Diego Pesce
@diepesceSynthetic biologist, evolutionary biochemist, overall a natural philosopher. Sometimes musician, dancer, and teacher. Tweet also for @RNAMaker.
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If like me you've run hundreds of minipreps but never bothered to read up on why they extract plasmid but not chromosomal DNA, a recent tweet by @joel_rosenbaum finally motivated me to look it up. From Biennium and Doly 1979:
Facing New Heights!: Last week we took a team trip to neighboring canton Schwyz. We were able to take a step back from the usual day-to-day business, reset, and nourish our team relationship. Now we are back and as fresh as a daisy! 🌼 #teambuilding #transparencyisinourdna
Race to survival during antibiotic breakdown determines the minimal surviving population size biorxiv.org/content/10.110…
The fitness landscape of TEM-1 β-lactamase is stratified and inverted by sublethal concentrations of cefotaxime biorxiv.org/cgi/content/sh… #biorxiv_evobio
Machine learning-aided engineering of hydrolases for PET depolymerization | Nature nature.com/articles/s4158…
Co-evolution of interacting proteins through non-contacting and non-specific mutations nature.com/articles/s4155…
The registration is now open for iDEC2022! idec.io We invite all students from high-school to PhD to compete in the 3 directed evolution areas: -Molecular⚛️ -Pathway🔁 -Genome🧬 Teams will present their solution at the iDEC2022 festival with great talks and prices
The 1st iDEC Festival opens! @ProfTomEllis @nadanai263 @zakir_tnimov @FrostJiangShan @Corbicula1 Thanks to all the teams, judges, volunteers! @imperialiDEC @DrLeoRios @meeeeechigan @diepesce @SvenjaVinke @FankangMeng @StefanBassler @HuandiXu @MingzheChen3 @alexis_zeng
Evolutionary transition from a single RNA replicator to a multiple replicator network biorxiv.org/cgi/content/sh… #bioRxiv
Open postdoc position in our group @ETH_en Please RT. evol.mcmaster.ca/~brian/evoldir…
Towards an engineering theory of evolution | Nature Communications nature.com/articles/s4146…
Our new paper on experimental evolution of reconstructed ancestral proteins: Historical contingency is the dominant factor in evolution of protein sequence variation, even under strong selection. Out today in @eLife 1/ elifesciences.org/articles/67336
Our complete landscape of antimicrobial peptides: nature.com/articles/s4200… work of @PsamClark with @curtisbdobson @Lynda_K_Harris plus Tom Jowitt and me in @CommsBio Thanks to @uom_bbsrc_dtp not to mention @dbkell for setting up the collaboration!
I would like to invite all students to apply for the first International Directed Evolution Competition 2021! @iDEC2021 @EdinburghUni Teams will compete in the tracks of molecular, pathway or genome directed evolution with a focus on methods or output. idec.io
Interested in directed evolution? Check out the @iDEC2021 comp for students (undergrad, masters, high school) to compete in teams on projects in 1/3 tracks: enhancing molecules, optimizing pathways or designing new strains. PhD students & postdocs can sign on as advisors too!
I would like to invite all students to apply for the first International Directed Evolution Competition 2021! @iDEC2021 @EdinburghUni Teams will compete in the tracks of molecular, pathway or genome directed evolution with a focus on methods or output. idec.io
Metabolic fitness landscapes predict the evolution of antibiotic resistance | Nature Ecology & Evolution nature.com/articles/s4155…
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