Danny IncaRNAto
@incaRNAtolabAssociate Professor in Molecular Genetics @univgroningen @ResearchGbb | CSO @serna_bio | #RNA structure ensembles & dynamics | 🦋 https://t.co/VfgPl0N4ay
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Very excited to share our latest preprint, led by rockstar post-doc @i_borovska Our humble attempt to begin exploring #RNA secondary structure ensembles in a living cell (biorxiv.org/content/10.110…) (1/n)
A survey of thousands of #lncRNAs using CRISPR screening across multiple cell lines identifies 46 essential and >700 context-specific lncRNAs, crucial for cell survival! Check it out: cell.com/cell/fulltext/…
Please retweet 🙏: 2 @ERC_Research-funded Post-doc positions are available in our lab to investigate #RNA structural ensemble and their dynamics in living cells. Application link: rug.nl/about-ug/work-…
Pleased to share our new article "Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections" out in @NAR_Open academic.oup.com/nar/advance-ar…
A very nice PhD project in my lab in collaborations with @DrZoeWaller and @ant_dodd! Please share it🙏! biodtp.norwichresearchpark.ac.uk/projects/inves…
Extremely powerful and exciting: AI-driven Foundation Model - by @YiliangDing @EMBLEvents #EESRNA. I believe this would largely accelerate the development of Biology: AI-guided experimental design! A ms in press @NatureMachineIntelligence
We are very excited to introduce ATENA (Approach to Target Exact Nucleic Acid alternative structures), as a new tool to target individual G4s in living cells using chemically modified CRISPR/Cas9 proteins👇👇👇 biorxiv.org/content/10.110…
Fantastic work on the mode of action of an #RNA-targeted splicing modulator on the recognition of 5' splice sites by the U1 snRNP, check it out!
Happy to say our collaborative work, spearheaded by David White and with @RemixThera, is now out! In this work we studied 5' splice site recognition by U1 and its modulation by a drug called branaplam. nature.com/articles/s4146…
Since the discovery of RNA splicing and its role in gene expression, researchers have sought a set of rules, an algorithm or a computational model that could predict the splice isoforms, and their frequencies, produced from any transcribed gene in a specific cellular context
#RNA Framework, critical update. To all the users: during the last commit a bug was inadvertently introduced in the rf-count module. This is now fixed. We advise you to pull the latest commit asap. Apologies for any inconvenience this might have caused! github.com/dincarnato/RNA…
Many very good opportunities here to focus on cutting edge science projects in the biological sciences
Our PhD applications have launched today! We have projects in epigenetics, signalling and immunology 🥼 Check out the projects on our website: babraham.ac.uk/work-and-study…
SHAPEwarp v2.1.0 for #RNA SHAPE-guided similarity search is out (github.com/dincarnato/SHA…), featuring a massive 4 to 5-fold speed up! Also, several new databases added to SHAPEwarp-web (shapewarp.incarnatolab.com). Check it out!
New 📜 in @NatureSMB - "Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity", by Sveta in my lab, @omerz213 @ericmiska and Lau and Greg @kudlalab Been a while since preprint, so a 🧵 nature.com/articles/s4159…
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Who to follow
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MeyerLab
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Gene Yeo’s Lab at UC San Diego
@yeo_lab -
Joan Steitz Lab
@SteitzLab -
Kwok Lab
@kitkwok6 -
Woodson Lab
@woodson_lab -
BevilacquaLab
@phil_bevilacqua -
The RNA Society
@RNASociety -
OSU Center for RNA Biology
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UMich RNA Center 〽️🧬
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Javier F Caceres
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Jinwei Zhang Lab
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