John Foley
@foleyjfEditor of Science Signaling. Views here are mine, not those of AAAS. Now found elsewhere: @jffoley.bsky.social; @[email protected]
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Interested in neuroscience research? Check out a collection of recent research papers on the Science Signaling (@scisignal) homepage: science.org/journal/signal…
I just subscribed to Holden’s Newsletter holdenthorp.substack.com/?r=4x94&utm_me…
In this week's Editors’ Choice piece, we highlight the work of @_SantiagoCuesta, @VanessaSperand2, and co. in @cellhostmicrobe, which suggests that targeting the effects of cocaine on the gut microbiome may be a way to treat addiction. Read more here: scim.ag/Op
Delighted our review "The path to venetoclax resistance is paved with mutations, metabolism, and more" @ScienceTM science.org/doi/10.1126/sc… Fantastic work by @MMResearchIRE @_flanaganl & @DanielAlencar_R @PhysiologyRCSI @RCSI @RCSI_Research
🚨 EVENT ALERT 🚨 Join us virtually for the @WhiteHouse Summit on STEMM Equity and Excellence with @WHOSTP & @DorisDukeFdn on Monday, Dec. 12 at 10 a.m. ET. Diversity and equity in #STEMM are critical to American competitiveness and innovation. Watch here: fal.cn/3uhT3
In a new study, researchers connect #PulmonaryArterialHypertension and #PAVSMC proliferation to a lack of the TSC2 protein—and show that an experimental drug can restore TSC2 abundance and mitigate pulmonary hypertension in rodents. @YuanjunS @UCDavisPCCM scim.ag/Nq
An experimental drug ... improved lung function and mitigated pulmonary hypertension in rodents, suggesting similar strategies could address the lack of treatments for the disorder. In @scisignal 📰: science.org/doi/10.1126/sc… 📷Credit: Shen, et al., Science Signaling (2022)
.@WorldSciForum, the first ever on the continent of Africa, began with remarks from @AAAS President @SudipSParikh, who paraphrased former AAAS President Margaret Mead, saying we should never doubt that a small group of people committed to science and equity can change the world.
Synaptic activity–dependent changes in the hippocampal palmitoylome science.org/doi/10.1126/sc…
Happy to share our recent paper in Science Signaling : science.org/doi/10.1126/sc… And we are on the cover of the magazine!😃
Researchers show that the kinase VPS34 adjusts #endocytosis, nutrient transport, and antiviral responses in the kidneys, suggesting that the protein might be a therapeutic target to protect this organ from viral infections. @mrins01 @UKEHamburg #KidneyBiology
We really appreciate that Science Signaling highlighted our recent paper in Editors' Choice section. science.org/doi/10.1126/sc…
Each week, we take a moment to recognize the contributions of our Science Signaling Board members. Today, we thank Dr. Toby Gibson at the EMBL Heidelberg (scim.ag/JL) for his expert advice on protein domain analysis, bioinformatics, and proteomics. @embl
In this week’s Editors’ Choice piece, we highlight the work of Knizkova, Stepanek, Draber, and colleagues in @NatImmunol that shows that the tetra-transmembrane protein CMTM4 acts as a subunit of the IL-17 receptor. Read a summary in the new issue: scim.ag/JF
A new Focus in this week’s issue highlights discussions from a recent scientific meeting celebrating the career of Colin W. Taylor, a researcher at Cambridge University and a leading pioneer in #CalciumSignaling research. @uclcdb scim.ag/Jg
Scientists have answered a longstanding question about how the highly studied #TGFbeta activates the kinase Src, an enzyme linked to the development and progression of #cancer. Check out the paper in @SciSignal: scim.ag/I4
Study in @scisignal demystifies how a kinase coordinates the retention of nutrients in the kidneys & hints that targeting may protect kidney cells from infections with viruses such as SARS-CoV-2. 📰: science.org/doi/10.1126/sc… 📷: M.M. Rinschen, et al., Science Signaling (2022)
CMTM4 makes IL-17 signaling more complex science.org/doi/10.1126/sc…
This week’s new issue of Science Signaling has arrived! Research demystifies how an enzyme coordinates nutrient retention in the kidneys, a recent scientific meeting celebrates a pioneer in calcium signaling, and more. scim.ag/Hd
Quantal leaps in understanding Ca2+ signaling: A “Taylored” approach science.org/doi/10.1126/sc…
And this amazing year also brought us another nice paper 😊 that now we can share with you. Special Congrats to Bianca Cali and @BethMarcuzzi Atypical CXCL12 signaling enhances neutrophil migration by modulating nuclear deformability science.org/doi/10.1126/sc…
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