the symptom-to-isolation intervals now?

How can we gauge if the #Marburg outbreak is getting under control? In 2018, @sri_srikrishna & I @TheLancet proposed 2 indicators we should regularly track to know how well an outbreak is being controlled thelancet.com/journals/lance…

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Another excellent example that we are in the era of scRNA-dseq (doublets sequencing) : A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes... biorxiv.org/content/10.110…


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Working to understand your immune system as a system #SystemsImmunology #COVID19 #LongCOVID #Pediatrics : news.ki.se/petter-brodin-…


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Great job dr @PaulKMiddleton !

🥂 Congratulations to Dr @PaulKMiddleton on passing his PhD viva! 🥂 Thanks to @MarkThursz for co-supervising, and to Edmund Kunji @Mitocarriers and @BrodinPetter for examining! @MRC_LMS @ImperialMDR @ImperialMed #PhDone #ProudPI #ChainFlorey #ClinicianScientist

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Proud @MRC_LMS PhD supervisors @WiebkeArlt Will Scott & @BrodinPetter - #ChainFlorey MB2PhD student @meryemertugrull has passed the PLAB1 with flying colours and on her way to become a doctor with license to practice soon - many thanks also to peer mentor @eka_melson for support

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Amazing new work from @CHILDSTUDY - Microbial colonization programs are structured by breastfeeding and guide healthy development. Well done @MeghanAzad and all! cell.com/cell/fulltext/…


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Voláme sa Cyril a Metod a priniesli sme Vám 23 percentnú DPH na písmo


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Hormone study reveals why men were worse hit by Covid-19 - Radio Sweden sverigesradio.se/artikel/hormon…


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

6/6 Sex hormone mediated regulation is dynamic and allows for changes in relation to changing needs during the life course (puberty, menstruation, pregnancy). We speculate that hormones regulation balances investments into reproduction (female) vs muscle growth (males) by…

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

5/6 Importantly, not all immune system components changed during 12 months of testosterone and adaptive B/T cell subsets were relatively less affected.


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

4/6 Conversely, we find potentiation of pro-inflammatory responses (TNF etc) by monocytes upon testosterone, providing an explanation to cytokine storms seen more frequently in males w severe infections.

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

3/6 We find ⬇️ numbers, phenotypic adaptation and functional attenuation (⬇️IFN-I) of pDCs upon testosterone in vivo. This is intriguing given the role of IFN-I responses in female-biased autoimmune dx, like lupus, MS etc, but also in viral infections like SARS-CoV2 typically…

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

2/6 This longstanding collab w Nils Landegren @UU_University started 2016 and was led by the amazing @LkanthTadepally (experiments), @FabianSardh (coordination) and data analysis by @RikardForlin and former postdoc @consiglio_cr . We are deeply indebted to patients and clinical…


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

New paper out @Nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming…

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

I am so fortunate to work with amazingly talented and kind people!

Congratulations to Dr. Ziyang Tan and the Brodin Lab team. So much talent 💕 @LkanthTadepally @RikardForlin @BrodinPetter



Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

finally! I've been waiting for this one. Can't wait to read this. Life history theory and more @RMedzhitov @YaleEvoMed

Evolutionary Medicine, 2nd Ed Will be out in a couple of weeks!

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

I am abstaining from voting today. Last time I exercised my right as a citizen and asked legitimate Qs to my candidate President Paul Kagame, I was not only threatened by his office, but they also went out of their way to hurt me and sabotage my life.1/2 #RwandaDecides

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Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

Bad debate nights happen. Trust me, I know. But this election is still a choice between someone who has fought for ordinary folks his entire life and someone who only cares about himself. Between someone who tells the truth; who knows right from wrong and will give it to the…


Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Reposted

So grateful of being surrounded by such amazing people - The Villablanca-Engblom labs summer bbq was beautiful, multicultural and fun! @camillaengblom @ejvillablanca

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