Dr Helen Matthews
@helenkmatthewsCell biologist | Group Leader & Sir Henry Dale Fellow @MCB_Sheffield | Loves mitosis & cell mechanics | Cancer researcher who had #breastcancer | she/her
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Keep an eye out on the 21st of November and you might catch a glimpse of the concourse all lit up for #pancreaticcancerawarenessmonth @TUOS_Cancer @SheffieldSU
📢 Fully-funded 4-year @DiMeN_DTP PhD opportunity in our lab! 🔬 Exciting cancer cell biology collab with @hannes_maib & Liz Smythe @MCB_Sheffield to use recombinant biosensors to image active KRAS in #pancreaticcancer 👇Apply by 13th Dec findaphd.com/phds/project/m…
It was an honour to give the Insigneo Seminar in Mechanobiology @sheffielduni 🧪⚙️🧬! Many thanks to @IvanaBarbaric3, @helenkmatthews, @a_tsakiridis, @ERainero_lab, @AlexGFletcher & @Ruby_Peters_ (@TLM_Cambridge emerita 😉) for such a stimulating & enjoyable visit😀!
David Ish-Horowicz FRS (1948-2024): outstanding scientific discovery, with a unique touch of selfless humanity An Obituary by Ilan Davis (@ilandavis), with his personal reflections on David's unique approach to science and scientific friendship: journals.biologists.com/dev/article/15…
Don't miss this fantastic conference that brings together different scientific communities to celebrate the 100th anniversary of @Co_Biologists! It will include the annual @Official_BSCB @_BSDB_ meeting so an absolute must 🤩 Can't wait!
Check out our new preprint on bioRxiv. We show that NuMA localisation is sensitive to tissue stretch and acts to fine-tune division orientation. Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation biorxiv.org/content/10.110…
PI3K dependent rearrangement of the actin cytoskeleton following the addition of Class I PAK kinase-inhibitor. Please read about it in our pre-print!
Check out our new preprint where we show that cell shape noise facilitates shape transitions! It was a heroic project led by @WolframPonisch (theory) and @IskraYanakieva (experiments) and a great collaboration with @GSalbreux Summary in Wolfram’s thread biorxiv.org/content/10.110…
We are super excited to present our new @biorxiv preprint! biorxiv.org/content/10.110… The Waddington landscape is a classic metaphor in gene expression studies, but is there a similar landscape for cell shape? And can it help us to understand cell shape change? (1/8)
@MRC_LMS 4y PhD studentships for Oct 2025 start have gone live! Including *two* working with our Cell Cycle Control team. Check them all out here: lms.mrc.ac.uk/study-here/phd…
We describe the generation of a precision virotherapy that can selectively infect and deliver "suicide genes" to Pancreatic ductal adenocarcinoma via αvβ6 integrin, a tumour-selective marker.
@IvaskaLab THE review on 'everything' you have ever wanted to know about integrins in cancer, invasion and migration. Many cool new concepts highlighted from the beautiful research from experts in the field 👇@MeganChastney #VMLeppänen #JasminKaivola rdcu.be/dVB6n
Congratulations Marianne! It was a pleasure to be examiner for such an interesting thesis.
I’m very happy to share that I passed my PhD viva at King's College London last week! 🎉
Aoki, K., Kondo, Y., Naoki, H., Hiratsuka, T., Itoh, R. E., & Matsuda, M. (2017). Propagating Wave of ERK Activation Orients Collective Cell Migration. Developmental cell, 43(3), 305–317.e5. #EpithelialMechanics sciencedirect.com/science/articl…
V interesting new work on the regulation of cell migration (via rear contraction) by Cdk1-cyclin complexes throughout the cell cycle
First paper as a PI now available on bioRxiv, an excellent collaboration with @DrMCJones33, @integrintraffic, Mike Jones (@MCJoneslab ): Differential roles of cyclin-CDK1 complexes in cell migration and invasion biorxiv.org/content/10.110…
And finishing the day with a great talk from our postdoc @VicHart33 at @Official_BSCB NECB @MCB_Sheffield 👏
Great to be back at the NECB for another year. Such a great cell biology community
Today we are hosting the 20th North of England Cell Biology (NECB) forum @UniOfYork Thanks to @Official_BSCB and @BiochemSoc for the generous sponsorship! Lots of great talks lined up followed by drinks and food with our local sponsor @brewyorkbeer 🧬 🧫🧪 🍻
The Making Lab 8th Biological making workshop will be on the 22th October 2024 at The Francis Crick Institute! Want to hear more about engineering experimental tools, Making&Prototyping & strengthen your tech network? Registrations are open. Don't forget to submit an abstract !
Last two weeks to submit your abstracts for the Biological Making Workshop 2024!! The deadline is the 13th September! eventbrite.co.uk/e/biological-m…
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